Publication:
Development of an animal model for type II sulcus (sulcus vergeture)

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dc.contributor.authorENVER, NECATİ
dc.contributor.authorsBatıoğlu-Karaaltın A., Ugurlar M., ENVER N., Erdur Z. B., YILMAZ Y. Z., Bozkurt E. R.
dc.date.accessioned2023-04-07T08:08:40Z
dc.date.available2023-04-07T08:08:40Z
dc.date.issued2023-01-01
dc.description.abstractObjectives: To develop a reproducible experimental animal model for sulcus vergeture in rabbits. Study Design: Experimental animal study. Material Method: We evaluated three methods of inducing sulcus in twelve New Zealand white rabbits to produce a sulcus model. Experimental groups comprised: group 1 (n = 4) underwent submucosal injury following endolaryngeal epithelial incision; group 2 (n = 4) received submucosal injury via thyrotomy; group 3 (n = 4) received submucosal injury via thyrotomy, followed with horizontal mucosal lateralization suture. Right vocal folds of the rabbits underwent surgery to produce sulcus vocalis and left vocal folds were used for the comparison. In the sixth week after the procedure, the rabbits were sacrificed and the larynxes were harvested and analyzed histopathologically. Results: No animals in group 1 or 2 developed sulcus vocalis. Sulcus formation was observed in all rabbits in group 3, under endoscopic examination and microscopic sulcus formation was demonstrated for the first, second, and third rabbits. An epithelial depression area was seen at the glandular ductal opening zone for the fourth rabbit, but it could also be accepted as a sulcus formation. Conclusion: We successfully developed a reproducible survival model for sulcus using a submucosal injury via thyrotomy, followed with a horizontal mucosal lateralization suture. This model provides the groundwork for future research into the applicability of new approaches for sulcus management.
dc.identifier.citationBatıoğlu-Karaaltın A., Ugurlar M., ENVER N., Erdur Z. B., YILMAZ Y. Z., Bozkurt E. R., "Development of an Animal Model for Type II Sulcus (Sulcus Vergeture)", Journal of Voice, 2023
dc.identifier.doi10.1016/j.jvoice.2023.01.001
dc.identifier.issn0892-1997
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85146549503&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/288431
dc.language.isoeng
dc.relation.ispartofJournal of Voice
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectKulak Burun Boğaz
dc.subjectHemşirelik
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectSurgery Medicine Sciences
dc.subjectOtolaryngology
dc.subjectNursing
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectHEMŞİRELİK
dc.subjectKULAK BURUN BOĞAZ
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectNURSING
dc.subjectOTORHINOLARYNGOLOGY
dc.subjectKonuşma ve İşitme
dc.subjectLPN ve LVN
dc.subjectOtorhinolaryngology
dc.subjectSpeech and Hearing
dc.subjectLPN and LVN
dc.subjectExperimental sulcus modeling—Larynx—Sulcus vocalis—Vocal fold
dc.subjectExperimental sulcus modeling
dc.subjectLarynx
dc.subjectSulcus vocalis
dc.subjectVocal fold
dc.titleDevelopment of an animal model for type II sulcus (sulcus vergeture)
dc.typearticle
dspace.entity.typePublication
local.avesis.id2ec5a190-45c6-477d-95dc-919dfb92d7fa
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication47e0392d-e1ee-45d3-8f90-9dbccd94970b
relation.isAuthorOfPublication.latestForDiscovery47e0392d-e1ee-45d3-8f90-9dbccd94970b

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