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ERASLAN, MUHSİN

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Author: DERİCİOĞLU, VOLKAN × Has files: false ×

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    Multicenter case series of standalone XEN implant vs. combination with phacoemulsification in Turkish patients
    (SPRINGER, 2021) ERASLAN, MUHSİN; Eraslan, Muhsin; Ozcan, Altan Atakan; Dericioglu, Volkan; Ciloglu, Emine
    Purpose To evaluate and compare the efficacy, safety and needling timing and rates of standalone XEN implant vs. combination with phacoemulsification in Turkish patients. Methods Retrospective, multicenter study which included the data of patients, who had open angle glaucoma including primary open angle glaucoma and pseudoexfoliation glaucoma, underwent standalone XEN implantation (XEN alone) and combined surgery with phacoemulsification (XEN + Phaco) between 2016 and 2018. Results The study included 26 eyes of 24 patients in XEN alone group and 32 eyes of 30 patients in XEN + Phaco group. The mean intraocular pressure (IOP) was 23.3 +/- 6.0 mmHg and 24.4 +/- 7.4 mmHg at baseline (p = 0.838), and it reduced to 16.3 +/- 3.0 mmHg and 16.4 +/- 2.3 mmHg at 12-month follow-up (p = 0.436) in XEN alone and XEN + Phaco groups, respectively (reduction: %30 and %33, P = 0.642). The mean number of medications reduced from 2.9 + 0.7 before surgery to 0.9 + 0.9 on month 12. In XEN alone and XEN + Phaco groups, the needling rates were 42.3% and 31.2% (p = 0.491), and the mean time to needling was 3.7 +/- 3.2 months and 4.9 +/- 8.0 months (p = 0.696), respectively. Hypotonia (17.2%) and hyphema (10.3%) were the most frequent complications, respectively. In XEN alone and XEN + Phaco groups, partial success was achieved in 73.1% and 71.9% of eyes when defined as IOP < 18 mmHg with any medication, respectively (p = 0.920). Conclusion The XEN implant provides significant reduction in IOP and number of medications, either standalone or combination with phacoemulsification. Both procedures need intensive postoperative care, requiring needling in approximately one-third of patients.
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    Choroidal varix elevates macula following Valsalva manoeuvre
    (BMJ PUBLISHING GROUP, 2014) ÇERMAN, EREN; Cerman, Eren; Eraslan, Muhsin; Dericioglu, Volkan; Sahin, Ozlem; Cekic, Osman; Mahmutyazicioglu, Kamran
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    Neurodegeneration in ocular and central nervous systems: optical coherence tomography study in normal-tension glaucoma and Alzheimer disease
    (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2015) ÇERMAN, EREN; Eraslan, Muhsin; Cerman, Eren; Cekic, Osman; Balci, Sevcan; Dericioglu, Volkan; Sahin, Ozlem; Suer, Devran; Chabou, Biman; Tuncer Elmaci, Emine Nese
    Background/aim: To evaluate, in vivo, the optical coherence tomography (OCT) of the retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) in patients with normal-tension glaucoma (NTG) and those with Alzheimer disease (AD) in comparison with healthy subjects. Materials and methods: This cross-sectional study included 18 patients with NTG, 20 with AD, and 20 control subjects. An ophthalmologic examination and OCT scans of both eyes were performed in all patients. Results: There was a significant reduction in peripapillary RNFL thickness and macular GCC thickness and a significant increase in the global loss volume (GLV) rate in both the NTG and AD patients when compared to the control subjects (P = 0.004, P = 0.006, P < 0.001, respectively). The statistical evaluation showed no difference in any RNFL or GCC parameters between the AD and NTG groups (P > 0.05). There was a negative correlation between disease duration and average RNFL and GCC thicknesses (r = -0.350, P = 0.027 and r = -0.471, P = 0.002, respectively) and a positive correlation between duration and GLV (r = 0.427, P = 0.006) in the AD group. Conclusion: The average RNFL thickness, GCC thickness, and GLV rates may help in the diagnosis of AD as an additional examination and may provide some important clues about the duration of the disease.