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The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LCMS/MS

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dc.contributor.authorAYAZ SEYHAN, SERAP
dc.contributor.authorsSeyhan S., Yalcin G., AYAZ SEYHAN S.
dc.date.accessioned2023-02-20T10:42:57Z
dc.date.available2023-02-20T10:42:57Z
dc.date.issued2023-01-01
dc.description.abstract© 2023 Marmara University Press.Ellagic acid (EA) and resveratrol (RES) are phenolic compounds naturally found in fruits. However, a significant amount of RES and EA is present in berries and their effective isolation enables the production of functional foods. In this study, EA and RES found in four highbush (Vaccinium corymbosum) blueberry varieties (Bluecrop, Brigitta, Darrow and Bluejay) were analyzed simultaneously for the first time. A chromatographic method was developed for EA and RES by HPLC-DAD and LC-MS/MS. Furthermore, pressurized liquid extraction (PLE) method was performed for the extraction of EA and RES from blueberry samples. LOD (limit of detection) and LOQ (limit of quantification) were determined as 0.1898x10-6 mol.L-1 and 0.5694x10-6 mol.L-1 for RES, 0.1271x10-6 mol.L-1 and 0.3814x10-6 mol.L-1 for EA, respectively. All the results were reevaluated according to 91.85% and 84.97% recovery value, for EA and RES, respectively. The amount of EA and RES were found out in the range of 1.65-9.16 mg/kg and 2.95-9.31 mg/kg in the lyophilized blueberry varieties.
dc.identifier.citationSeyhan S., Yalcin G., AYAZ SEYHAN S., "The extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LCMS/MS", Journal of Research in Pharmacy, cilt.27, sa.1, ss.311-320, 2023
dc.identifier.doi10.29228/jrp.313
dc.identifier.endpage320
dc.identifier.issn2630-6344
dc.identifier.issue1
dc.identifier.startpage311
dc.identifier.urihttps://avesis.marmara.edu.tr/api/publication/241c6154-91ce-44c7-901b-5cf5336c94bb/file
dc.identifier.urihttps://hdl.handle.net/11424/286587
dc.identifier.volume27
dc.language.isoeng
dc.relation.ispartofJournal of Research in Pharmacy
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTemel Eczacılık Bilimleri
dc.subjectEczacılık
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectBasic Pharmaceutics Sciences
dc.subjectPharmacology and Therapeutics
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectLife Sciences (LIFE)
dc.subjectPHARMACOLOGY & TOXICOLOGY
dc.subjectPHARMACOLOGY & PHARMACY
dc.subjectGenel Farmakoloji, Toksikoloji ve Eczacılık
dc.subjectFarmakoloji (tıbbi)
dc.subjectGeneral Pharmacology, Toxicology and Pharmaceutics
dc.subjectPharmacology (medical)
dc.subjectBlueberry
dc.subjectellagic acid
dc.subjectHPLC
dc.subjectLC-MS/MS
dc.subjectresveratrol
dc.titleThe extraction and determination of ellagic acid and resveratrol in blueberry species by HPLC-DAD and LCMS/MS
dc.typearticle
dspace.entity.typePublication
local.avesis.id241c6154-91ce-44c7-901b-5cf5336c94bb
local.indexed.atSCOPUS
relation.isAuthorOfPublication718255e1-6de8-47ba-8bfd-6a8c55a04479
relation.isAuthorOfPublication.latestForDiscovery718255e1-6de8-47ba-8bfd-6a8c55a04479

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