Publication:
Does decision tree analysis predict oral ulcer activity-related factors in patients with Behçet's syndrome?

dc.contributor.authorÇANDERELİ, ZEHRA ÖZGE
dc.contributor.authorŞİŞMAN KİTAPÇI, NUR
dc.contributor.authorAKSOY, AYSUN
dc.contributor.authorŞAHİN, ALİ
dc.contributor.authorALİBAZ ÖNER, FATMA
dc.contributor.authorİNANÇ, GÜZİDE NEVSUN
dc.contributor.authorDİRESKENELİ, RAFİ HANER
dc.contributor.authorMUMCU, GONCA
dc.contributor.authorsÇANDERELİ Z. Ö., Arslan T., Özdamar Ö., Yay M., Karaçayli Ü., ŞİŞMAN KİTAPÇI N., Adesanya A., AKSOY A., Belem J. M. F. M., Taş M. N., et al.
dc.date.accessioned2023-11-13T06:41:25Z
dc.date.available2023-11-13T06:41:25Z
dc.date.issued2023-10-01
dc.description.abstractOBJECTIVES: The study aimed to identify the interactions among treatment protocols and oral ulcer activity related factors in patients with Behçet\"s syndrome (BS) using the Classification and Regression Tree (CART) algorithm. METHODS: In this cross-sectional study, 979 patients with BS were included from16 centres in Turkey, Jordan, Brazil and the United Kingdom. In the CART algorithm, activities of oral ulcer (active vs. inactive), genital ulcer (active vs. inactive), cutaneous involvement (active vs. inactive), musculoskeletal involvement (active vs. inactive), gender (male vs. female), disease severity (mucocutaneous and musculoskeletal involvement vs. major organ involvement), smoking habits (current smoker vs. non-smoker), tooth brushing habits (irregular vs. regular), were input variables. The treatment protocols regarding immunosuppressive (IS) or non-IS medications were the target variable used to split from parent nodes to purer child nodes in the study. RESULTS: In mucocutaneous and musculoskeletal involvement (n=538), the ratio of IS use was higher in patients with irregular toothbrushing (ITB) habits (27.1%) than in patients with regular toothbrushing (RTB) habits (14.2%) in oral ulcer activity. In major organ involvement (n=441), male patients with ITB habits were more likely treated with IS medications compared to those with RTB habits (91.6% vs. 77.6%, respectively). CONCLUSIONS: Male BS patients on IS who have major organ involvement and oral ulcer activity with mucocutaneous and musculoskeletal involvement have irregular toothbrushing habits. Improved oral hygiene practices should be considered to be an integral part for implementing patient empowerment strategies for BS.
dc.identifier.citationÇANDERELİ Z. Ö., Arslan T., Özdamar Ö., Yay M., Karaçayli Ü., ŞİŞMAN KİTAPÇI N., Adesanya A., AKSOY A., Belem J. M. F. M., Taş M. N., et al., "Does decision tree analysis predict oral ulcer activity-related factors in patients with Behçet's syndrome?", Clinical and experimental rheumatology, cilt.41, sa.10, ss.2078-2086, 2023
dc.identifier.doi10.55563/clinexprheumatol/5kr2b1
dc.identifier.endpage2086
dc.identifier.issn0392-856X
dc.identifier.issue10
dc.identifier.startpage2078
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85175405511&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/294774
dc.identifier.volume41
dc.language.isoeng
dc.relation.ispartofClinical and experimental rheumatology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectİmmünoloji ve Romatoloji
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectMedicine
dc.subjectInternal Medicine Sciences
dc.subjectInternal Diseases
dc.subjectImmunology and Rheumatology
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectKlinik Tıp
dc.subjectİmmünoloji
dc.subjectALERJİ
dc.subjectROMATOLOJİ
dc.subjectClinical Medicine (MED)
dc.subjectLife Sciences (LIFE)
dc.subjectCLINICAL MEDICINE
dc.subjectIMMUNOLOGY
dc.subjectALLERGY
dc.subjectRHEUMATOLOGY
dc.subjectRomatoloji
dc.subjectİmmünoloji ve Alerji
dc.subjectRheumatology
dc.subjectImmunology and Allergy
dc.subjectImmunology
dc.titleDoes decision tree analysis predict oral ulcer activity-related factors in patients with Behçet's syndrome?
dc.typearticle
dspace.entity.typePublication
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local.indexed.atPUBMED
local.indexed.atSCOPUS
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