Publication:
Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey

Simple item page
dc.contributor.authorDOĞAN, AHMET
dc.contributor.authorsServi, Huseyin; Sen, Ali; Servi, Esra Yildirim; Dogan, Ahmet
dc.date.accessioned2022-03-14T09:51:39Z
dc.date.available2022-03-14T09:51:39Z
dc.date.issued2021
dc.description.abstractThe chemical composition of essential oils of aerial parts of Daucus carota (DEO) and Foeniculum vulgare (FEO) was specified by GC/MS. Antidiabetic, anti-inflammatory, antioxidant, and antibacterial activities of oils were tested by alpha-glucosidase inhibitory, 5-lipoxygenase inhibitory, DPPH/ ABTS radical scavenging, and broth microdilution methods, respectively. Thirty components were identified in DEO (87.7%). Carotol (27.7%), elemicin (18.1%), and limonene (16.0%) were determined as the main compounds in DEO. Seventeen constituents were identified in FEO (100.0%). Estragole (34.0%), limonene (27.1%), and alpha-pinene (19.5%) were found as major components in FEO. Both oils displayed weak antibacterial activity against Gram-negative bacteria. However, the oils were not effective on Grampositive bacteria. DEO with IC50 values of 1359 and 1579 mu g/mL and FEO with IC50 values of 3106 and 1654 mu g/mL showed weak antioxidant activities against DPPH and ABTS radicals, respectively. DEO and FEO exhibited good antilipoxygenase activities with IC50 values of 87.24 and 58.35 mu g/mL, respectively. DEO presented significantly alpha-glucosidase inhibitory activity with an IC50 value of 44.78 mu g/mL while FEO displayed poor activity with an IC50 value of 1%7 mu g/mL. This study is the first report on the 5-lipoxygenase and alpha-glucosidase inhibitory activities of aerial parts of DEO as well as on the alpha-glucosidase inhibitory activity of aerial parts of FEO. These results indicated that DEO, which has a good antidiabetic and anti-inflammatory activity, is rich in oxygenated sesquiterpene and monoterpene. Also, it showed that FEO, which has a significant anti-inflammatory activity, is rich in monoterpene and phenylpropanoid.
dc.identifier.doi10.29228/jrp.5
dc.identifier.issn2630-6344
dc.identifier.urihttps://hdl.handle.net/11424/243356
dc.identifier.wosWOS:000629451200005
dc.language.isoeng
dc.publisherMARMARA UNIV
dc.relation.ispartofJOURNAL OF RESEARCH IN PHARMACY
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDaucus carota
dc.subjectFoeniculum vulgare
dc.subjectessential oils
dc.subjectbiological activity
dc.subjectANTIMICROBIAL ACTIVITIES
dc.subjectANTIOXIDANT ACTIVITY
dc.subjectCULTIVATED CARROTS
dc.subjectSEEDS
dc.subjectEXTRACTS
dc.subjectVARIABILITY
dc.subjectCOMPONENTS
dc.subjectCHEMOTYPE
dc.subjectAPIACEAE
dc.subjectFRUITS
dc.titleChemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey
dc.typearticle
dspace.entity.typePublication
local.avesis.id8de1f602-a4f0-4af0-9ba9-beece96a87bd
local.import.packageSS16
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atTRDIZIN
local.journal.numberofpages11
oaire.citation.endPage152
oaire.citation.issue2
oaire.citation.startPage142
oaire.citation.titleJOURNAL OF RESEARCH IN PHARMACY
oaire.citation.volume25
relation.isAuthorOfPublication34e928c8-270a-41b3-8311-23fba8b897ed
relation.isAuthorOfPublication.latestForDiscovery34e928c8-270a-41b3-8311-23fba8b897ed

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
SERVİ-Ali ŞEN-Esra YILDIRIM SERVİ - 2021 - Chemical composition and biological activities of .pdf
Size:
1.2 MB
Format:
Adobe Portable Document Format
Download

Collections

Research Outputs