Person: SARI, İBRAHİM
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SARI
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İBRAHİM
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Publication Open Access Asymptomatic ST segment elevation in the recovery phase of the exercise stress test due to slow coronary flow(TERMEDIA PUBLISHING HOUSE LTD, 2014) SARI, İBRAHİM; Sunbul, Murat; Erdogan, Okan; Sari, IbrahimExercise-induced ST segment elevation without Q wave formation is rarely observed. Frequent causes are significant coronary stenosis, myocardial bridge and coronary vasospasm. Both exercise-induced ST segment elevation due to stow coronary flow and ST segment elevation in the recovery phase of the exercise stress test are very rare. We present a 49-year-old man with asymptomatic inferolateral ST segment elevation in the recovery phase of the exercise stress test due to slow coronary flow, which has not been reported previously. The learning points of the present paper are as follows: a) although significant coronary stenosis, myocardial bridge and coronary vasospasm are frequent causes of exercise-induced ST segment elevation, slow coronary flow might also cause it; b) one should keep in mind that ST segment elevation might also occur in the recovery phase; and c) ST segment elevation might be asymptomatic, as in the present case.Publication Open Access Utility of Speckle Tracking Echocardiography in Asymptomatic Mild to Moderate Aortic Stenosis at Rest and During Supine Bicycle Exercise Test(ELSEVIER SCIENCE INC, 2013-10) MUTLU, BÜLENT; Sunbul, Murat; Akhundova, Aysel; Sari, Ibrahim; Erdogan, Okan; Mutlu, BulentPublication Open Access Acute Sleep Deprivation is Associated with Increased Arterial Stiffness in Healthy Young Adults(ELSEVIER SCIENCE INC, 2013-10) SARI, İBRAHİM; Sunbul, Murat; Kanar, Batur Gonenc; Durmus, Erdal; Kivrak, Tarik; Sari, IbrahimPublication Open Access Severity of Depression and Anxiety Symptoms is Associated with Increased Arterial Stiffness in Depressive Disorder Patients Undergoing Psychiatric Treatment(KURE ILETISIM GRUBU A S, 2016-09) SARI, İBRAHİM; Yanartas, Omer; Sunbul, Murat; Durmus, Erdal; Kivrak, Tarik; Senkal, Zeynep; Subasi, Nilufer; Karaer, Gulhan; Ergun, Serhat; Sari, Ibrahim; Sayar, KemalObjective: Depression and anxiety are associated with both subdinical and clinical cardiovascular disease. Endothelial dysfunction, atherosclerosis, and inflammation are some of the underlying mechanisms. Pulse wave velocity (PWV) and augmentation index (Alx) are noninvasive markers for evaluation of arterial stiffness. The aim of this study was to examine the association between arterial stiffness parameters and depression/anxiety scores in depressive patients undergoing psychiatric treatment. Methods: The study population consisted of 30 patients with depression undergoing psychiatric treatment at least 4 weeks, and 25 age and gender matched healthy controls. Depression and anxiety were assessed by self-reported scales, including the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). Measurements of arterial stiffness parameters were performed by using a Mobil-O-Graph arteriograph system, which detects signals from the brachial artery. Results: Baseline characteristics and clinical data were similar between the two groups. BDI and BAI scores were statistically significantly higher in patients with depression (p<0.001, p<0.01). PWV and Alx were statistically significantly higher in patients with depression compared to controls (6.40 +/- 1.31 m/s vs 5.51 +/- 0.41 m/s and 26.9 +/- 12.1 % vs 17.4 +/- 11.3 %, p=0.001, p=0.004, respectively). PWV and Alx positively, mildly and statistically significantly correlated with BDI and BAI scores. Conclusion: Arterial stiffness parameters were statistically significantly higher in depressive patients receiving antidepressant treatment. Moreover, arterial stiffness parameters statistically significantly correlated with BDI and BAI. Assessment of arterial stiffness parameters may be useful for early detection of cardiovascular deterioration in depressive patients undergoing antidepressant treatment.Publication Open Access Acute inferior myocardial infarction in a patient with a prosthetic aortic valve and high international normalized ratio(TERMEDIA PUBLISHING HOUSE LTD, 2014) ATAŞ, HALİL; Atas, Halil; Sari, Ibrahim; Delil, Kenan; Ileri, Cigdem; Samadov, FuadST elevation acute myocardial infarction in patients with a mechanical prosthetic valve is rare and usually due to inadequate anticoagulation. We present a case of acute inferior myocardial infarction in a patient with a prosthetic aortic valve and high international normalized ratio, which has not been reported previously.Publication Open Access Relationship between Coronary Collateral Circulation and Left Ventricular End Diastolic Pressure and Plasma Levels of N-Terminal Pro-B-Type Natriuretic Peptide in Patients with Chronic Total Occlusion(ELSEVIER SCIENCE INC, 2013-10) ATAŞ, HALİL; Samadov, Fuad; Akhundova, Aysel; Akaslan, Dursun; Atas, Halil; Sari, Ibrahim; Yesildag, OsmanPublication Open Access Comparison of Inflammatory Markers and in Hospital Clinical Course In Patients with Lead versus Non-lead Left Sided Endocarditis(ELSEVIER SCIENCE INC, 2013-10) SARI, İBRAHİM; Bozbay, Mehmet; Uyarel, Huseyin; Koroglu, Bayram; Sari, Ibrahim; Cicek, Gokhan; Ergelen, Mehmet; Ugur, Murat; Ekmekci, Ahmet; Eren, MehmetPublication Open Access Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio are Predictors of Heart Failure(ARQUIVOS BRASILEIROS CARDIOLOGIA, 2015) SARI, İBRAHİM; Durmus, Erdal; Kivrak, Tarik; Gerin, Fethullah; Sunbul, Murat; Sari, Ibrahim; Erdogan, OkanBackground: Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are inflammatory markers used as prognostic factors in various diseases. Objectives: To compare the PLR and the NLR of heart failure (HF) patients with those of age-sex matched controls, to evaluate the predictive value of those markers in detecting HF, and to demonstrate the effect of NLR and PLR on mortality in HF patients during follow-up. Methods: This study included 56 HF patients and 40 controls without HF. All subjects underwent transthoracic echocardiography to evaluate cardiac functions. The NLR and the PLR were calculated as the ratio of neutrophil count to lymphocyte count and as the ratio of platelet count to lymphocyte count, respectively. All HF patients were followed after their discharge from the hospital to evaluate mortality, cerebrovascular events, and re-hospitalization. Results: The NLR and the PLR of HF patients were significantly higher compared to those of the controls (p < 0.01). There was an inverse correlation between the NLR and the left ventricular ejection fraction of the study population (r: -0.409, p < 0.001). The best cut-off value of NLR to predict HF was 3.0, with 86.3% sensitivity and 77.5% specificity, and the best cut-off value of PLR to predict HF was 137.3, with 70% sensitivity and 60% specificity. Only NLR was an independent predictor of mortality in HF patients. A cut-off value of 5.1 for NLR can predict death in HF patients with 75% sensitivity and 62% specificity during a 12.8-month follow-up period on average. Conclusions: NLR and PLR were higher in HF patients than in age-sex matched controls. However, NLR and PLR were not sufficient to establish a diagnosis of HF. NLR can be used to predict mortality during the follow-up of HF patients.Publication Open Access 2016 ESC and ACC/AHA/HFSA heart failure guideline updates: Changes, similarities, differences, and unresolved isssues(TURKISH SOC CARDIOLOGY) SARI, İBRAHİM; Sari, Ibrahim; Cavusoglu, Yuksel; Temizhan, Ahmet; Yilmaz, Mehmet Birhan; Eren, MehmetPublication Open Access Increased Neutrophil/Lymphocyte Ratio in Patients with Depression is Correlated with the Severity of Depression and Cardiovascular Risk Factors(KOREAN NEUROPSYCHIATRIC ASSOC, 2016) SARI, İBRAHİM; Sunbul, Esra Aydin; Sunbul, Murat; Yanartas, Omer; Cengiz, Fatma; Bozbay, Mehmet; Sari, Ibrahim; Gulec, HuseyinObjective Chronic inflammation is associated with cardiovascular (CV) risk factors and psychiatric disorders. The neutrophil to lymphocyte ratio (NLR) has been investigated as a new biomarker for systemic inflammatory response. The aim of the study is to investigate the relation of NLR with severity of depression and CV risk factors. Methods The study population consisted of 256 patients with depressive disorder. Patients were evaluated with the Hamilton Rating Scale for Depression (HAM-D). Patients were classified into four groups according to their HAM-D score such as mild, moderate, severe, and very severe depression. Patients were also evaluated in terms of CV risk factors. Results Patients with higher HAM-D score had significantly higher NLR levels compared to patients with lower HAM-D score. Correlation analysis revealed that severity of depression was associated with NLR in depressive patients (r=0.333, p<0.001). Patients with one or more CV risk factors have significantly higher NLR levels. Correlation analysis revealed that CV risk factors were associated with NLR in depressive patients (r=0.132, p=0.034). In logistic regression analyses, NLR levels were an independent predictor of severe or very severe depression (odds ratio: 3.02, 95% confidence interval: 1.867-4.884, p<0.001). A NLR of 1.57 or higher predicted severe or very severe depression with a sensitivity of 61.4% and specificity of 61.2%. Conclusion Higher HAM-D scores are associated with higher NLR levels in depressive patients. NLR more than 1.57 was an independent predictor of severe or very severe depression. A simple, cheap white blood cell count may give an idea about the severity of depression.