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In vitro biological activities of different extracts from alcea dissecta

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dc.contributor.authorTAŞKIN, TURGUT
dc.contributor.authorDOĞAN, AHMET
dc.contributor.authorsTAŞKIN T., Kahvecioglu D., Turkoglu E. A., DOĞAN A., Kuzu M.
dc.date.accessioned2023-05-02T08:15:50Z
dc.date.available2023-05-02T08:15:50Z
dc.date.issued2022-03-01
dc.description.abstractObjective: Alcea genus belongs to Malvaceae family and this genus is represented by 85 taxa in the world and 21 taxa in the Flora of Turkey. The flowers of Alcea genus contain plenty of mucilage and are used for the treatment of respiratory diseases such as asthma and cough. Alcea dissecta is known as ‘Govik, Hiro, Hero’ in Turkey, and the flowers and leaves of this species have been used in the treatment of asthma, injury, colds, and gastrointestinal diseases in Turkey. To the best of our knowledge, there is no report on the effect of extraction methods on the biological activity of this plant. In addition, although this species is being used as a medical plant, there is no study of the antioxidant, antiurease, esterase, and anticholinesterase activity of the plant. Therefore, the aim of this study was to evaluate in vitro antioxidant, anti-urease, esterase, anticholinesterase activities of Alcea dissecta using a variety of extracts. Methods: The antioxidant activities of different extracts were examined by DPPH, ABTS, FRAP, and CUPRAC methods. The total phenolic compounds contained in the extracts were determined using the Folin-Ciocalteu reagent (FCR) method. Anti-urease and anticholinesterase activities of different extracts were evaluated by indophenol and Ellman methods respectively. In addition, esterase activities of plant extracts were determined. Results: In the present study, ethanol:water (1:1, v/v) and chloroform extracts obtained maceration method showed stronger DPPH and ABTS radical scavenging activity than other extracts. The chloroform extract obtained Soxhlet method was found to have higher FRAP and CUPRAC values than other extracts. It was also found that the ethanol extract obtained maceration method showed the most potent anti-urease and anticholinesterase activity. According to the results, the strongest inhibitory effect on both hCA I and II isoenzymes was shown by the petroleum ether extract obtained Soxhlet method. Conclusion: As a result, it was determined that different plant extracts have antioxidant, anti-urease, esterase, anticholinesterase activities. In addition, the data obtained from this study will shed light on future research on the biological activities of this species.
dc.identifier.citationTAŞKIN T., Kahvecioglu D., Turkoglu E. A., DOĞAN A., Kuzu M., "In vitro Biological Activities of Different Extracts from Alcea dissecta", CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.12, sa.1, ss.53-60, 2022
dc.identifier.doi10.33808/clinexphealthsci.787845
dc.identifier.endpage60
dc.identifier.issn2459-1459
dc.identifier.issue1
dc.identifier.startpage53
dc.identifier.urihttps://avesis.marmara.edu.tr/api/publication/dca45124-55c0-4d1b-8a43-620b4da7f5de/file
dc.identifier.urihttps://hdl.handle.net/11424/289026
dc.identifier.volume12
dc.language.isoeng
dc.relation.ispartofCLINICAL AND EXPERIMENTAL HEALTH SCIENCES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectTıbbi Ekoloji ve Hidroklimatoloji
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectInternal Medicine Sciences
dc.subjectMedical Ecology and Hydroclimatology
dc.subjectTIP, ARAŞTIRMA VE DENEYSEL
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectMEDICINE, RESEARCH & EXPERIMENTAL
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectReviews and References (medical)
dc.subjectResearch and Theory
dc.subjectAlcea dissecta
dc.subjectbiological activity
dc.subjectmedicinal plant
dc.subjectANHYDRASE INHIBITORY PROPERTIES
dc.subjectCARBONIC-ANHYDRASE
dc.subjectANTIOXIDANT ACTIVITY
dc.subjectHELICOBACTER-PYLORI
dc.subjectMEDICINAL-PLANTS
dc.subjectACETYLCHOLINESTERASE
dc.subjectDERIVATIVES
dc.subjectCAPACITY
dc.subjectFLOWER
dc.subjectAlcea dissecta
dc.subjectbiological activity
dc.subjectmedicinal plant
dc.titleIn vitro biological activities of different extracts from alcea dissecta
dc.typearticle
dspace.entity.typePublication
local.avesis.iddca45124-55c0-4d1b-8a43-620b4da7f5de
local.indexed.atWOS
relation.isAuthorOfPublication265414e9-485c-42b8-903a-c467f6b49b84
relation.isAuthorOfPublication34e928c8-270a-41b3-8311-23fba8b897ed
relation.isAuthorOfPublication.latestForDiscovery265414e9-485c-42b8-903a-c467f6b49b84

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