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Browsing Akademik Arşiv / Academic Archive by Author "ABDULLAYEV, RUSLAN"
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Publication Open Access Analgesia Nociception Index: assessment of acute postoperative pain(ELSEVIER SCIENCE INC, 2019-07) ABDULLAYEV, RUSLAN; Abdullayev, Ruslan; Uludag, Oznur; Celik, BulentBackground and objectives: Patient self-rating based scales such as Numerical Rating Scale, Visual Analog Scale that is used for postoperative pain assessment may be problematic in geriatric or critically ill patients with communication problems. A method capable of the assessment of pain in objective manner has been searched for years. Analgesia nociception index, which is based on electrocardiographic data reflecting parasympathetic activity, has been proposed for this. In this study we aimed to investigate the effectiveness of analgesia nociception index as a tool for acute postoperative pain assessment. Our hypothesis was that analgesia nociception index may have good correlation with Numerical Rating Scale values. Methods: A total of 120 patients of American Society of Anesthesiologists (ASA) physical status I and II undergoing any surgical procedure under halogenated-based anesthesia with fentanyl or remifentanil were enrolled for the study. At the 15th minute of arrival to the Postoperative Care Unit the patients' pain was rated on a 0-10 point Numerical Rating Scale. The patients' heart rate, blood pressure, and analgesia nociception index scores were simultaneously measured at that time. The correlation between analgesia nociception index, heart rate, blood pressure and Numerical Rating Scale was examined. Results: The study was completed with 107 patients, of which 46 were males (43%). Mean (SD) analgesia nociception index values were significantly higher in patients with initial Numerical Rating Scale < 3, compared with Numerical Rating Scale <= 3 (69.1 [13.4] vs. 58.1 [12.9] respectively, p <0.001). A significant negative linear relationship (r2 = -0.312, p= 0.001) was observed between analgesia nociception index and Numerical Rating Scale. Conclusion: Analgesia nociception index measurements at postoperative period after volatile agent and opioid-based anesthesia correlate well with subjective Numerical Rating Scale scores. (C) 2019 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda.Publication Open Access Analgesia Nociception Index: Heart Rate Variability Analysis of Emotional Status(CUREUS INC, 2019-04-02) ABDULLAYEV, RUSLAN; Abdullayev, Ruslan; Yildirim, Ercan; Celik, Bulent; Sarica, Leyla TopcuBackground Analgesia nociception index (ANI) has been developed for real-time pain measurement during a surgical procedure under general anesthesia. The index is based on heart rate variability and constitutes a measure of parasympathetic tone. In this paper, we hypothesized that this index could be used as a tool to investigate the process of emotional regulation of a human subject. Materials and methods Twenty adult volunteers were recruited for the study, wherein ANI response to the emotional stimulus was evaluated. An emotional stimulus was obtained through a 60-second music sound record from the song Ala Gozlerini Sevdikim Dilber, performed by the Turkish rock band Badem. ANI measurements were obtained before the song presentation (T-pre), at the end of the record presentation (T0), and each minute thereafter until the end of the five-minute observation (T1-T5). Results Twenty participants were investigated; 10 males and 10 females. The mean age of the participants was 17.0 +/- 0.9 (min: 16, max: 20). ANI measurements were significantly lower in T0 and T3 compared with T-pre = 0.009). The differences between other values were not statistically significant. Conclusion ANI can be used for assessment of parasympathetic changes related to the emotional state of conscious patients.Publication Open Access Caudal Anesthesia for Pediatric Subumbilical Surgery, Less Load on the Postoperative Recovery Unit(CUREUS INC, 2019-03-30) ABDULLAYEV, RUSLAN; Abdullayev, Ruslan; Sabuncu, Ulku; Uludag, Oznur; Kusderci, Hatice Selcuk; Oterkus, Mesut; Buyrukcan, Aysel; Duran, Mehmet; Bulbul, Mehmet; Apaydin, Hasan Ogunc; Aksoy, Nail; Abes, MusaIntroduction Caudal epidural anesthesia, when used as a sole method for surgical anesthesia, has favorable effects on the recovery duration and the time spent in the recovery unit. In this study we made a retrospective analysis of pediatric surgery operations under local, regional and general anesthesia. We aimed to find shorter postoperative recovery times with local and regional anesthesia. Materials and method Data of the pediatric patients undergone subumbilical surgery during the two-year period in Pediatric Surgery clinic were collected. The patients' age, sex, surgery type, anesthesia and airway control routes, as well as duration of anesthesia, operation and recovery were obtained. Results Data of 937 patients were analyzed, of whom 811 (86.6%) were males. Caudal anesthesia was performed in 240 patients (25.6%) and the mean age of these patients was 3.83 +/- 3.00 years. The patients with caudal and local anesthesia spent significantly less time in the postoperative recovery unit, compared with general anesthesia groups (P < 0.001). Conclusion Caudal anesthesia as a sole method for pediatric subumbilical surgery is a relatively safe method. Patients having operation under caudal anesthesia have faster discharge times from postoperative recovery units, compared with general anesthesia. This probably reduces recovery unit expenditures.Publication Open Access Continuous hemoglobin measurement during frontal advancement operations can improve patient outcomes(2022-12-01) SARAÇOĞLU, AYTEN; ABDULLAYEV, RUSLAN; SAÇAK, BÜLENT; AYKAÇ, ZEYNEP ZUHAL; SAKAR, MUSTAFA; Saraçoğlu A., Abdullayev R., Sakar M., Saçak B., Incekoy F. G., Aykac Z.Massive hemorrhage in pediatric cranioplasty operations may necessitate blood transfusion, which may cause many complications. Radical-7 Pulse CO-Oximeter (Massimo Corporation, Irvine, CA) can provide continuous hemoglobin concentration (SpHb) measurements noninvasively. In this study, we aimed to evaluate the effects of SpHb measurement on perioperative transfusion management and postoperative patient outcomes. For this retrospective case-control study, we collected the data of pediatric patients undergoing fronto-orbital advancement surgery for plagiocephaly and trigonocephaly between 2018 and 2021. Perioperative SpHb monitoring was performed for patients in the SpHb Group. Other patients that were managed conventionally were considered as the control group (C Group). The data on patients\" demographic and clinical characteristics, intraoperative hemodynamic and laboratory variables such as blood gases, intraoperative blood losses, the amount of the transfused blood products, the length of postoperative intensive care unit (ICU) stay, and the duration of hospital stay were collected. The data of 42 patients were collected, and 29 of these patients were males (69%). In 16 of the patients, SpHb monitoring was performed. The demographic, clinical, and perioperative hemodynamic characteristics of the patients were comparable between the groups. Compared to the C Group, the SpHb Group had significantly lower perioperative packed red blood cell (PRBC) transfusion (136.3 +/- 40.1 vs. 181.5 +/- 74.8 mL, P = 0.015), less postoperative drainage (125.3 +/- 47.7 vs. 185.8 +/- 97.6 mL, P = 0.013), and shorter ICU stay (37.1 +/- 12.0 vs. 64.8 +/- 24.9 h, P < 0.001). There was a positive correlation between the amount of PRBC transfusion and the length of ICU stay (r = 0.459, P = 0.003). Patients with perioperative continuous SpHb measurement have lower intraoperative PRBC transfusion, less postoperative bleeding, and shorter ICU stay. When necessary, SpHb, together with clinical judgment and laboratory confirmation, can be used in decision-making for perioperative PRBC transfusion.Publication Open Access Cytokine Adsorption in Critically Ill COVID-19 Patients, a Case-Control Study(2022-09-01) ABDULLAYEV, RUSLAN; BİLGİLİ, BELİZ; SEVEN, SEDA; CİNEL, İSMAİL HAKKI; GÜL, FETHİ; Abdullayev R., Gül F., Bilgili B., Seven S., Cinel I.Aim: New coronavirus disease (COVID-19) has become an international emergency. As many of the intensive care unit (ICU) patients with the disease also present multiple organ failure, blood purification techniques might be a good choice in their treatment. In this study we aimed to investigate the role of cytokine removal in COVID-19 patients managed in ICUs. Methods: For this case-control study we have investigated the role of the cytokine removal by means of two resin membranes (HA330 and Mediasorb) in COVID-19 patients managed in ICUs. Particularly, we investigated the overtime variation in clinical severity scores, laboratory variables, and effects on hospital and ICU stay and mortality. Results: Seventy-two patients have been evaluated, of which half constituted Cytokine Filtration (CF) Group, and other half the Case-Control (CC) Group. Mortality was 55.6% and 50% in CF and CC groups, respectively. In the CF Group, there was decrease in C-reactive protein (CRP) and fibrinogen levels measured at the end of cytokine adsorption; lymphocyte count and ratio were increased, whereas neutrophile ratio was decreased. There were no differences between the groups regarding other laboratory variables, SOFA scores and vasopressor uses. Conclusions: We have demonstrated decrease in CRP, fibrinogen and increase in lymphocyte count in the patients having cytokine adsorption, but there was no clinical reflection of these benefits, and no decrease in mortality as well. Even though there is physio-pathologic rationale to use cytokine adsorption techniques for immunomodulation in critically ill COVID-19 patients, it is early to make strong suggestions about their benefits.Publication Open Access Perioperative hypothermia and associated factors: A prospective cohort study(2023-01-01) ABDULLAYEV, RUSLAN; UMUROĞLU, TÜMAY; Kelleci Y., ABDULLAYEV R., Cakmak G., Ozdemir H., UMUROĞLU T., Saracoglu A.Objective: Perioperative hypothermia is deleterious with many consequences, including coagulopathy, decreased immune functions, prolonged drug clearance, and cardiovascular complications. In this study we aimed to demonstrate the incidence of perioperative hypothermia during general anesthesia, its associated risk factors, and outcomes. Methods: For this prospective cohort study patients aged 18-75 years with American Society of Anesthesiologists physical status I-III scheduled for any elective operation under general anesthesia in a one-month period were recruited. The patients’ body temperatures were measured in the preoperative unit, in the operating theatre before induction, at the second hour of the operation, at the end of the operation, at the postoperative recovery unit admission, and discharge using a medical infrared thermometer. The patients’ demographic and hemodynamic characteristics, magnitudes of surgery, surgery and anesthesia durations, warming methods, hospital and Intensive Care Unit (ICU) length of stays were recorded. Results: Sixty five out of 290 enrolled patients (22.4%) developed perioperative hypothermia. Anesthesia and surgery time was longer in patients with hypothermia (p<0.001). Hospital length of stay of the patients was also longer in the patients with hypothermia (p<0.001). Intensive care unit admission of the patients with hypothermia was significantly higher compared with those with normothermia (2.7 vs 9.2%, p=0.030). Conclusion: Perioperative hypothermia continues to be a challenge despite many published clinical application guidelines in this context. Intermediate and major type surgeries resulted in more perioperative hypothermia. Perioperative hypothermia was significantly associated with longer operation and anesthesia durations, hospital length of stays, and higher ICU admissions as well. Routine monitoring and active warming should be performed throughout the perioperative period to prevent hypothermia and current practice guidelines should be followed.Publication Metadata only Postoperatif Ağrı Tedavisi Kılavuzu(2021-01-01) ABDULLAYEV, RUSLAN