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Skin-only versus skin-plus-orbicularis resection blepharoplasty: an elaborated analysis of early- and long-term effects on corneal nerves, meibomian glands, dry eye parameters, and eyebrow position

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dc.contributor.authorDERİCİOĞLU, VOLKAN
dc.contributor.authorŞAN, BURÇİN
dc.contributor.authorSEVİK, MEHMET ORKUN
dc.contributor.authorAKKAYA TURHAN, SEMRA
dc.contributor.authorsDERİCİOĞLU V., ŞAN B., SEVİK M. O., AKKAYA TURHAN S.
dc.date.accessioned2023-10-09T12:20:59Z
dc.date.available2023-10-09T12:20:59Z
dc.date.issued2023-09-01
dc.description.abstractPurpose: To evaluate the early- and long-term effects of 2 different blepharoplasty techniques on corneal nerves, meibomian gland morphology, clinical parameters of dry eye disease (DED), and eyebrow position. Methods: This prospective, interventional study included age-sex-matched blepharoplasty patients who had a skin-only resection (24 eyes of 12 patients; Group-S) or a skin-plus-orbicularis muscle resection (24 eyes of 12 patients; Group-M) procedure. Preoperative and postoperative parameters of in vivo corneal confocal microscopy (IVCCM; corneal nerve fiber density [CNFD], nerve branch density [CNBD], and nerve fiber length), meibomian gland area loss (MGAL), DED (Schirmer I test and noninvasive tear breakup time), and eyebrow heights (lateral [LBH] and central [CBH]) were evaluated and compared between the intervention groups (ClinicalTrials.gov, NCT05528016). Results: Compared with baseline, the CNBD of Group-S (19.91 ± 7.66 vs. 16.05 ± 7.28 branches/mm2, p = 0.049) and CNFD of Group-M (19.52 ± 7.45 vs. 16.80 ± 6.95 fibers/mm2, p = 0.028) was significantly decreased at postoperative first week. However, in both groups, IVCCM parameters returned to baseline values at postoperative first month and first year (p > 0.05). A significant MGAL increase was observed in Group-S (18.47 ± 5.43 vs. 19.94 ± 5.31, p = 0.030) and Group-M (18.86 ± 7.06 vs. 20.12 ± 7.01, p = 0.023) at the postoperative first year, demonstrating meibomian gland atrophy. Only significant changes were observed in Group-M in LBH (16.17 ± 2.45 vs. 16.67 ± 2.28 mm, p = 0.044) and CBH (17.33 ± 2.35 vs. 17.96 ± 2.31 mm, p = 0.004) at postoperative first year. Conclusions: Blepharoplasty with or without orbicularis resection seems to have similar effects on IVCCM, DED, and MGAL parameters. However, incorporating an orbicularis muscle resection in a blepharoplasty operation could slightly elevate the eyebrow position.
dc.identifier.citationDERİCİOĞLU V., ŞAN B., SEVİK M. O., AKKAYA TURHAN S., "Skin-Only Versus Skin-Plus-Orbicularis Resection Blepharoplasty: An Elaborated Analysis of Early- and Long-Term Effects on Corneal Nerves, Meibomian Glands, Dry Eye Parameters, and Eyebrow Position", Ophthalmic Plastic and Reconstructive Surgery, cilt.39, sa.5, ss.479-486, 2023
dc.identifier.doi10.1097/iop.0000000000002376
dc.identifier.endpage486
dc.identifier.issn0740-9303
dc.identifier.issue5
dc.identifier.startpage479
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85162930602&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/294301
dc.identifier.volume39
dc.language.isoeng
dc.relation.ispartofOphthalmic Plastic and Reconstructive Surgery
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectGöz Hastalıkları ve Cerrahisi
dc.subjectSağlık Bilimleri
dc.subjectMedicine
dc.subjectSurgery Medicine Sciences
dc.subjectEye Diseases and Surgery
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectCERRAHİ
dc.subjectGÖZ HASTALIKLARI
dc.subjectClinical Medicine (MED)
dc.subjectCLINICAL MEDICINE
dc.subjectSURGERY
dc.subjectOPHTHALMOLOGY
dc.subjectCerrahi
dc.subjectOftalmoloji
dc.subjectSurgery
dc.subjectOphthalmology
dc.titleSkin-only versus skin-plus-orbicularis resection blepharoplasty: an elaborated analysis of early- and long-term effects on corneal nerves, meibomian glands, dry eye parameters, and eyebrow position
dc.typearticle
dspace.entity.typePublication
local.avesis.idad1d32f9-6d18-45a8-a110-cddf676d2aec
local.indexed.atPUBMED
local.indexed.atSCOPUS
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