Publication: Chemical composition, antiradical, and enzyme inhibitory potential of essential oil obtained from aerial part of Centaurea pterocaula Trautv
No Thumbnail Available
Date
2021
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
TAYLOR & FRANCIS INC
Abstract
The chemical composition, free radical scavenging, alpha-amylase inhibitory, and 5-lipoxygenase inhibitory activity of the essential oil obtained from the aerial parts of Centaurea pterocaula Trautv. were examined. Twenty-nine compounds corresponding to 93.2% of the oil were identified in the oil of C. pterocaula. Hexadecanoic acid (13.9%), caryophyllene oxide (11.5%), spathulenol (11.4%), (E)-beta-damascenone (5.0%), hexahydrofarnesyl acetone (5.0%), and tetradecanoic acid (4.9%) were the main compounds of the oil. The oil exhibited good anti-inflammatory activity, inhibiting 5-lipoxygenase with an IC50 value of 86.22 mu g/mL. The oil was found to be active against DPPH radical and alpha-amylase with IC50 values of 83.05 and 79.66 mu g/mL respectively, while it showed moderate activity against ABTS radicals with IC50 value of 360.9 mu g/mL. To the best of our knowledge, this is first report on the chemical composition of C. pterocaula essential oil from Turkey; as well as on the biological activity of its essential oil.
Description
Keywords
Centaurea pterocaula, essential oil composition, antidiabetic activity, anti-inflammatory activity, antioxidant activity, GROWING WILD, MEDICINAL-PLANTS, VOLATILE CONSTITUENTS, ANTIOXIDANT, EXTRACTS, ASTERACEAE, DC., L., ANTIMYCOBACTERIAL, COMPONENTS