Publication: A 12-month, Open Label, Multicenter Pilot Study Evaluating Fingolimod Treatment in terms of Patient Satisfaction in Relapsing Remitting Multiple Sclerosis Patients FINE Trial
dc.contributor.authors | Akman Demir, Gulsen; Turkoglu, Recai; Saip, Sabahattin; Yuceyar, Nur; Efendi, Husnu; Turan, Omer Faruk; Agan, Kadriye; Terzi, Murat; Boz, Cavit; Tuncer, Asli; Kocer, Belgin; Kasap, Mithat; Caliskan, Zeynep | |
dc.date.accessioned | 2022-03-14T10:04:47Z | |
dc.date.available | 2022-03-14T10:04:47Z | |
dc.date.issued | 2017-06-20 | |
dc.description.abstract | Introduction: To assess satisfaction and quality of life in patients with relapsing-remitting multiple sclerosis (RRMS) who were receiving fingolimod (0.5 mg/day) for 12 months as a second-line treatment after switching from injectable agents. Methods: Patients aged 18-65 years with RRMS who fulfilled the eligibility criteria were enrolled from 16 centers throughout Turkey. Treatment Satisfaction Questionnaire for Medication and 36-item Short-Form Health Survey were completed at baseline and four visits to assess patient satisfaction and quality of life. Results: Forty-two patients (62% male; mean age: 35.7 +/- 9.4 years) were eligible for inclusion. Patient satisfaction scores at the end of the study 44.7 +/- 9.9) were significantly higher than those at baseline [32.0 +/- 9.9; (p<0.001)]. The only significant increase in the quality of life survey was in the emotional aspect (p=0.019). There were 124 adverse events and none of the five serious adverse events noted was considered drugrelated. Conclusion: Large-scale comparative studies performed with disease specific quality of life instruments will allow more information on this issue. | |
dc.identifier.doi | 10.5152/npa.2017.20515 | |
dc.identifier.eissn | 1309-4866 | |
dc.identifier.issn | 1300-0667 | |
dc.identifier.pubmed | 31903032 | |
dc.identifier.uri | https://hdl.handle.net/11424/244015 | |
dc.identifier.wos | WOS:000510207600005 | |
dc.language.iso | eng | |
dc.publisher | AVES | |
dc.relation.ispartof | NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Multiple sclerosis | |
dc.subject | fingolimod | |
dc.subject | patient satisfaction | |
dc.subject | quality of life | |
dc.subject | ORAL FINGOLIMOD | |
dc.subject | INTRAMUSCULAR INTERFERON | |
dc.subject | DOUBLE-BLIND | |
dc.subject | SAFETY | |
dc.subject | THERAPIES | |
dc.subject | EFFICACY | |
dc.subject | OUTCOMES | |
dc.subject | ACETATE | |
dc.subject | PHASE-3 | |
dc.subject | SWITCH | |
dc.title | A 12-month, Open Label, Multicenter Pilot Study Evaluating Fingolimod Treatment in terms of Patient Satisfaction in Relapsing Remitting Multiple Sclerosis Patients FINE Trial | |
dc.type | article | |
dspace.entity.type | Publication | |
local.import.package | SS16 | |
local.indexed.at | WOS | |
local.indexed.at | SCOPUS | |
local.indexed.at | PUBMED | |
local.indexed.at | TRDIZIN | |
local.journal.numberofpages | 5 | |
local.journal.quartile | Q4 | |
oaire.citation.endPage | 257 | |
oaire.citation.issue | 4 | |
oaire.citation.startPage | 253 | |
oaire.citation.title | NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY | |
oaire.citation.volume | 56 |
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