Publication:
3D-printed polylactic acid (PLA)/polymethyl silsesquioxane (PMSQ)-based scaffolds coated with vitamin E microparticles for the application of wound healing

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dc.contributor.authorULAĞ, SONGÜL
dc.contributor.authorGÜNDÜZ, OĞUZHAN
dc.contributor.authorsAnjrini N., Karabulut H., Ulağ S., Ege H., Noberi C., Dogan E., Sahin A., Gündüz O.
dc.date.accessioned2024-05-22T14:33:42Z
dc.date.available2024-05-22T14:33:42Z
dc.date.issued2024-05-01
dc.description.abstractSkin is part of the integumentary and excretory system, which helps protect the body against infections. The skin should be properly treated when it gets injured, which requires a long healing process. In this study, 15% (w/v) polylactic acid (PLA) and 1 and 2% (w/v) polymethylsilsesquioxane (PMSQ) scafolds were fabricated using 3D printing technology, and the surfaces of each scafold were coated with 5% ethylcellulose (EC)/vitamin E microparticles using the electrospray method. The morphologies of the scafolds were characterized using a scanning electron microscope (SEM), and results showed that the pore sizes of the scafolds ranged from 136 to 265μm. The vitamin E was completely released from the scafolds within 5h. MTT test was performed with fbroblast cells and results proved the biocompatibility of the scafolds. These fndings showed that the scafolds may have good potential as a wound dressing material. The biodegradation test was performed in invitro conditions and results showed that the surface coating with 5% EC/vitamin E microparticles on the 15% PLA/2% PMSQ scafolds increased the degradation rate of the scafolds.
dc.identifier.citationAnjrini N., Karabulut H., Ulağ S., Ege H., Noberi C., Dogan E., Sahin A., Gündüz O., "3D-printed polylactic acid (PLA)/polymethyl silsesquioxane (PMSQ)-based scaffolds coated with vitamin E microparticles for the application of wound healing", Emergent Materials, cilt.1, ss.1-10, 2024
dc.identifier.endpage10
dc.identifier.issn2522-5731
dc.identifier.startpage1
dc.identifier.urihttps://link.springer.com/article/10.1007/s42247-024-00711-3#citeas
dc.identifier.urihttps://hdl.handle.net/11424/296894
dc.identifier.volume1
dc.language.isoeng
dc.relation.ispartofEmergent Materials
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMühendislik ve Teknoloji
dc.subjectEngineering and Technology
dc.subjectMühendislik, Bilişim ve Teknoloji (ENG)
dc.subjectEngineering, Computing & Technology (ENG)
dc.subjectElectrospray
dc.subjectMicroparticles
dc.subjectPLA
dc.subjectPMSQ
dc.subjectVitamin E
dc.subjectWound healing
dc.subject3D printing
dc.title3D-printed polylactic acid (PLA)/polymethyl silsesquioxane (PMSQ)-based scaffolds coated with vitamin E microparticles for the application of wound healing
dc.typearticle
dspace.entity.typePublication
local.avesis.id150f9fa4-8cc0-47ff-b445-e7b507a31511
relation.isAuthorOfPublication2c8f2a30-89dc-4a84-be40-116882ea2e16
relation.isAuthorOfPublication68c12e35-8bb7-4843-ab60-8b8339546e5f
relation.isAuthorOfPublication.latestForDiscovery2c8f2a30-89dc-4a84-be40-116882ea2e16

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