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Fabrication of naturel pumice/hydroxyapatite composite for biomedical engineering

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dc.contributor.authorOKTAR, FAİK NÜZHET
dc.contributor.authorsKomur, Baran; Lohse, Tim; Can, Hatice Merve; Khalilova, Gulnar; Gecimli, Zeynep Nur; Aydogdu, Mehmet Onur; Kalkandelen, Cevriye; Stan, George E.; Sahin, Yesim Muge; Sengil, Ahmed Zeki; Suleymanoglu, Mediha; Kuruca, Serap Erdem; Oktar, Faik Nuzhet; Salman, Serdar; Ekren, Nazmi; Ficai, Anton; Gunduz, Oguzhan
dc.date.accessioned2022-03-14T08:15:15Z
dc.date.available2022-03-14T08:15:15Z
dc.date.issued2016-12
dc.description.abstractBackground: We evaluated the Bovine hydroxyapatite (BHA) structure. BHA powder was admixed with 5 and 10 wt% natural pumice (NP). Compression strength, Vickers micro hardness, Fourier transform infrared spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction studies were performed on the final NP-BHA composite products. The cells proliferation was investigated by MTT assay and SEM. Furthermore, the antimicrobial activity of NP-BHA samples was interrogated. Results: Variances in the sintering temperature (for 5 wt% NP composites) between 1000 and 1300 degrees C, reveal about 700 % increase in the microhardness (similar to 100 and 775 HV, respectively). Composites prepared at 1300 degrees C demonstrate the greatest compression strength with comparable result for 5 wt% NP content (87 MPa), which are significantly better than those for 10 wt% and those that do not include any NP (below 60 MPa, respectively). Conclusion: The results suggested the optimal parameters for the preparation of NP-BHA composites with increased mechanical properties and biocompatibility. Changes in micro-hardness and compression strength can be tailored by the tuning the NP concentration and sintering temperature. NP-BHA composites have demonstrated a remarkable potential for biomedical engineering applications such as bone graft and implant.
dc.identifier.doi10.1186/s12938-016-0203-0
dc.identifier.eissn1475-925X
dc.identifier.pubmed27388324
dc.identifier.urihttps://hdl.handle.net/11424/241308
dc.identifier.wosWOS:000379683500001
dc.language.isoeng
dc.publisherBMC
dc.relation.ispartofBIOMEDICAL ENGINEERING ONLINE
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBioceramics
dc.subjectNatural pumice
dc.subjectBovine hydroxyapatite
dc.subjectBioinspired composites
dc.subjectGLASS-REINFORCED HYDROXYAPATITE
dc.subjectTHERMAL-DECOMPOSITION
dc.subjectMECHANICAL-PROPERTIES
dc.subjectTRICALCIUM PHOSPHATE
dc.subjectBONE
dc.subjectPUMICE
dc.subjectMICROSTRUCTURE
dc.subjectDENSITY
dc.subjectAPATITE
dc.subjectMGO
dc.titleFabrication of naturel pumice/hydroxyapatite composite for biomedical engineering
dc.typearticle
dspace.entity.typePublication
local.avesis.id9ada0277-fbb4-4609-9c9b-a5900b6e3fb1
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber81
local.journal.numberofpages20
local.journal.quartileQ3
oaire.citation.titleBIOMEDICAL ENGINEERING ONLINE
oaire.citation.volume15
relation.isAuthorOfPublication5ba0a0e0-ebae-43a6-855c-0aabb90021f4
relation.isAuthorOfPublication.latestForDiscovery5ba0a0e0-ebae-43a6-855c-0aabb90021f4

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