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Co-axial electrospinning of liposomal propolis loaded gelatin-zein fibers as a potential wound healing material

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dc.contributor.authorŞAHİN, ALİ
dc.contributor.authorsKarakas C. Y., ÜSTÜNDAĞ C. B., ŞAHİN A., KARADAĞ A.
dc.date.accessioned2023-09-18T10:55:01Z
dc.date.available2023-09-18T10:55:01Z
dc.date.issued2023-01-01
dc.description.abstractIn this study, propolis extract (PE) was first encapsulated in different liposomal formulations (65–370 nm) with high encapsulation efficiency (68%–93%). The liposomal PE was further embedded in a food-grade gelatin-zein core/shell fiber by using the co-axial electrospinning method. Transmission electron and confocal laser scanning microscopy verified the structure of liposomes and their homogeneous dispersion in fibers. Scanning electron microscopy (SEM) images confirmed the smooth morphologies of core/shell liposomal fibers. The loading of PE in liposomal fibers improved both thermal (differential scanning calorimetry) and textural (elongation at break and tensile strength) properties, and the fibers loaded with more PE provided higher mucoadhesiveness. The PE-loaded fiber showed higher antimicrobial activity against Staphylococcus aureus. The incorporation of liposomal PE in fiber enhanced the viability of human skin fibroblast (HFF-1) cells. The adhesion of HFF-1 cells on fiber was demonstrated by SEM, thus PE-loaded liposomal fiber could provide an efficient platform for cell growth. The findings of this study proposed that propolis-loaded liposomal hybrid fibers produced by the co-axial method can be used as a potential wound healing material.
dc.identifier.citationKarakas C. Y., ÜSTÜNDAĞ C. B., ŞAHİN A., KARADAĞ A., "Co-axial electrospinning of liposomal propolis loaded gelatin-zein fibers as a potential wound healing material", Journal of Applied Polymer Science, 2023
dc.identifier.doi10.1002/app.54683
dc.identifier.issn0021-8995
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85170519349&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/293484
dc.language.isoeng
dc.relation.ispartofJournal of Applied Polymer Science
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectKimya
dc.subjectFizikokimya
dc.subjectPolimer Karakterizasyonu
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectChemistry
dc.subjectPhysical Chemistry
dc.subjectCharacterization of Polymers
dc.subjectNatural Sciences
dc.subjectEngineering and Technology
dc.subjectMühendislik, Bilişim ve Teknoloji (ENG)
dc.subjectTemel Bilimler (SCI)
dc.subjectMalzeme Bilimi
dc.subjectPOLİMER BİLİMİ
dc.subjectKİMYA, FİZİKSEL
dc.subjectMALZEME BİLİMİ, ÇOKDİSİPLİNLİ
dc.subjectEngineering, Computing & Technology (ENG)
dc.subjectNatural Sciences (SCI)
dc.subjectMATERIALS SCIENCE
dc.subjectCHEMISTRY
dc.subjectPOLYMER SCIENCE
dc.subjectCHEMISTRY, PHYSICAL
dc.subjectMATERIALS SCIENCE, MULTIDISCIPLINARY
dc.subjectGenel Kimya
dc.subjectFizik Bilimleri
dc.subjectYüzeyler, Kaplamalar ve Filmler
dc.subjectPolimerler ve Plastikler
dc.subjectMalzeme Kimyası
dc.subjectGeneral Chemistry
dc.subjectPhysical Sciences
dc.subjectSurfaces, Coatings and Films
dc.subjectPolymers and Plastics
dc.subjectMaterials Chemistry
dc.subjectcell adhesion
dc.subjectencapsulation
dc.subjectHFF-1
dc.subjectlecithin
dc.subjectmucoadhesion
dc.subjectnanofilm
dc.subjectcell adhesion
dc.subjectencapsulation
dc.subjectHFF-1
dc.subjectlecithin
dc.subjectmucoadhesion
dc.subjectnanofilm
dc.titleCo-axial electrospinning of liposomal propolis loaded gelatin-zein fibers as a potential wound healing material
dc.typearticle
dspace.entity.typePublication
local.avesis.id53f85b13-89bf-4819-88ee-888023b92707
local.indexed.atSCOPUS
relation.isAuthorOfPublicationdda71138-8ce4-4265-89b2-73bc94786a4f
relation.isAuthorOfPublication.latestForDiscoverydda71138-8ce4-4265-89b2-73bc94786a4f

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