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Starch/PCL composite nanofibers by co-axial electrospinning technique for biomedical applications

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dc.contributor.authorOKTAR, FAİK NÜZHET
dc.contributor.authorsKomur, B.; Bayrak, F.; Ekren, N.; Eroglu, M. S.; Oktar, F. N.; Sinirlioglu, Z. A.; Yucel, S.; Guler, O.; Gunduz, O.
dc.date.accessioned2022-03-14T08:29:53Z
dc.date.available2022-03-14T08:29:53Z
dc.date.issued2017-12
dc.description.abstractBackground: In this study, starch and polycaprolactone (PCL), composite nanofibers were fabricated by co- axial needle electrospinning technique. Processing parameters such as polymer concentration, flow rate and voltage had a marked influence on the composite fiber diameter. Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), mechanical and physical properties (such as density, viscosity and electrical conductivity) of the composite fibres were evaluated. Moreover, a cell culture test was performed in order to determine their cytotoxicity for wound dressing application. Results: The effect of starch ratio in the solution on the properties and morphological structure of the fibers produced was presented. With lower starch concentration values, the fibers have greater ultimate tensile strength characteristic (mostly 4 and 5 wt%). According to SEM results, it can be figured out that the nanofibers fabricated have good spinnability and morphology. The mean diameter of the fibers is about 150 nm. According to results of cell culture study, the finding can be determined that the increase of starch in the fiber also increases the cell viability. Conclusions: Composite nanofibers of starch/ PCL have been prepared using a coaxial needle electrospinning technique. PCL was successfully encapsulated within starch. Fiber formation was observed for different ratio of starch. With several test, analysis and measurement performed, some important parameters such as quality and effectuality of each fiber obtained for wound dressing applications were discussed in detail.
dc.identifier.doi10.1186/s12938-017-0334-y
dc.identifier.issn1475-925X
dc.identifier.pubmed28356126
dc.identifier.urihttps://hdl.handle.net/11424/241877
dc.identifier.wosWOS:000397663100001
dc.language.isoeng
dc.publisherBMC
dc.relation.ispartofBIOMEDICAL ENGINEERING ONLINE
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNanofiber
dc.subjectElectrospinning
dc.subjectStarch
dc.subjectPCL
dc.subjectWound dressing
dc.subjectSILVER NANOPARTICLES
dc.subjectEPSILON-CAPROLACTONE
dc.subjectFABRICATION
dc.subjectNANOCOMPOSITE
dc.subjectDEGRADATION
dc.subjectBEHAVIOR
dc.subjectFIBERS
dc.subjectBLENDS
dc.titleStarch/PCL composite nanofibers by co-axial electrospinning technique for biomedical applications
dc.typearticle
dspace.entity.typePublication
local.avesis.idd06bfd46-4ef7-4eff-adb9-898aee5f5b72
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber40
local.journal.numberofpages13
local.journal.quartileQ3
oaire.citation.titleBIOMEDICAL ENGINEERING ONLINE
oaire.citation.volume16
relation.isAuthorOfPublication5ba0a0e0-ebae-43a6-855c-0aabb90021f4
relation.isAuthorOfPublication.latestForDiscovery5ba0a0e0-ebae-43a6-855c-0aabb90021f4

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