Person: YILDIRIM, HATİCE SELİN
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YILDIRIM
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HATİCE SELİN
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Publication Open Access Osteocalcin and cross‑linked C‑terminal telopeptide of type I collagen in gingival crevicular fluid during piezocision accelerated orthodontic tooth movement: A randomized split‑mouth study(2023-04-01) YILDIRIM, HATİCE SELİN; KURU, LEYLA; Yıldırım H. S., Ateş M., Oktay Gün I., Kuru B., Çakırer B., Kuru L.Background: Piezocision, a minimally invasive surgical procedure, has been used to accelerate tooth movement. Aim: The aim of this randomized split‑mouth study was to evaluate gingival crevicular fluid (GCF) osteocalcin (OC) and type I collagen cross‑linked C‑terminal telopeptide (ICTP) levels during canine distalization with and without piezocision acceleration. Material and Methods: Fifteen systemically healthy subjects (M:F 7:8, 16.27 ± 1.14 years) requiring extraction of maxillary first premolars before retraction of canines were included in the study. Piezocisions were randomly carried out on one of the maxillary canines while bilateral canines served as controls. Canine distalization was conducted using closed‑coil springs applying a force of 150 g/side by using miniscrews as anchorage. GCF sampling was performed from maxillary canine mesial and distal sites at baseline, 1, 7, 14, and 28 days. The GCF levels of OC and ICTP were detected by enzyme-linked immunosorbent assay (ELISA). The rate of tooth movement was evaluated at 2‑week intervals. Results: The amounts of canine distalization from baseline to 14 and 28 days in the piezocision group were significantly higher than the control group (P < 0.05). The GCF OC level of the piezocision group on the tension side and the ICTP level of the same group on the compression side were higher than the respective sides of the control group on day 14 (P < 0.05). Conclusions: Piezocision was found to be an effective treatment procedure for accelerating canine distalization accompanied by increased levels of OC and ICTP.Keywords: ICTP, osteocalcin, piezosurgey, tooth movementPublication Metadata only İstanbul Anadolu 5. Tüketici Mahkemesi(2023-05-01) YILDIRIM, HATİCE SELİN; GÖKER KAMALI, SELİN; UĞURLU, FAYSAL; Yıldırım H. S., Göker Kamalı S., Uğurlu F.Publication Open Access Türkiye’deki diş hekimlerinin perspektifinden dentin hassasiyetinin prevalansı, etiyolojisi, tanı ve tedavi yaklaşımları: Anket çalışması(2023-05-01) YILDIRIM, HATİCE SELİN; KURU, LEYLA; Doğan Ç., Yıldırım H. S., Kuru L.GİRİŞ ve AMAÇ: Dentin hassasiyeti (DH), yetişkin popülasyonu etkileyen ve diş hekimlerinin klinikte sıklıkla karşılaştıkları ağrılı bir durumdur. Bu çalışmanın amacı, Türkiye’deki diş hekimlerinin DH hakkındaki görüş, davranış ve tutumlarını anket aracılığıyla değerlendirmektir.YÖNTEM ve GEREÇLER: Önceki çalışmalardan Türkçe’ye çevrilerek düzenlenen 27 soruyu içeren bu anket, Survey Monkey programında oluşturuldu. Türk Diş Hekimleri Birliği’ne kayıtlı diş hekimlerine e-posta yoluyla gönderilen anketi 217 katılımcı eksiksiz yanıtladı. Veriler tanımlayıcı istatistik, ki-kare ve Fisher exact test kullanılarak analiz edildi.BULGULAR: Hekimlerin %58.06’sı uyguladıkları tedaviler içinde DH tedavisi oranının %10’dan az ve %70.97’si kliniklerine DH şikayeti ile başvuran hastaların sıklıkla 30-39 yaş aralığında olduğunu bildirdi. Hekimlerin %64.52’sinin, hassasiyetin dentin tübüllerindeki sıvı akışı nedeniyle sinirlerin uyarılmasından kaynaklandığını düşündüğü ve %93.03’ünün hava ile uyarma yöntemiyle tanı koyduğu saptandı. Hekimler, hassasiyet tedavisinde en çok zemin hazırlayıcı faktörlerin giderilmesi (%89.40) ve evde hassasiyet giderici ajanların uygulanması (%88.48) seçeneklerini tercih ettiler. Zemin hazırlayıcı faktörlerin giderilmesi, flor verniği, periodontal cerrahi işlemler ve lazer uzman hekimler tarafından istatistiksel olarak anlamlı daha fazla uygulanmaktaydı (p<0.05). Meslekte geçirdiği süre 10 yıldan az olan hekimler, daha tecrübeli hekimlere kıyasla daha çok hassasiyet giderici ajan önermekte ve rezin uygulamaktaydılar (p<0.05). Tedavi sonrası şikayetlerin genellikle 1 hafta içinde geçtiği ve %96.77 oranında nüks ile karşılaşıldığı belirtildi.TARTIŞMA ve SONUÇ: Sonuç olarak, ankete katılan Türkiye’deki diş hekimlerinin çoğunluğunun DH hakkında güncel bilgilere sahip olduğu görülmekle birlikte, hekimler DH tedavisinin başarılı ve uzun süreli sağlanamadığını belirtmişlerdir. Bu çalışma DH’nin ülkemizde çalışan diş hekimleri tarafından hala çözülmesi zor bir sorun olarak görüldüğünü ortaya koymaktadır.Publication Metadata only Periodontolojide postoperatif Ağrı(Türkiye Klinikleri Yayınevi, 2023-03-01) KURU, LEYLA; YILDIRIM, HATİCE SELİN; Kuru L., Yıldırım H. S.ÖZET Periodontal tedavi işlemleri sırasında veya sonrasında hastalarda ağrı, rahatsızlık ve dentin hassasiyetiduyabileceği beklentisi vardır. Periodontal tedavinin en yaygın uygulanan ve ilk basamağı olandiş yüzeyi temizliği ve kök yüzeyi düzleştirmesi prosedüründe, belirli bir süre hafif ağrı duyulabilmektedir.Periodontal cerrahi tedavilerde ise daha şiddetli ağrı ve rahatsızlık hissi oluşabilmektedir. Ağrıtüm periodontal cerrahi uygulamalarının kaçınılmaz doğal bir sonucudur. Yapılan tüm periodontal tedaviişlemlerinde, hasta konforu ve memnuniyetini artırmak, hastanın tedaviye uyumunu ve iş birliğini sağlamakiçin işlemler sırasında ve sonrasında duyulan ağrıyı azaltmak büyük önem taşımaktadır. Periodontaltedavinin başarısı sadece uygun cerrahi tekniğin seçilmesi ve uygulanmasına değil aynı zamandaağrı başta olmak üzere postoperatif komplikasyonların önlenmesi ve kontrolüne de bağlıdır.Anah tar Ke li me ler: Periodontal hastalıklar; oral cerrahi işlemler; postoperatif ağrıABS TRACT During and following several periodontal procedures, it is normal for patients to experiencediscomfort, postoperative pain, and dentin hypersensitivity. The scaling and root planing procedure,which is the most frequently used treatment and first step of periodontal therapy, may causediscomfort lasting for a short time. Periodontal surgical therapy results in more severe pain and discomfort.Pain is an inevitable outcome of all periodontal surgical procedures. Therefore, it is crucial tolessen the postoperative pain of the patient in order to improve overall level of comfort and satisfaction,promote collaboration and treatment compliance. In addition to application of the proper surgical technique,the effectiveness of periodontal surgery depends on prevention and management of pain and otherpostoperative complications.Keywords: Periodontal diseases; oral surgical procedures; postoperative painPublication Metadata only Comparison of Oral Health Outcomes and Treatment Recevied in İntellectually Disabled Age Groups: A Comparative Study(2023-05-12) BERKEL, GÜLCAN; BAYRAM, FERİT; YILDIRIM, HATİCE SELİN; Güngör F., Berkel G., Bayram F., Yıldırım H. S.Publication Metadata only Clinical effect of quadrant-wise non-surgical periodontal treatment on patients with stage III grade B and C periodontitis(2023-07-01) YILDIRIM, HATİCE SELİN; Kirmaci S., YILDIRIM H. S.Objective: The aim of this study was to evaluate clinical effects of quadrant-wise non-surgical periodontal treatment in patients with stage-III grade-B and grade-C periodontitis. Methods: Forty-five non-smoker individuals who were systemically healthy, including 15 peri-odontally healthy, 15 stage-III grade-B periodontitis participant, and 15 stage-III grade-C peri-odontitis participant, were involved in this study. At baseline, plaque index, gingival index, probing depth, clinical attachment level, and bleeding on probing were evaluated for all participants, and in periodontitis groups, probing depth measurements were categorized as intermediate (4-6 mm) and deep (>6 mm), and the percentages of all categorized probing depths were calcu-lated. Quadrant-wise non-surgical periodontal treatment was performed in both periodontitis groups, and clinical measurements were performed again 1 and 3 months after quadrant-wise non-surgical periodontal treatment. Results: At baseline, periodontitis was higher in stage-III grade-C group than stage-III grade-B group (P .05). All clinical parameters improved from baseline to 1 and 3 months in all periodontitis groups (P >.05). The reduction of percentage of the regions with probing depth of 4-6 mm from baseline to 3 months was higher in stage-III grade-B group than stage-III grade-C group (P <.05). As compared to the stage-III grade-B group at 1 and 3 months, the percentage of sites with probing depth ≥ 5 mm and BOP+(%) was higher in the stage-III grade-C group (P <.05). Conclusion: According to residual probing depth and deep periodontal pockets, the clinical response of quadrant-wise non-surgical periodontal treatment was superior in stage-III grade-B periodontitis group than stage-III grade-C periodontitis group, and there was a need for periodontal surgical treatment after quadrant-wise non-surgical periodontal treatment in the stage-III grade-C periodontitis group.Publication Open Access Chewing difficulties, oral health, and nutritional status in adults with intellectual disabilities: A cross‐sectional study(2024-03-01) YILDIRIM, HATİCE SELİN; İslamoğlu A. H., Berkel G., Güngörmek H. S., Aktaç Ş., Bayram F., Sabuncular G., Güneş F. E.Background: Chewing difficulty, poor oral health, inadequate and imbalanced nutrition are serious health problems in individuals with intellectual disabilities. The participants' chewing abilities, oral health and nutritional status were analysed in this study. Methods: Forty-five adult participants with intellectual disabilities were included. Anthropometric measurements, oral health assessments, chewing ability evaluations and dietary intake analyses were conducted. Results: A 56.8% of the participants were classified as overweight or obese. Teeth grinding was reported in 33.3% of the participants, while 40.0% experienced drooling. All participants with Down syndrome and 58.6% of the participants with developmental delay had chewing difficulties. Inadequate nutrient intake was observed and the fibre, vitamins B1, B3, B9, sodium, phosphorus and iron intakes were significantly lower than reference values in those with chewing difficulty (p < .05). Conclusions: Chewing difficulties were associated with lower intake of certain nutrients, highlighting the importance of addressing oral health and dietary counselling in this population.Publication Metadata only Effects of melatonin supplementation and different exercise models on cognitive function in long-term exposure to constant light in rats(2023-01-01) YILDIRIM, HATİCE SELİN; AYDIN OMAY, BANU; KASIMAY ÇAKIR, ÖZGÜR; Erol G., Dincer B. E., Calik H. N., Oksuz H., YILDIRIM H. S., Sener D., AYDIN OMAY B., KASIMAY Ö.Publication Open Access Single nucleotide polymorphisms in IL-1A RS1800587, IL-1B RS1143634 and vitamin D receptor rs731236 in stage III grade B/C periodontitis(2022-06-01) ÖZTÜRK ÖZENER, HAFİZE; ASLAN, BEGÜM; AĞRALI, ÖMER BİRKAN; ULUCAN, KORKUT; YILDIRIM, HATİCE SELİN; KURU, LEYLA; Ozener H., ASLAN B., Eken B. F., AĞRALI Ö. B., Yildrim H. S., Altunok E. C., ULUCAN K., KURU L.The purpose of the study is to determine the prevalence of interleukin (IL)-1A (rs1800587), IL-1B (rs1143634) and vitamin D receptor (VDR) (TaqI, rs731236) gene polymorphisms in the Turkish population and their association with Stage III Grade B/C periodontitis. Systemically and periodontally healthy individuals (N = 100) and Stage III Grade B/C periodontitis patients (N=100) based on clinical and radiographic examination were included in this research. Clinical attachment level, probing depth, bleeding on probing, plaque and gingival indices of the subjects were measured. Genotyping of IL-1A (rs1800587), IL-1B (rs1143634) and VDR (rs731236) polymorphisms was conducted by Real Time PCR. Allelic and genotypic distributions of IL-1A (rs1800587) gene polymorphism were not associated with periodontitis (p > 0.05). In IL-1B (rs1143634) gene polymorphism, the C allele was detected more frequently in healthy individuals compared with the periodontitis patients (p=0.045). CC genotype and C allele in VDR (rs731236) gene polymorphism was higher in periodontitis patients (p=0.031, p=0.034, respectively). In comparison with Grade B periodontitis patients and healthy subjects, CC genotype and C allele were observed more frequently in the Grade B periodontitis in terms of alleles (C/T) and genotypes for VDR (rs731236) polymorphism (p=0.024, p=0.008, respectively). This study presents that the VDR (rs731236) polymorphism are associated with enhanced susceptibility to Stage III periodontitis in the Turkish population. Furthermore, VDR (rs731236) polymorphism may be used as an identification criteria to discriminate Grade B and Grade C in Stage III periodontitis.