Publication:
Admission Glucose Level Predicts In-hospital Mortality in Patients with Acute Pulmonary Embolism Who Were Treated with Thrombolytic Therapy

Simple item page
dc.contributor.authorÇİNÇİN, AHMET ALTUĞ
dc.contributor.authorsBozbay, Mehmet; Uyarel, Huseyin; Avsar, Sahin; Oz, Ahmet; Keskin, Muhammed; Murat, Ahmet; Kaya, Adnan; Atas, Halil; Cincin, Ahmet Altug; Ugur, Murat; Eren, Mehmet
dc.date.accessioned2022-03-12T20:28:50Z
dc.date.available2022-03-12T20:28:50Z
dc.date.issued2016
dc.description.abstractElevated admission serum glucose level is associated with unfavourable clinical outcomes in various clinical conditions. The aim of this study was to investigate the relationship between admission glucose levels and in-hospital and long-term adverse clinical outcomes in patients with pulmonary embolism (PE) treated with thrombolytic therapy. A total of 183 consecutive confirmed acute PE patients (98 female and 85 male; mean age 61.9 +/- A 15.7 years) who were treated with thrombolytic therapy enrolled in this study. The study population was categorised into four quartiles according to admission serum glucose levels (group I: glucose a parts per thousand currency sign115 mg/dl; group II: glucose > 115-141 mg/dl; group III: glucose > 141-195 mg/dl; and group IV: glucose a parts per thousand yen196 mg/dl). In-hospital mortality was significantly higher in group IV (28.8 %) compared to group III (15.2 %), group II (6.6 %), and group I (2.1 %) (p < 0.001). In multivariate analysis, admission glucose level (OR 1.013, 95 % CI 1.004-1.021, p = 0.004) and admission anaemia (OR 0.602, 95 % CI 0.380-0.955, p = 0.03) were independent predictors of in-hospital mortality. The mean follow-up period was 34 months. During long-term follow-up, all-cause mortality, recurrent PE, major and minor bleeding were similar among the four groups. Admission glucose level is a simple, inexpensive, easily available, and effective laboratory parameter for predicting in-hospital mortality in patients with PE.
dc.identifier.doi10.1007/s00408-016-9858-3
dc.identifier.eissn1432-1750
dc.identifier.issn0341-2040
dc.identifier.pubmed26896039
dc.identifier.urihttps://hdl.handle.net/11424/233982
dc.identifier.wosWOS:000372909100004
dc.language.isoeng
dc.publisherSPRINGER
dc.relation.ispartofLUNG
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPulmonary embolism
dc.subjectGlucose
dc.subjectThrombolytic therapy
dc.subjectMortality
dc.subjectClinical outcomes
dc.subjectHYPERGLYCEMIA PREDICTS
dc.subjectDIABETES-MELLITUS
dc.subjectEUROPEAN-SOCIETY
dc.subjectSTROKE PATIENTS
dc.subjectHEART-FAILURE
dc.subjectTASK-FORCE
dc.subjectDIAGNOSIS
dc.subjectGUIDELINES
dc.subjectMETAANALYSIS
dc.subjectMANAGEMENT
dc.titleAdmission Glucose Level Predicts In-hospital Mortality in Patients with Acute Pulmonary Embolism Who Were Treated with Thrombolytic Therapy
dc.typearticle
dspace.entity.typePublication
local.avesis.iddeb1d720-3435-4efa-af18-96f6cd2cf242
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages8
local.journal.quartileQ3
oaire.citation.endPage226
oaire.citation.issue2
oaire.citation.startPage219
oaire.citation.titleLUNG
oaire.citation.volume194
relation.isAuthorOfPublication54255a29-54c0-43de-8bc5-39d805d1296a
relation.isAuthorOfPublication.latestForDiscovery54255a29-54c0-43de-8bc5-39d805d1296a

Files

Collections

Research Outputs