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Evaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes’ Competitive Performance

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dc.contributor.authorULUCAN, KORKUT
dc.contributor.authorsBulgay C., Bayraktar I., Kazan H. H., YILDIRIM D. S., ZORBA E., Akman O., ERGÜN M. A., CERİT M., ULUCAN K., EKEN Ö., et al.
dc.date.accessioned2023-03-21T08:47:00Z
dc.date.available2023-03-21T08:47:00Z
dc.date.issued2023-03-01
dc.description.abstractThe present study aimed to examine the vitamin D receptor (VDR), rs2228570 polymorphism, and its effect on elite athletes’ performance. A total of 60 elite athletes (31 sprint/power and 29 endurance) and 20 control/ physically inactive, aged 18–35, voluntarily participated in the study. The International Association of Athletics Federations (IAAF) score scale was used to determine the performance levels of the athletes’ personal best (PB). Whole exome sequencing (WES) was performed by the genomic DNA isolated from the peripheral blood of the participants. Sports type, sex, and competitive performance were chosen as the parameters to compare within and between the groups by linear regression models. The results showed no statistically significant difference between the CC, TC, and TT genotypes within and between the groups (p > 0.05). Additionally, our results underlined that there were no statistically significant differences for the association of rs2228570 polymorphism with PBs within the groups of the (p > 0.05) athletes. The genetic profile in the selected gene was similar in elite endurance, sprint athletes, and in controls, suggesting that rs2228570 polymorphism does not determine competitive performance in the analyzed athlete cohort.
dc.identifier.citationBulgay C., Bayraktar I., Kazan H. H., YILDIRIM D. S., ZORBA E., Akman O., ERGÜN M. A., CERİT M., ULUCAN K., EKEN Ö., et al., "Evaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes’ Competitive Performance", Healthcare (Switzerland), cilt.11, sa.5, 2023
dc.identifier.doi10.3390/healthcare11050681
dc.identifier.issn2227-9032
dc.identifier.issue5
dc.identifier.urihttps://avesis.marmara.edu.tr/api/publication/c74c7ba1-c7b3-4e87-9348-db3006f700d7/file
dc.identifier.urihttps://hdl.handle.net/11424/287694
dc.identifier.volume11
dc.language.isoeng
dc.relation.ispartofHealthcare (Switzerland)
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectAile Hekimliği
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectBiyoistatistik ve Tıp Bilişimi
dc.subjectMedicine
dc.subjectInternal Medicine Sciences
dc.subjectFamily Medicine
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectBiostatistics and Medical Informatics
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIBBİ BİLİŞİM
dc.subjectSAĞLIK BAKIM BİLİMLERİ VE HİZMETLERİ
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectMEDICAL INFORMATICS
dc.subjectHEALTH CARE SCIENCES & SERVICES
dc.subjectLiderlik ve Yönetim
dc.subjectSağlık Politikaları
dc.subjectTıbbi Bilişim
dc.subjectSağlık Bilgi Yönetimi
dc.subjectLeadership and Management
dc.subjectHealth Policy
dc.subjectHealth Informatics
dc.subjectHealth Information Management
dc.subjectathletics
dc.subjectendurance athletes
dc.subjectrs2228570 polymorphism
dc.subjectsprint/power athletes
dc.subjectVDR
dc.titleEvaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes’ Competitive Performance
dc.typearticle
dspace.entity.typePublication
local.avesis.idc74c7ba1-c7b3-4e87-9348-db3006f700d7
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication46774657-48cb-4f47-a639-64e428a49411
relation.isAuthorOfPublication.latestForDiscovery46774657-48cb-4f47-a639-64e428a49411

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