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Non-alcoholic fatty liver disease: pathogenesis and assessing the impact of dietary bioactive compounds on the liver

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dc.contributor.authorOĞUZ, ESMA
dc.contributor.authorsOĞUZ E., Karakoyun B.
dc.date.accessioned2024-07-03T11:45:05Z
dc.date.available2024-07-03T11:45:05Z
dc.date.issued2024-05-31
dc.description.abstractNon-alcoholic fatty liver disease (NAFLD) is a pathological condition ranging from simple steatosis to non-alcoholic steatohepatitis, cirrhosis, and liver cancer. NAFLD is a complex disease mediated by metabolic, environmental, and genetic mechanisms. Many factors such as insulin resistance, lipotoxicity, inflammation, mitochondrial dysfunction, endoplasmic reticulum stress, circadian rhythm, genetics, epigenetics, dietary factors, and gut microbiota play a crucial role in the pathogenesis of NAFLD. Lifestyle changes such as healthy diet, physical activity, avoiding alcohol and smoking are involved in the NAFLD treatment. Dietary bioactive compounds including curcumin, resveratrol, catechins, quercetin, sulforaphane, epigallocatechin-3-gallate, alkaloids, vitamins, and peptides have many health promoting effects such as antioxidant, anti-inflammatory, antihypertensive, chemopreventive, and hepatoprotective. In this review, the pathophysiology of NAFLD and the effects of dietary bioactive compounds on this disease will be discussed in detail with updated information.
dc.identifier.citationOĞUZ E., Karakoyun B., "Non-alcoholic fatty liver disease: pathogenesis and assessing the impact of dietary bioactive compounds on the liver", Marmara Medical Journal, cilt.37, sa.2, ss.115-120, 2024
dc.identifier.doi10.5472/marumj.1479280
dc.identifier.endpage120
dc.identifier.issn1019-1941
dc.identifier.issue2
dc.identifier.startpage115
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196170134&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/297153
dc.identifier.volume37
dc.language.isoeng
dc.relation.ispartofMarmara Medical Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIP, GENEL & DAHİLİ
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectMEDICINE, GENERAL & INTERNAL
dc.subjectGenel Tıp
dc.subjectGeneral Medicine
dc.subjectDietary Bioactive Compounds
dc.subjectNon-Alcoholic Fatty Liver Disease
dc.subjectPathogenesis
dc.subjectDietary Bioactive Compounds
dc.titleNon-alcoholic fatty liver disease: pathogenesis and assessing the impact of dietary bioactive compounds on the liver
dc.typearticle
dspace.entity.typePublication
local.avesis.idf77f2820-7105-4564-ba0a-7bc67b9a0dea
local.indexed.atSCOPUS
relation.isAuthorOfPublication890a417b-25c6-4e99-9c9a-48f54473a855
relation.isAuthorOfPublication.latestForDiscovery890a417b-25c6-4e99-9c9a-48f54473a855

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