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Phytochemical screening and evaluation of antioxidant, enzyme inhibition, anti-proliferative and calcium oxalate anti-crystallization activities of Micromeria fruticosa spp. brachycalyx and Rhus coriaria

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dc.contributor.authorŞENKARDEŞ, İSMAİL
dc.contributor.authorsTaskin, Turgut; Dogan, Murat; Yilmaz, Beyza Nur; Senkardes, Ismail
dc.date.accessioned2022-03-12T22:41:18Z
dc.date.available2022-03-12T22:41:18Z
dc.date.issued2020
dc.description.abstractMicromeria fruticosa spp. brachycalyx species (Lamiaceae) is used as a spice and flavoring agent. Rhus coriaria (Sumac) is widely used both spice and medicinally. In this study, antioxidant, anti-urease, anticholinesterase, anti-proliferative and calcium oxalate anti-crystallization activities of different extracts from M. fruticosa spp. brachycalyx aerial parts and R. coriaria leaves were investigated. Besides, the phytochemical content of these species was analyzed qualitatively and quantitatively. R. coriaria methanol extract showed stronger antioxidant (DPPH, FRAP, CUPRAC, ARTS) and anticholinesterase (46.85%) activity than M. fruticosa spp. brachycalyx extracts. M. fruticosa spp. brachycalyx methanol extract was found to have the highest anti-urease (11.39%) and anti-proliferative (MCF-7: 53.51%) potential. It was observed that the methanol extracts of both plants had a significant inhibition effect on calcium oxalate crystallization. R. coriaria methanol extract was determined to contain high amounts of total flavonoids (0.177 mgQE/mg extract) and tannins (0.365 mg TAE/mg extract) contents. The extracts from both plants have no cytotoxic effects on the healthy cell (L-929) and have strong biological activities in parallel with traditional use, suggesting that these plants may be used as natural sources in the future.
dc.identifier.doi10.1016/j.bcab.2020.101670
dc.identifier.eissn1878-8181
dc.identifier.urihttps://hdl.handle.net/11424/236096
dc.identifier.wosWOS:000561869500007
dc.language.isoeng
dc.publisherELSEVIER
dc.relation.ispartofBIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectM. fruticosa spp. brachycalyx
dc.subjectR.coriaria
dc.subjectPhytochemical contents
dc.subjectBiological activity
dc.subjectESSENTIAL OIL
dc.subjectL.
dc.subjectEXTRACT
dc.subjectOSTEOPONTIN
dc.subjectPOLYPHENOLS
dc.subjectCAPACITY
dc.subjectGROWTH
dc.titlePhytochemical screening and evaluation of antioxidant, enzyme inhibition, anti-proliferative and calcium oxalate anti-crystallization activities of Micromeria fruticosa spp. brachycalyx and Rhus coriaria
dc.typearticle
dspace.entity.typePublication
local.avesis.id9bb007bb-87a5-42e1-829d-4e71b1413f17
local.import.packageSS17
local.indexed.atWOS
local.indexed.atSCOPUS
local.journal.articlenumber101670
local.journal.numberofpages7
oaire.citation.titleBIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
oaire.citation.volume27
relation.isAuthorOfPublication3e59035c-d7b1-4887-b78c-2a9bc207de05
relation.isAuthorOfPublication.latestForDiscovery3e59035c-d7b1-4887-b78c-2a9bc207de05

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