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Additive manufacturing of microneedles for sensing and drug delivery

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dc.contributor.authorGÜNDÜZ, OĞUZHAN
dc.contributor.authorsBedir T., Kadian S., Shukla S., GÜNDÜZ O., Narayan R.
dc.date.accessioned2024-08-05T11:25:39Z
dc.date.available2024-08-05T11:25:39Z
dc.date.issued2024-01-01
dc.description.abstractIntroduction: Microneedles (MNs) are miniaturized, painless, and minimally invasive platforms that have attracted significant attention over recent decades across multiple fields, such as drug delivery, disease monitoring, disease diagnosis, and cosmetics. Several manufacturing methods have been employed to create MNs; however, these approaches come with drawbacks related to complicated, costly, and time-consuming fabrication processes. In this context, employing additive manufacturing (AM) technology for MN fabrication allows for the quick production of intricate MN prototypes with exceptional precision, providing the flexibility to customize MNs according to the desired shape and dimensions. Furthermore, AM demonstrates significant promise in the fabrication of sophisticated transdermal drug delivery systems and medical devices through the integration of MNs with various technologies. Areas covered: This review offers an extensive overview of various AM technologies with great potential for the fabrication of MNs. Different types of MNs and the materials utilized in their fabrication are also discussed. Recent applications of 3D-printed MNs in the fields of transdermal drug delivery and biosensing are highlighted. Expert opinion: This review also mentions the critical obstacles, including drug loading, biocompatibility, and regulatory requirements, which must be resolved to enable the mass-scale adoption of AM methods for MN production, and future trends.
dc.identifier.citationBedir T., Kadian S., Shukla S., GÜNDÜZ O., Narayan R., "Additive manufacturing of microneedles for sensing and drug delivery", Expert Opinion on Drug Delivery, 2024
dc.identifier.doi10.1080/17425247.2024.2384696
dc.identifier.issn1742-5247
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85199789706&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/297388
dc.language.isoeng
dc.relation.ispartofExpert Opinion on Drug Delivery
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTROPİKAL TIP
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectTROPICAL MEDICINE
dc.subjectFarmasötik bilim
dc.subjectYaşam Bilimleri
dc.subjectPharmaceutical Science
dc.subjectLife Sciences
dc.subject3D printing
dc.subjectadditive manufacturing
dc.subjectbiosensing
dc.subjectmicroneedles
dc.subjecttransdermal drug delivery
dc.titleAdditive manufacturing of microneedles for sensing and drug delivery
dc.typearticle
dspace.entity.typePublication
local.avesis.id3397cb84-cb20-478b-a3bc-22c9c8e18260
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication88c4b483-9bfd-4c78-8f3b-bab559753b35
relation.isAuthorOfPublication.latestForDiscovery88c4b483-9bfd-4c78-8f3b-bab559753b35

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