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Characterization and application of silver nanoparticles decorated electrospun nanofiber loaded with naringenin

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dc.contributor.authorAYAZ SEYHAN, SERAP
dc.contributor.authorBİLĞİÇ ALKAYA, DİLEK
dc.contributor.authorCESUR, SÜMEYYE
dc.contributor.authorGÜNDÜZ, OĞUZHAN
dc.contributor.authorsBirinci A., Ayaz Seyhan S., Bilğiç Alkaya D., Cesur S., Gündüz O.
dc.date.accessioned2023-03-06T12:07:51Z
dc.date.available2023-03-06T12:07:51Z
dc.date.issued2022-06-24
dc.description.abstractNanoparticles are an innovative class of functional materials. Silver nanoparticles (AgNPs) are extensively applied in different fields of science, such as biomedical science, including antibacterial, antiviral, anti-inflammatory, and anticancer therapies. Also, AgNPs are being used to produce various biomedical products to prevent infection. The application of AgNPs has been widened due to recent advances in nanotechnology. AgNPs have several important implications including medical diagnostics, therapeutics, antioxidant, antibacterial, and cytotoxic properties. Many natural biomolecules in plants (inactivated plant tissue, plant extracts and living plant) such as proteins/enzymes, amino acids, polysaccharides, alkaloids, alcoholic compounds, and vitamins could be involved in bioreduction, formation and stabilization of AgNPs. Naringenin (4′,5,7-trihydroxyflavanone) (NRG) is a bioflavonoid widely present in fruits; it has been reported to have antioxidant, free radical scavenging, anticancer, anti-inflammatory, immunomodulating and memory enhancing properties. Its antioxidant effects may make NRG a potential drug for treating Alzheimer disease (AD). Recently, NRG was found to exhibit neuroprotective effect in models of Parkinson's disease (PD) and AD, such as the ICV-STZ-induced mode of AD and the 6-OHDA model of PD. Nanocomposite materials consisting of metallic nanoparticles incorporated in or with polymers have attracted much attention because of their distinct optical, electrical and catalytic properties, which have potential applications in the fields of catalysis, bioengineering, photonics, and electronics. Silver nanoparticles have been immobilized into polymer-based nanofibers to introduce hybrid multifunctional substrates for a variety of applications. In this study, nanostructured metal-polymer hybrid (AgNPsNRG-PLA) nanofibers were obtained by electrospinning technique.The nanostructured metal-polymer hybrid (AgNPs-NRG-PLA) nanofibers were characterized by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), thermal analysis (DSC) and tensile strength and physical analyzes such as density, surface tension, particle viscosity were performed.
dc.identifier.citationBirinci A., Ayaz Seyhan S., Bilğiç Alkaya D., Cesur S., Gündüz O., \"Characterization and Application of Silver Nanoparticles Decorated Electrospun Nanofiber Loaded with Naringenin\", Applications of Chemistry in Nanosciences and Biomaterials Engineering, NanoBioMat 2022,Summer Edition, Bucuresti, Romanya, 22 - 24 Haziran 2022, ss.1
dc.identifier.startpage56
dc.identifier.urihttps://nanobiomat.eu/previous-editions/
dc.identifier.urihttps://hdl.handle.net/11424/287205
dc.language.isoeng
dc.relation.ispartofApplications of Chemistry in Nanosciences and Biomaterials Engineering, NanoBioMat 2022,Summer Edition
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectSağlık Bilimleri
dc.subjectMühendislik ve Teknoloji
dc.subjectHealth Sciences
dc.subjectEngineering and Technology
dc.subjectKlinik Tıp (MED)
dc.subjectMühendislik, Bilişim ve Teknoloji (ENG)
dc.subjectClinical Medicine (MED)
dc.subjectEngineering, Computing & Technology (ENG)
dc.titleCharacterization and application of silver nanoparticles decorated electrospun nanofiber loaded with naringenin
dc.typeconferenceObject
dspace.entity.typePublication
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