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In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-beta protein

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dc.contributor.authorAKSOY, HALİL
dc.contributor.authorsAksoy, Halil; Sekerler, Turgut; Mert, Naz Mina
dc.date.accessioned2022-03-14T09:53:38Z
dc.date.available2022-03-14T09:53:38Z
dc.date.issued2021
dc.description.abstractWound healing is a process that involves biochemical processes such as inflammation and cell proliferation and is controlled by many proteins. It is known that one of the most effective factors in this process is the inhibition of GSK3-beta protein. In current study, in silico wound healing activity of the some compounds found in the tubers of Asphodelus species used as a wound healing in traditional medicine were investigated. For this purpose, the interactions between the compounds and GSK3-beta protein were studied in silico. As a result of the study, it has been determined that and stigmasterol, beta-sitosterol and emodin molecules are effective.
dc.identifier.doi10.29228/jrp.65
dc.identifier.issn2630-6344
dc.identifier.urihttps://hdl.handle.net/11424/243573
dc.identifier.wosWOS:000701782800022
dc.language.isoeng
dc.publisherMARMARA UNIV
dc.relation.ispartofJOURNAL OF RESEARCH IN PHARMACY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAsphodelus species
dc.subjectbeta-sitosterol
dc.subjectemodin
dc.subjectGSK3-beta protein
dc.subjectstigmasterol
dc.subjectwound healing activity
dc.subjectGLYCOGEN-SYNTHASE KINASE-3-BETA
dc.subjectDOCKING
dc.titleIn silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-beta protein
dc.typearticle
dspace.entity.typePublication
local.avesis.id5f68adb8-ac02-4c48-9a77-593e8b267741
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atTRDIZIN
local.journal.numberofpages8
oaire.citation.endPage754
oaire.citation.issue5
oaire.citation.startPage747
oaire.citation.titleJOURNAL OF RESEARCH IN PHARMACY
oaire.citation.volume25
relation.isAuthorOfPublication49f7efb2-a70d-4683-b7e3-ec746927265e
relation.isAuthorOfPublication.latestForDiscovery49f7efb2-a70d-4683-b7e3-ec746927265e

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