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Netherton syndrome: Temporary response to dupilumab

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dc.contributor.authorSALMAN, ANDAÇ
dc.contributor.authorsAktas, Meryem; Salman, Andac; Apti Sengun, Ozlem; Comert Ozer, Elif; Hosgoren Tekin, Selcen; Akin Cakici, Ozlem; Demir, Gizem; Ergun, Tulin
dc.date.accessioned2022-03-12T22:40:46Z
dc.date.available2022-03-12T22:40:46Z
dc.date.issued2020
dc.description.abstractNetherton syndrome (NS) is an orphan disease characterized by congenital ichthyosis, hair abnormalities, and atopy, with limited treatment options. We achieved temporary improvement only during the initial 6 weeks of treatment with dupilumab, which differs from the sustained improvement observed in 2 other recently published cases. Although the clinical presentation of atopy and increased pre-allergic cytokines in NS patients suggest that dupilumab may be beneficial, larger studies are required.
dc.identifier.doi10.1111/pde.14362
dc.identifier.eissn1525-1470
dc.identifier.issn0736-8046
dc.identifier.pubmed32951242
dc.identifier.urihttps://hdl.handle.net/11424/236016
dc.identifier.wosWOS:000570888900001
dc.language.isoeng
dc.publisherWILEY
dc.relation.ispartofPEDIATRIC DERMATOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectatopic eczema
dc.subjectgenetic diseases
dc.subjectmechanisms
dc.subjectIchthyosis
dc.titleNetherton syndrome: Temporary response to dupilumab
dc.typearticle
dspace.entity.typePublication
local.avesis.id6a9af583-9884-47f8-b34e-8e0b03529889
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.indexed.atPUBMED
local.journal.numberofpages2
local.journal.quartileQ3
oaire.citation.endPage1211
oaire.citation.issue6
oaire.citation.startPage1210
oaire.citation.titlePEDIATRIC DERMATOLOGY
oaire.citation.volume37
relation.isAuthorOfPublication22ba329a-4b06-4eb1-8549-b8b32f2d766b
relation.isAuthorOfPublication.latestForDiscovery22ba329a-4b06-4eb1-8549-b8b32f2d766b

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