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Preventing infections in immunocompromised patients with kidney diseases: vaccines and antimicrobial prophylaxis

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dc.contributor.authorBERKE MENTEŞE, İLAY
dc.contributor.authorsWindpessl M., Kostopoulou M., Conway R., BERKE İ., Bruchfeld A., Soler M. J., Sester M., Kronbichler A.
dc.date.accessioned2023-12-11T08:27:12Z
dc.date.available2023-12-11T08:27:12Z
dc.date.issued2023-11-01
dc.description.abstractThe coronavirus disease 2019 (COVID-19) pandemic revealed that our understanding of infectious complications and strategies to mitigate severe infections in patients with glomerular diseases is limited. Beyond COVID-19, there are several infections that specifically impact care of patients receiving immunosuppressive measures. This review will provide an overview of six different infectious complications frequently encountered in patients with glomerular diseases, and will focus on recent achievements in terms of vaccine developments and understanding of the use of specific antimicrobial prophylaxis. These include influenza virus, Streptococcus pneumoniae, reactivation of a chronic or past infection with hepatitis B virus in cases receiving B-cell depletion, reactivation of cytomegalovirus, and cases of Pneumocystis jirovecii pneumonia in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis. Varicella zoster virus infections are particularly frequent in patients with systemic lupus erythematosus and an inactivated vaccine is available to use as an alternative to the attenuated vaccine in patients receiving immunosuppressants. As with COVID-19 vaccines, vaccine responses are generally impaired in older patients, and after recent administration of B-cell depleting agents, and high doses of mycophenolate mofetil and other immunosuppressants. Strategies to curb infectious complications are manifold and will be outlined in this review.
dc.identifier.citationWindpessl M., Kostopoulou M., Conway R., BERKE İ., Bruchfeld A., Soler M. J., Sester M., Kronbichler A., "Preventing infections in immunocompromised patients with kidney diseases: vaccines and antimicrobial prophylaxis", Nephrology Dialysis Transplantation, cilt.38, 2023
dc.identifier.doi10.1093/ndt/gfad080
dc.identifier.issn0931-0509
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85176509036&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/295516
dc.identifier.volume38
dc.language.isoeng
dc.relation.ispartofNephrology Dialysis Transplantation
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectNefroloji
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectInternal Medicine Sciences
dc.subjectInternal Diseases
dc.subjectNephrology
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectÜROLOJİ VE NEFROLOJİ
dc.subjectTRANSPLANTASYON
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectUROLOGY & NEPHROLOGY
dc.subjectTRANSPLANTATION
dc.subjectTransplantasyon
dc.subjectTransplantation
dc.subjectglomerulonephritis
dc.subjectimmunosuppression
dc.subjectinfections
dc.subjectprophylaxis
dc.subjectvaccines
dc.titlePreventing infections in immunocompromised patients with kidney diseases: vaccines and antimicrobial prophylaxis
dc.typearticle
dspace.entity.typePublication
local.avesis.id7e13a30f-988f-482b-9fd8-0b1aa91ff770
local.indexed.atPUBMED
local.indexed.atSCOPUS
local.indexed.atWOS
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relation.isAuthorOfPublication.latestForDiscovery0b6f6bf8-ef85-458f-96a2-4dc1d629ba2b

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