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3D bioprinting applications in neural tissue engineering for spinal cord injury repair

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dc.contributor.authorGÜNDÜZ, OĞUZHAN
dc.contributor.authorsBedir, Tuba; Ulag, Songul; Ustundag, Cem Bulent; Gunduz, Oguzhan
dc.date.accessioned2022-03-10T15:25:38Z
dc.date.available2022-03-10T15:25:38Z
dc.date.issued2020
dc.description.abstractSpinal cord injury (SCI) is a disease of the central nervous system (CNS) that has not yet been treated successfully. In the United States, almost 450,000 people suffer from SCI. Despite the development of many clinical treatments, therapeutics are still at an early stage for a successful bridging of damaged nerve spaces and complete recovery of nerve functions. Biomimetic 3D scaffolds have been an effective option in repairing the damaged nervous system. 3D scaffolds allow improved host tissue engraftment and new tissue development by supplying physical support to ease cell function. Recently, 3D bioprinting techniques that may easily regulate the dimension and shape of the 3D tissue scaffold and are capable of producing scaffolds with cells have attracted attention. Production of biologically more complex microstructures can be achieved by using 3D bioprinting technology. Particularly in vitro modeling of CNS tissues for in vivo transplantation is critical in the treatment of SCI. Considering the potential impact of 3D bioprinting technology on neural studies, this review focus on 3D bioprinting methods, bio-inks, and cells widely used in neural tissue engineering and the latest technological applications of bioprinting of nerve tissues for the repair of SCI are discussed.
dc.identifier.doi10.1016/j.msec.2020.110741
dc.identifier.eissn1873-0191
dc.identifier.issn0928-4931
dc.identifier.pubmed32204049
dc.identifier.urihttps://hdl.handle.net/11424/220313
dc.identifier.wosWOS:000527395900110
dc.language.isoeng
dc.publisherELSEVIER
dc.relation.ispartofMATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNeural tissue engineering
dc.subject3D bioprinting
dc.subjectScaffolds
dc.subjectStem cells
dc.subjectSpinal cord injury
dc.subjectOLFACTORY ENSHEATHING CELLS
dc.subjectSTEM-CELLS
dc.subjectBIODEGRADABLE POLYURETHANE
dc.subjectELECTROSPUN NANOFIBERS
dc.subjectPOLYETHYLENE-GLYCOL
dc.subjectHYALURONIC-ACID
dc.subjectSCAR FORMATION
dc.subjectSCAFFOLDS
dc.subjectHYDROGEL
dc.subjectDIFFERENTIATION
dc.title3D bioprinting applications in neural tissue engineering for spinal cord injury repair
dc.typereview
dspace.entity.typePublication
local.avesis.id23cb943f-3a78-4b2a-a879-1f794062b7e4
local.import.packageSS5
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber110741
local.journal.numberofpages10
local.journal.quartileQ1
oaire.citation.titleMATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
oaire.citation.volume110
relation.isAuthorOfPublicationf11e8073-bf2f-485f-9bdf-5b3a2a0bdc1f
relation.isAuthorOfPublication.latestForDiscoveryf11e8073-bf2f-485f-9bdf-5b3a2a0bdc1f

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