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ERASLAN, MUHSİN

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2013 - 20204
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Author: ÇELİKER ATABERK, HANDE × Has files: false ×

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    Increased serum sialic acid in diabetic retinopathy of type 1 diabetes
    (2013) YAVUZ, DİLEK; Eraslan M., Yenice O., Kazokoglu H., Yavuz D.G., Cerman E., Celiker H.
    AIM: To investigate the potential association between serum sialic acid and diabetic retinopathy and its several grades. METHODS: We studied the level of serum sialic acid in 70 patients. Thirty control vs 40 type 1 diabetics and with different levels of diabetic retinopathy as well. RESULTS: We found higher levels of serum sialic acid level in diabetics compared to control subjects (95.95±9.5 vs 45.05±19.91 mmoL/L, P=0.0001). We also observed a progressive rise in its concentration as the level of diabetic retinopathy increased (P<0.05) but the correlation was weak. Serum sialic acid level correlated positively with blood glucose level (r=0.67, P=0.0001). CONCLUSION: Increase in serum sialic acid levels seems to be related to the stage of the retinopathy and may help us to determine the extent of retinopathy in type 1 diabetic patients. But we think that we need more detailed studies to get a more precise conclusion.
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    Screening for Retinopathy of Prematurity in a Tertiary Ophthalmology Department in Turkey: Incidence, Outcomes, and Risk Factors
    (SLACK INC, 2014) ÇERMAN, EREN; Cerman, Eren; Balci, Sevcan Yildiz; Yenice, Ozlem Sahin; Kazokoglu, Haluk; Celiker, Hande; Eraslan, Muhsin
    BACKGROUND AND OBJECTIVE: The aim of this study is to determine the incidence of retinopathy of prematurity (ROP), the number of preterm infants requiring treatment for ROP, and the factors influencing the development of ROP requiring treatment in a Turkish population. PATIENTS AND METHODS: Data on 1,252 infants who were screened for ROP in an ophthalmology department were retrospectively reviewed. Infants with a gestational age (GA) of no more than 28 weeks (n = 157) were designated group 1, those between 29 and 32 weeks (n = 572) were assigned to group 2, and those between 33 and 37 weeks (n = 523) were assigned to group 3. RESULTS: In group 1, ROP was detected in 70.0% of infants, 17.8% of whom required therapy. In group 2, ROP was detected in 41.4%, and 4.0% of those required therapy. In group 3, 18.1% were diagnosed with ROP, with 0.8% requiring treatment. CONCLUSION: Retinopathy of prematurity occurs, even among more mature infants, at a frequency that merits astute screening within parameters that reflect socioeconomic differences that appear to have an effect on the incidence.
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    Authors' response: evaluation of choroidal thickness among patients with oculocutaneous albinism
    (2014) ÇERMAN, EREN; Karabas, Levent; Esen, Fehim; Celiker, Hande; Elcioglu, Nursel; Cerman, Eren; Eraslan, Muhsin; Kazokoglu, Haluk; Sahin, Ozlem
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    Diurnal Spikes of Intraocular Pressure in Uveitic Glaucoma: A 24-hour Intraocular Pressure Monitoring Study
    (TAYLOR & FRANCIS INC, 2020) ÇERMAN, EREN; Esen, Fehim; Eraslan, Muhsin; Cerman, Eren; Celiker, Hande; Kazokoglu, Haluk
    Purpose The aim of this study was to document diurnal changes in intraocular pressure (IOP) in uveitic glaucoma (UG) and compare it with primary open angle glaucoma (POAG) patients. Methods Eight patients with UG and seven patients with POAG were included in this study. The patients were matched for age, gender, and glaucoma medications. None of the patients experienced angle closure, uveitis attack, and ocular surgery, and were not under steroid or immunomodulatory therapy within the last three months. The 24-hour IOP fluctuations were recorded with the help of a contact lens sensor (Sensimed Triggerfish (R), Switzerland). The diurnal IOP fluctuations were modeled with best-fit lines and statistical comparisons between the longitudinal responses of the two groups were determined with nonlinear regression. Results The comparison of mean 24-hour contact lens sensor (CLS) amplitudes revealed a significant difference between the fluctuation levels of UG and POAG groups (213 +/- 160 millivolt equivalents (mVeq) vs. 162 +/- 168 mVeq, respectivelyp= .003). The top level of the best-fit curves was significantly higher in the UG group (266 +/- 143 mVeq) compared to the POAG group (159 +/- 162 mVeq,p< .001). Both curves had their top levels between 5:00 PM and 8:00 AM. The longitudinal regression analysis revealed that the amplitudes of the 24-hour fluctuation waves were significantly different (p= .041). Conclusions This study demonstrated for the first time that the diurnal variation in IOP was significantly higher in UG patients. This difference was also more distinct between 5:00 PM and 8:00 AM clock-hours. The uveitis and glaucoma specialists should consider this potential for higher IOP fluctuations, while tailoring the glaucoma treatment in uveitic patients.