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Characterization of the Biological Activity and Phenolics in Achillea lycaonica

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dc.contributor.authorRAYAMAN, ERKAN
dc.contributor.authorsTaskin, Turgut; Taskin, Duygu; Rayaman, Erkan; Dikpinar, Tugce; Suzgec-Selcuk, Sevda; Arabaci, Turan
dc.date.accessioned2022-03-12T22:26:21Z
dc.date.available2022-03-12T22:26:21Z
dc.date.issued2018
dc.description.abstractThe purpose of this study was to comparatively evaluate for the first time the antioxidant, antimicrobial, and antiurease effects of A. lycaonica extracts obtained using three extraction methods and five solvents followed by identification of the phenolic compounds obtained by Soxhlet extraction with ethyl acetate and maceration with chloroform that showed the highest total phenolic and flavonoid contents with antioxidant and antiurease activity. The phenolic compounds were identified to be chlorogenic acid, caffeic acid, rutin, dicaffeoylquinic acid, salicylic acid, luteolin, quercetin, naringenin, apigenin, and 8-hydroxy- salvigenin. Among the solvent extraction procedures, Soxhlet approach was found to have higher recoveries than other approaches. The results of 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assays showed that the 1: 1 ethanol-water Soxhlet, ethanol ultrasonic bath, and ethyl acetate Soxhlet extraction methods had the highest DPPH antioxidant activities. The ethyl acetate Soxhlet extraction method showed the highest 2, 2'-azino-bis(3-ethylbenzthiazoline- 6-sulfonic acid) diammonium salt (ABTS) and ferric reducing antioxidant power (FRAP) antioxidant activity. In addition, the chloroform maceration extraction method exhibited the highest antiurease activity. Therefore, 1: 1 Soxhlet ethanol-water, ultrasonic bath ethanol, and Soxhlet ethyl acetate extracts may be used in medicine and food production as natural antioxidant sources. In addition, maceration with chloroform may provide a potential antiurease agent.
dc.identifier.doi10.1080/00032719.2017.1318140
dc.identifier.eissn1532-236X
dc.identifier.issn0003-2719
dc.identifier.urihttps://hdl.handle.net/11424/235052
dc.identifier.wosWOS:000416519900004
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS INC
dc.relation.ispartofANALYTICAL LETTERS
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectA. lycaonica
dc.subjectantimicrobial
dc.subjectantioxidant
dc.subjectantiurease
dc.subjectliquid chromatography with quadrupole time-of-flight mass spectrometry (Q-TOF LC/MS)
dc.subjectANTIMICROBIAL ACTIVITIES
dc.subjectMETHANOL EXTRACT
dc.subjectESSENTIAL OIL
dc.subjectANTIOXIDANT
dc.subjectBIEBERSTEINII
dc.subjectUREASE
dc.titleCharacterization of the Biological Activity and Phenolics in Achillea lycaonica
dc.typearticle
dspace.entity.typePublication
local.avesis.id6e5a577b-cb30-495e-b8d1-c93e3e389500
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.numberofpages16
local.journal.quartileQ4
oaire.citation.endPage48
oaire.citation.issue1-2
oaire.citation.startPage33
oaire.citation.titleANALYTICAL LETTERS
oaire.citation.volume51
relation.isAuthorOfPublication0f89f9f8-5aa4-40cc-a61f-030fd5328d19
relation.isAuthorOfPublication.latestForDiscovery0f89f9f8-5aa4-40cc-a61f-030fd5328d19

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