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Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride

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dc.contributor.authorOKTAR, FAİK NÜZHET
dc.contributor.authorsUnal, Semra; Ekren, Nazmi; Sengil, Ahmet Z.; Oktar, Faik N.; Irmak, Ster; Oral, Ozlem; Sahin, Yesim M.; Kilic, Osman; Agathopoulos, Simeon; Gunduz, Oguzhan
dc.date.accessioned2022-03-12T22:27:40Z
dc.date.available2022-03-12T22:27:40Z
dc.date.issued2018
dc.description.abstractHydroxyapatite (HA), obtained from bovine bones, was successfully reinforced with hexagonal boron nitrite (h-BN). h-BN/HA composites, with BN content up to 1.5 wt %, were sintered at various temperatures between 1000 and 1300 degrees C, in air. Well-sintered samples were obtained after sintering at 1200 and 1300 degrees C. The presence of h-BN contributed to dense, fine, and well-crystallized microstructure. The results of X-ray diffraction analysis and FT-IR spectroscopy showed that the produced composites comprised biphasic beta-TCP/HCA (HCA: carbonate partially substituted HA). High values of mechanical properties were achieved, namely compression strength 155 MPa for the sample 0.5% h-BN/HA and Vickers microhardness of 716 HV for the samples 1.5% h-BN/HA, both sintered at 1300 degrees C. U2OS human bone osteosarcoma proliferation and cell viability showed no adverse effect in the presence of h-BN/HA, suggesting the potential use of the produced materials as safe biomaterials in bone tissue engineering. (C) 2017 Wiley Periodicals, Inc.
dc.identifier.doi10.1002/jbm.b.34046
dc.identifier.eissn1552-4981
dc.identifier.issn1552-4973
dc.identifier.pubmed29168913
dc.identifier.urihttps://hdl.handle.net/11424/235229
dc.identifier.wosWOS:000442988800030
dc.language.isoeng
dc.publisherWILEY
dc.relation.ispartofJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectcomposites
dc.subjecthydroxyapatite
dc.subjectbovine bone
dc.subjecthexagonal boron nitride
dc.subjectbioceramic
dc.subjectMECHANICAL-PROPERTIES
dc.subjectSINTERING TEMPERATURE
dc.subjectAPATITE
dc.subjectNANOPARTICLES
dc.subjectNANOTUBES
dc.subjectBHA
dc.titleSynthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride
dc.typearticle
dspace.entity.typePublication
local.avesis.id7d3f75cd-21d2-4109-a14a-f236b5e9ac3b
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages9
local.journal.quartileQ2
oaire.citation.endPage2392
oaire.citation.issue6
oaire.citation.startPage2384
oaire.citation.titleJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
oaire.citation.volume106
relation.isAuthorOfPublication5ba0a0e0-ebae-43a6-855c-0aabb90021f4
relation.isAuthorOfPublication.latestForDiscovery5ba0a0e0-ebae-43a6-855c-0aabb90021f4

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