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Chemical Composition and In Vitro Biological Activity of Two Thymus L. Varieties Growing in Turkey

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dc.contributor.authorTAŞKIN, TURGUT
dc.contributor.authorRAYAMAN, ERKAN
dc.contributor.authorYILMAZ, BEYZA NUR
dc.contributor.authorsTAŞKIN T., Öksüz M., Bulkurcuoğlu B., Ercelen S., RAYAMAN E., Ermanoğlu M., YILMAZ B. N., Taşkın D., Şahin T., Kılıç Ö.
dc.date.accessioned2024-04-16T12:26:16Z
dc.date.available2024-04-16T12:26:16Z
dc.date.issued2024-01-01
dc.description.abstractThymus kotschyanus var. kotschyanus (TKK) and T. kotschyanus var. glabrescens (TKG) varieties were used as both spice and medicine by the people in Turkey. It was determined that plants’ methanol extracts had the strongest antioxidant, anticholinesterase, antiurease activity and high total phenolic contents. The ethyl acetate and methanol extracts were found to have strong antimicrobial activity. Methanol extracts showed low hemolytic effect against human erythrocytes. It was determined that TKG extract showed higher anti-proliferative effect compared to TKK extract. Both plants extract significantly decreased reactive oxygen species (ROS) generation in cancer cells. It was determined that amounts of chlorogenic and rosmarinic acid compounds were similar in both plants, but apigenin 7-O-neohesperidoside compound was found in higher amounts in TKK. The findings obtained in this study suggest that methanol and ethyl acetate extracts obtained from these two species can be used as antioxidant, anticholinesterase, antimicrobial and antiurease agents. The findings support the traditional use of these species.
dc.identifier.citationTAŞKIN T., Öksüz M., Bulkurcuoğlu B., Ercelen S., RAYAMAN E., Ermanoğlu M., YILMAZ B. N., Taşkın D., Şahin T., Kılıç Ö., "Chemical Composition and In Vitro Biological Activity of Two Thymus L. Varieties Growing in Turkey", Acta Chimica Slovenica, cilt.71, sa.1, ss.9-19, 2024
dc.identifier.doi10.17344/acsi.2023.8314
dc.identifier.endpage19
dc.identifier.issn1318-0207
dc.identifier.issue1
dc.identifier.startpage9
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85189531154&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/296606
dc.identifier.volume71
dc.language.isoeng
dc.relation.ispartofActa Chimica Slovenica
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIP, GENEL & DAHİLİ
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectMEDICINE, GENERAL & INTERNAL
dc.subjectGenel Tıp
dc.subjectGeneral Medicine
dc.subjectbiological activity
dc.subjectHPLC-DAD
dc.subjectThymus species
dc.titleChemical Composition and In Vitro Biological Activity of Two Thymus L. Varieties Growing in Turkey
dc.typearticle
dspace.entity.typePublication
local.avesis.idbcd3be01-fc46-4e7b-8ab7-d6c5eadd6792
local.indexed.atSCOPUS
relation.isAuthorOfPublication265414e9-485c-42b8-903a-c467f6b49b84
relation.isAuthorOfPublication0f89f9f8-5aa4-40cc-a61f-030fd5328d19
relation.isAuthorOfPublicatione5f1d847-363c-4979-9582-c47842854ae0
relation.isAuthorOfPublication.latestForDiscovery265414e9-485c-42b8-903a-c467f6b49b84

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