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Prevalence and predictors of 25-OH vitamin D deficiency in peritoneal dialysis patients: A single center study

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dc.contributor.authorVELİOĞLU, ARZU
dc.contributor.authorTUĞCU, MURAT
dc.contributor.authorAŞICIOĞLU, EBRU
dc.contributor.authorBARUTÇU ATAŞ, DİLEK
dc.contributor.authorARIKAN, İZZET HAKKI
dc.contributor.authorsBARUTÇU ATAŞ D., VELİOĞLU A., TUĞCU M., ARIKAN İ. H., AŞICIOĞLU E.
dc.date.accessioned2023-09-12T05:30:28Z
dc.date.available2023-09-12T05:30:28Z
dc.date.issued2021-09-01
dc.description.abstractVitamin D has a critical role in bone-mineral disorders in chronic kidney disease (CKD) and its deficiency is further associated with increased cardiovascular morbidity and mortality among CKD patients. We aimed to evaluate prevalence of vitamin D deficiency and investigate the laboratory and clinical parameters associated with 25- OH vitamin D deficiency in peritoneal dialysis (PD) patients. Sixty-four (33M/31F) peritoneal dialysis patients were enrolled in this retrospective single center study. Clinical and laboratory data were obtained from patient charts. Prevalence of 25-OH vitamin D deficiency and its associations were analyzed. The patients’ mean age was 49.7±13.3 years and the mean duration of PD was 61.0±55.0 months. The mean 25-OH vitamin D level was 8.9±2.4 ng/ml and none of the patients were on 25-OH vitamin D therapy. All of the patients had lower than normal 25-OH vitamin D levels according to KDOQI guidelines. Levels of 25-OH vitamin D were deficient and insufficient in 84.4% (57.8% mild; 26.6% severe) and 15.6% of the patients, respectively. There was no association between 25-OH vitamin D levels and sex, age, BMI, duration of PD and cause of ESRD. There was a negative correlation between 25-OH vitamin D levels and uric acid and parathyroid hormone. Uric acid was an independent predictor of 25-OH vitamin D deficiency in the logistic regression analysis [OR (95%CI): 0.139 (0.029-0.667), p: 0.014]. We conclude that 25-OH vitamin D deficiency is very common in PD patients. Serum uric acid is an independent predictor of 25-OH vitamin D deficiency which should further be investigated in larger studies.
dc.identifier.citationBARUTÇU ATAŞ D., VELİOĞLU A., TUĞCU M., ARIKAN İ. H., AŞICIOĞLU E., "Prevalence and predictors of 25-OH Vitamin D deficiency in peritoneal dialysis patients: A single center study", Medicine Science, cilt.10, sa.3, ss.694-697, 2021
dc.identifier.doi10.5455/medscience.2020.11.244
dc.identifier.endpage697
dc.identifier.issn2147-0634
dc.identifier.issue3
dc.identifier.startpage694
dc.identifier.urihttp://dx.doi.org/10.5455/medscience.2020.11.244
dc.identifier.urihttps://hdl.handle.net/11424/293145
dc.identifier.volume10
dc.language.isoeng
dc.relation.ispartofMedicine Science
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject25-hydroxyvitamin D
dc.subjectparathyroid hormone
dc.subjectperitoneal dialysis
dc.subjecturic acid
dc.subjectvitamin D deficiency
dc.titlePrevalence and predictors of 25-OH vitamin D deficiency in peritoneal dialysis patients: A single center study
dc.typearticle
dspace.entity.typePublication
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