Person: ATAGÜNDÜZ, MEHMET PAMİR
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ATAGÜNDÜZ
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MEHMET PAMİR
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Publication Metadata only The investigation of sacroiliitis with different imaging techniques in spondyloarthropathies(SPRINGER HEIDELBERG, 2005) ATAGÜNDÜZ, MEHMET PAMİR; Inanc, N; Atagunduz, P; Sen, F; Biren, T; Turoglu, H; Direskeneli, HPurpose: The aim of this study was to compare the value of different imaging techniques in spondyloarthropathy (SpA) patients with inflammatory low back pain. Patients and Methods: We evaluated 54 patients who fulfilled the European spondyloarthropathy classification criteria and had inflammatory low back pain. They were subdivided into two groups according to changes on plain radiography rated on a 0-4 scale according to modified New York criteria. Group A patients had at least grade-2 unilateral or bilateral changes in the sacroiliac (SI) joints, whereas group B included patients with radiologic changes not exceeding grade 0-1. Quantitative SI scintigraphy and magnetic resonance imaging (MRI) were performed to investigate the value of these techniques to the diagnosis of sacroiliitis, and the sacroiliac joint:sacrum uptake ratios were calculated. Scintiscanning was done in 80 healthy subjects to define the normal range. Results: The sensitivities of plain radiography, quantitative SI scintigraphy, and MRI were 61%, 55%, and 89%, respectively, among the patients with SpA. MRI and quantitative SI scintigraphy detected sacroiliitis in 97% and 49% of group A, respectively. In group B, these results were 76% and 66%, respectively. Conclusion: Magnetic resonance imaging is the most sensitive method for detecting acute or chronic changes in SpA patients with histories of inflammatory low back pain and normal or indeterminate findings on plain radiographs.Publication Metadata only Predictors and the optimal duration of sustained remission in rheumatoid arthritis(SPRINGER LONDON LTD, 2019) ATAGÜNDÜZ, MEHMET PAMİR; Yilmaz-Oner, Sibel; Gazel, Ummugulsum; Can, Meryem; Atagunduz, Pamir; Direskeneli, Haner; Inanc, NevsunObjective To determine predictors and optimal duration of sustained remission (SR) in patients with rheumatoid arthritis (RA). Methods A total of 428 consecutive patients with RA visiting our clinic routinely between 2012 and 2013 were evaluated. Seventy seven of these patients in DAS28 remission were enrolled and followed up for 62.2 +/- 9.9 months. Patients in remission >= 6 months (SR) and shorter (non: N-SR) were compared in terms of demographic-clinical data and the psychosocial factors. At enrollment, 1st and 5th years, patients in DAS28, SDAI, and Boolean remission were determined. Results Sixty three patients were in SR and 14 in N-SR. Lower baseline DAS28 and HAQ scores, anti-CCP were positive predictors of SR. Although the presence of anxiety, depression, fibromyalgia, and fatigue were lower in the SR group, there was no significance. Patients in DAS28 remission (100%) at baseline reduced to 64% at 1st and 42.6% at 5th years. Patients satisfying SDAI and Boolean remission at these three visits were 49%, 44%, and 32.4% vs 41%, 28%, and 20.6%, respectively. If the duration of remission is defined as 6 months, the remission rates of SDAI at inclusion and fifth years' visits were similar but Boolean remission rates differed significantly and if it is accepted as >= 12 months, both the SDAI and Boolean remission rates were not different. Conclusion Low DAS28 and HAQ scores at baseline, anti-CCP were positive predictors of SR. Instead of 6 months, remission duration for >= 12 months would probably help us to predict SR independently from the chosen criteria; Boolean or SDAI.