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Other risk factors associated with mortality in moderate and severe cystic fibrosis patients

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dc.contributor.authorKARADAĞ, BÜLENT TANER
dc.contributor.authorsGokdemir, Yasemin; Erdem, Ela; Akpinar, Ihsan Nuri; Ersu, Refika; Karadag, Bulent; Karakoc, Fazilet
dc.date.accessioned2022-03-14T09:58:55Z
dc.date.available2022-03-14T09:58:55Z
dc.date.issued2012-12-15
dc.description.abstractAim: Severe pulmonary disease is responsible for over 80% of deaths associated with cystic fibrosis. Our aim was to evaluate the other risk factors associated with mortality in patients with cystic fibrosis who have moderate and severe lung disease. Material and Method: Among 200 patients with cystic fibrosis who were followed up in our clinic, 35 patients with moderate and severe lung disease (%FEV1 predicted <= 60) were included in the study. Demographic data, pulmonary function tests, high resolution thorax tomography, modified Bhalla score, blood gas analysis and nutritional status of the patients were evaluated. Results: Requirement for respiratory support was 31.4% in moderate and severe lung disease. Lower pulmonary function, requirement for non invasive ventilation, presence of diabetes mellitus, a SaO(2) value of <95, a value of pCO(2) >50 mm Hg and requirement for frequent IV antibiotics were significantly related with increased mortality. Conclusions: This is a single centre study conducted in patients with cystic fibrosis who had moderate and severe lung disease and who had not received lung transplantation. We evaluated the clinical outcome and other factors that were associated with mortality. (Turk Arch Ped 2012; 47:267-71)
dc.identifier.doi10.4274/tpa.901
dc.identifier.eissn1308-6278
dc.identifier.issn1306-0015
dc.identifier.urihttps://hdl.handle.net/11424/243814
dc.identifier.wosWOS:000313235200008
dc.language.isotur
dc.publisherTURKISH PEDIATRICS ASSOC
dc.relation.ispartofTURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChild
dc.subjectcystic fibrosis
dc.subjectrisk of mortality
dc.subjectLUNG TRANSPLANTATION
dc.subjectPSEUDOMONAS-AERUGINOSA
dc.subjectTURKISH
dc.subjectMUTATIONS
dc.subjectCHILDREN
dc.subjectPREDICTORS
dc.subjectSURVIVAL
dc.titleOther risk factors associated with mortality in moderate and severe cystic fibrosis patients
dc.typearticle
dspace.entity.typePublication
local.avesis.id703dcd52-1021-4c4f-95d9-ffae8c6bc359
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atTRDIZIN
local.journal.numberofpages5
oaire.citation.endPage271
oaire.citation.issue4
oaire.citation.startPage267
oaire.citation.titleTURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS
oaire.citation.volume47
relation.isAuthorOfPublication218b489d-97ab-49dd-9db6-0c2a732f1999
relation.isAuthorOfPublication.latestForDiscovery218b489d-97ab-49dd-9db6-0c2a732f1999

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