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COVID-19 Vaccination Scenarios: A Cost-Effectiveness Analysis for Turkey

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dc.contributor.authorSANCAR, MESUT
dc.contributor.authorsHagens, Arnold; Inkaya, Ahmet Cagkan; Yildirak, Kasirga; Sancar, Mesut; van der Schans, Jurjen; Sancar, Aylin Acar; Unal, Serhat; Postma, Maarten; Yegenoglu, Selen
dc.date.accessioned2022-03-14T09:56:48Z
dc.date.available2022-03-14T09:56:48Z
dc.date.issued2021-04-18
dc.description.abstractAs of March 2021, COVID-19 has claimed the lives of more than 2.7 million people worldwide. Vaccination has started in most countries around the world. In this study, we estimated the cost-effectiveness of strategies for COVID-19 vaccination for Turkey compared to a baseline in the absence of vaccination and imposed measures by using an enhanced SIRD (Susceptible, Infectious, Recovered, Death) model and various scenarios for the first year after vaccination. The results showed that vaccination is cost-effective from a health care perspective, with an incremental cost-effectiveness ratio (ICER) of 511 USD/QALY and 1045 USD/QALY if vaccine effectiveness on transmission is equal or reduced to only 50% of effectiveness on disease, respectively, at the 90% baseline effectiveness of the vaccine. From a societal perspective, cost savings were estimated for both scenarios. Other results further showed that the minimum required vaccine uptake to be cost-effective would be at least 30%. Sensitivity and scenario analyses, as well as the iso-ICER curves, showed that the results were quite robust and that major changes in cost-effectiveness outcomes cannot be expected. We can conclude that COVID-19 vaccination in Turkey is highly cost-effective or even cost-saving.
dc.identifier.doi10.3390/vaccines9040399
dc.identifier.eissn2076-393X
dc.identifier.pubmed33919586
dc.identifier.urihttps://hdl.handle.net/11424/243735
dc.identifier.wosWOS:000643778000001
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofVACCINES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCOVID-19
dc.subjectcost-effectiveness
dc.subjectvaccination
dc.subjectTurkey
dc.subjectdynamic modeling
dc.titleCOVID-19 Vaccination Scenarios: A Cost-Effectiveness Analysis for Turkey
dc.typearticle
dspace.entity.typePublication
local.avesis.id1dd9073b-c9b1-43f0-bf61-f6fc12e4e186
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.articlenumber399
local.journal.numberofpages19
oaire.citation.issue4
oaire.citation.titleVACCINES
oaire.citation.volume9
relation.isAuthorOfPublication87a6fc65-406c-478f-bc6d-ffaaaf1f7b31
relation.isAuthorOfPublication.latestForDiscovery87a6fc65-406c-478f-bc6d-ffaaaf1f7b31

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