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Determination of side effects and medication adherence in major depression patients utilized antidepressants

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dc.contributor.authorOKUYAN, BETÜL
dc.contributor.authorsSancar, Mesut; Duzgun, Emine; Okuyan, Betul; Deniz, Semanur; Caliskan, Mecit; Coskun, Kadir; Izzettin, Fikret Vehbi
dc.date.accessioned2022-03-14T08:22:27Z
dc.date.available2022-03-14T08:22:27Z
dc.date.issued2016-09-20
dc.description.abstractThe aim of the study is to determine side effects, and medication adherence in patients who were diagnosed with major depression utilized antidepressants. This study was conducted in outpatient psychiatry clinic between February 2013 and May 2013. 'Toronto Side Effects Scale' and 4-item Morisky-Green-Levine Medication Adherence Scale were evaluated. Fifty-six major depression patients (mean of age: 40.82 +/- 14.28 years old; male/female: 13/43) were included in this study. Patients were treated with escitalopram (46.4%), sertraline (26.8%), venlafaxine (10.7%), citalopram (8.9%) and paroxetine (7.1%). The most common side effects that patients reported were drowsiness/daytime somnolence (57.1%), dry mouth (46.4%) and increased sleep (46.4%), increased appetite (37.5%) and malaise or fatigue (30.4%). The most severity side effects that patients experienced were drowsiness/daytime somnolence (25%), increased sleep (19.6%) and decreased libido (14.3%). Only fifteen (26.8%) patients were found high adherent to their medication. It was concluded that although the frequency and severity of side effects have been found high, the percentage of patients' medication adherence has been obtained low. Patient education and monitoring regarding side effects and medication adherence providing by pharmacists would be contributed to prevent possible drug induced problems in these patients besides the routine services they are taken from outpatient clinic.
dc.identifier.doi10.12991/marupj.259895
dc.identifier.issn1309-0801
dc.identifier.urihttps://hdl.handle.net/11424/241654
dc.identifier.wosWOS:000391177500021
dc.language.isotur
dc.publisherMARMARA UNIV, FAC PHARMACY
dc.relation.ispartofMARMARA PHARMACEUTICAL JOURNAL
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDepression
dc.subjectSide Effects
dc.subjectPatient adherence
dc.subjectPHARMACIST INTERVENTION
dc.subjectOUTCOMES
dc.subjectCARE
dc.subjectIMPACT
dc.titleDetermination of side effects and medication adherence in major depression patients utilized antidepressants
dc.typearticle
dspace.entity.typePublication
local.avesis.idfa806048-5daa-4465-8e85-2b15b1295a26
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atTRDIZIN
local.journal.numberofpages6
oaire.citation.endPage182
oaire.citation.issue1
oaire.citation.startPage177
oaire.citation.titleMARMARA PHARMACEUTICAL JOURNAL
oaire.citation.volume21
relation.isAuthorOfPublicationf6e7969a-ea61-403f-8772-1a8478556223
relation.isAuthorOfPublication.latestForDiscoveryf6e7969a-ea61-403f-8772-1a8478556223

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