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Phytochemical analysis and in vitro biological activity assessment of extracts from Micromeria myrtifolia

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dc.contributor.authorŞENER, TARIK EMRE
dc.contributor.authorERÇALIK YALÇINKAYA, ŞEBNEM
dc.contributor.authorsŞENER T. E., M O., E R., M E., D T., KAYA A. M., Ö K., ERÇALIK YALÇINKAYA Ş., B Y. N., Hk E.
dc.date.accessioned2024-10-22T16:19:45Z
dc.date.available2024-10-22T16:19:45Z
dc.date.issued2024-01-01
dc.description.abstractIn this study, the antioxidant capacity, the effect on anti-acetylcholinesterase and anti-urease enzyme inhibition, and kidney stone-reducing effects of different extracts from M.myrtifolia. In addition, the phytochemical content of the bioactive methanol extract was analyzed by HPLC-DAD. The methanol extract showed strong DPPH (IC50:0.036 mg/mL) radical scavenging, Cu (II) ion (6.535 mmTroloxE) and Fe3+ (6.476 FeSO4) ion reducing antioxidant activity compared to other extracts. The methanol extract contained the highest amount of phenolic (400 mgGAE) and flavonoid (2.519 QuE) compounds. Moreover, the methanol extract had significant anticholinesterase (78.935%), anti-urease (71.014%) and calcium oxalate anti-crystallization (18.22%, 37.427%) activities. The findings show that all extracts exhibited varying amounts of antibacterial activity against Staphylococcus aureus. The bioactive methanol extract contained rosmarinic acid (31.35 µg), quercetin (12.99 µg) and chlorogenic acid (3.55 µg). The analyzed compounds are thought to contribute significantly to the pharmacological effect of the methanol extract.
dc.identifier.citationŞENER T. E., M O., E R., M E., D T., KAYA A. M., Ö K., ERÇALIK YALÇINKAYA Ş., B Y. N., Hk E., "Phytochemical analysis and in vitro biological activity assessment of extracts from Micromeria myrtifolia", International Journal of Environmental Health Research, 2024
dc.identifier.doi10.1080/09603123.2024.2409829
dc.identifier.issn0960-3123
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85205600029&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/298113
dc.language.isoeng
dc.relation.ispartofInternational Journal of Environmental Health Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEczacılık
dc.subjectMeslek Bilimleri
dc.subjectFarmasötik Toksikoloji
dc.subjectSosyal ve Beşeri Bilimler
dc.subjectSosyoloji
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectPharmacology and Therapeutics
dc.subjectProfessional Sciences
dc.subjectPharmaceutical Toxicology
dc.subjectSocial Sciences and Humanities
dc.subjectSociology
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectEngineering and Technology
dc.subjectMühendislik Bilişim Ve Teknoloji (Eng)
dc.subjectYaşam Bilimleri (Life)
dc.subjectSosyal Bilimler (Soc)
dc.subjectMühendislik
dc.subjectFarmakoloji Ve Toksikoloji
dc.subjectSosyal Bilimler Genel
dc.subjectMühendislik Çevre
dc.subjectToksikoloji
dc.subjectKamu Çevre Ve İş Sağlığı
dc.subjectEngineering Computing & Technology (Eng)
dc.subjectLife Sciences (Life)
dc.subjectSocial Sciences (Soc)
dc.subjectEngineering
dc.subjectPharmacology & Toxicology
dc.subjectSocial Sciences General
dc.subjectEngineering Environmental
dc.subjectToxicology
dc.subjectPublic Environmental & Occupational Health
dc.subjectKirlilik
dc.subjectFizik Bilimleri
dc.subjectHalk, Çevre ve İş Sağlığı
dc.subjectSağlık, Toksikoloji ve Mutajenez
dc.subjectPollution
dc.subjectPhysical Sciences
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectHealth, Toxicology and Mutagenesis
dc.subjectbiological activity
dc.subjectHPLC-DAD
dc.subjectMicromeria myrtifolia
dc.titlePhytochemical analysis and in vitro biological activity assessment of extracts from Micromeria myrtifolia
dc.typearticle
dspace.entity.typePublication
local.avesis.id8e467625-4163-403f-9c30-5c3c2e74a306
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication5ff4af68-b410-4de6-be8b-a4a80167107e
relation.isAuthorOfPublicatione8ab273d-4051-422b-92d8-0623875ed172
relation.isAuthorOfPublication.latestForDiscovery5ff4af68-b410-4de6-be8b-a4a80167107e

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