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Radiological and clinical features of multinodular and vacuolating neuronal tumor (MVNT)

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dc.contributor.authorBIYIKLI, ERHAN
dc.contributor.authorsBıyıklı E., Kursun M., Altuntas D., Bayri Y., Baltacioglu F.
dc.date.accessioned2023-01-06T08:33:59Z
dc.date.available2023-01-06T08:33:59Z
dc.date.issued2023-01-01
dc.description.abstractBackground: To investigate the imaging fndings and clinical features of multinodular and vacuolating neuronal tumor (MVNT). Methods: We retrospectively sought for cases that have suspicious imaging fndings for MVNT through the hospital information system. The patients’ demographics and clinical symptoms were extracted. All available images were re-examined. Results: Headache was the most common complaint (n=7). Other complaints included seizure, stroke-like symptoms and numbness. Conventional MRI revealed that all lesions consisted of tiny, sharply marginated, round or ovoid nodules following the gyral contour. These nodules were hyperintense on T2 and FLAIR WI, hypointense on T1 WI. All lesions were characterized by a lack of enhancement and difusion restriction. Mass efect and peripheral edema were not observed. MVNT presented as an incidental fnding in one case who complained gynecomastia and had pituitary adenoma on pituitary MRI. All lesions were supratentorial—mostly on the right side (10/11)—and located in subcortical white matter. Follow-up MRI was available for 11 patients with a mean of 14.8 months (3–40 months). No change in lesion size and morphology was observed in these follow-up images. Conclusions: Radiological and clinical follow-up data suggest MVNT may exhibit indolent behavior. If asymptomatic, patients can be followed by imaging alone. Surgery should be considered for symptomatic patients.
dc.identifier.citationBıyıklı E., Kursun M., Altuntas D., Bayri Y., Baltacioglu F., "Radiological and clinical features of multinodular and vacuolating neuronal tumor (MVNT)", EGYPTIAN JOURNAL OF NEUROSURGERY, cilt.38, sa.1, ss.1-6, 2023
dc.identifier.doi10.1186/s41984-022-00181-x
dc.identifier.endpage6
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.urihttps://avesis.marmara.edu.tr/api/publication/206ca383-f444-4b42-b187-fa01dac86a7f/file
dc.identifier.urihttps://hdl.handle.net/11424/284880
dc.identifier.volume38
dc.language.isoeng
dc.relation.ispartofEGYPTIAN JOURNAL OF NEUROSURGERY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectMultinodular and vacuolating neuronal tumor
dc.subjectMVNT
dc.subjectBrain tumor
dc.subjectMRI
dc.titleRadiological and clinical features of multinodular and vacuolating neuronal tumor (MVNT)
dc.typearticle
dspace.entity.typePublication
local.avesis.id206ca383-f444-4b42-b187-fa01dac86a7f
relation.isAuthorOfPublication1165de9e-8f7d-4493-ba54-3e8b2fffe62c
relation.isAuthorOfPublication.latestForDiscovery1165de9e-8f7d-4493-ba54-3e8b2fffe62c

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