Publication:
The effect of topical ethanol extract of Cotinus coggygria Scop. on cutaneous wound healing in rats

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dc.contributor.authorŞEN, ALİ
dc.contributor.authorsAksoy, Halil; Sancar, Mesut; Sen, Ali; Okuyan, Betul; Bitis, Leyla; Uras, Fikriye; Akakin, Dilek; Cevik, Ozge; Kultur, Sukran; Izzettin, Fikret Vehbi
dc.date.accessioned2022-03-12T20:28:47Z
dc.date.available2022-03-12T20:28:47Z
dc.date.issued2016
dc.description.abstractThe aim of this study is to determine the cutaneous wound healing effects of the ethanol extract of Cotinus coggygria leaves in rats by excision wound model to provide scientific evidence for the traditional use of C. coggygria Scop. The levels of malondialdehyde, catalase, superoxide dismutase, glutathione and hydroxyproline were investigated in wound tissues. Histopathological examination was also performed. The hydroxyproline content of the granulation tissue and the glutathione levels were both significantly higher in the treatment group than in the control group (p < 0.05 for both); while the malondialdehyde levels were significantly lower in the treatment group (p < 0.05). These results were supported with histological results. The ethanol extract of C. coggygria Scop could be considered as an effective agent in wound healing in accordance with its traditional use.
dc.identifier.doi10.1080/14786419.2015.1019349
dc.identifier.eissn1478-6427
dc.identifier.issn1478-6419
dc.identifier.pubmed25775378
dc.identifier.urihttps://hdl.handle.net/11424/233974
dc.identifier.wosWOS:000375841100014
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS LTD
dc.relation.ispartofNATURAL PRODUCT RESEARCH
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectwound healing
dc.subjecthydroxyproline
dc.subjectCotinus coggygria Scop
dc.subjectCONSTITUENTS
dc.subjectCHELATION
dc.subjectCOLLAGEN
dc.titleThe effect of topical ethanol extract of Cotinus coggygria Scop. on cutaneous wound healing in rats
dc.typearticle
dspace.entity.typePublication
local.avesis.idecbacb41-b8ad-40af-a6dc-d159b3e868a9
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages4
local.journal.quartileQ2
oaire.citation.endPage455
oaire.citation.issue4
oaire.citation.startPage452
oaire.citation.titleNATURAL PRODUCT RESEARCH
oaire.citation.volume30
relation.isAuthorOfPublication9e088078-d757-41a4-afc6-909f32031cb1
relation.isAuthorOfPublication.latestForDiscovery9e088078-d757-41a4-afc6-909f32031cb1

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