Person: KARADAĞ SAYGI, NAİME EVRİM
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KARADAĞ SAYGI
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NAİME EVRİM
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Publication Metadata only Morton neuroma: Comparative results of two conservative methods(AMER ORTHOPAEDIC FOOT & ANKLE SOC, INC, 2005) KARADAĞ SAYGI, NAİME EVRİM; Saygi, B; Yidirim, Y; Saygi, EK; Kara, H; Esemenli, TBackground. The initial treatment of Morton neuromas consists of conservative methods that include shoe modifications and steroid injections. The purpose of this prospective study was to compare the efficacy of these two methods to determine which is more effective as the initial treatment method. Methods: Eighty-two patients with Morton neuromas were randomly assigned to receive either footwear modification with orthoses or steroid injections as initial treatment. Outcomes were evaluated at 1 month, 6 months, and 12 months. Results: Patient satisfaction was significantly better (p < 0.01) in the group treated with steroid injections than those treated with shoe modifications at all three followup intervals. At 12-month followup, 82% of those treated with steroid injections had complete or partial relief of pain compared to 63% of those treated with footwear modifications alone. Conclusion: Steroid injections as initial treatment and shoe modifications with steroid injections at 6 months appear to give better results in Morton neuromas than shoe modifications alone, but the difference in the two groups were not statistically significant at one year followup.Publication Metadata only Bizarre parosteal osteochondromatous proliferation of the little toe(AMER PODIATRIC MED ASSN, 2006) ERZİK, CAN; Saygi, B; Karadag-Saygi, E; Erzik, C; Erkan, M; Yildirim, YA 19-year-old woman presented with pain at the lateral side of the fifth toe of her left foot, which was separated from the adjacent toe. Initial examination suggested dislocation of the fifth metatarsophalangeal joint due to a past fracture. Radiographs showed a mass arising from the proximal phalanx of the little toe, with no medullary and cortical continuity. Excisional biopsy of the mass was performed, and a histologic diagnosis of bizarre parosteal osteochondromatous proliferation of bone (Nora's lesion) was made.Publication Metadata only The effects of daily alendronate, daily calcitonin and alendronate every other day on bone mineral density in osteoporotic men(INFORMA HEALTHCARE, 2007) AKYÜZ, GÜLSEREN DERYA; Guven, Zeynep; Karadag-Saygi, Evrim; Unlu-Ozkan, Feyza; Akyuz, GulserenObjectives. Biphosphonates have been widely used in the treatment of osteoporosis, but there is not enough data on their use in men. The aim of this study is to investigate the effects of twelve months' treatment with daily 10 mg alendronate, every other day 10 mg alendronate and daily 200 IU calcitonin on bone mineral density (BMD) in men with osteoporosis. Materials and methods. 46 men with osteoporosis were randomly allocated to three groups: 15 patients in the first group received daily 10 mg alendronate and calcium (1000 mg/day), 14 patients in the second group used every other day 10 mg alendronate and calcium and 17 patients in the third group were given intranasal salmon calcitonin and calcium. At the baseline, sixth and twelfth months, BMD was measured at lumbar spine (L2-4), femoral neck and Ward's triangle zone by means of dual energy X-ray absorptiometry (LUNAR). Results. In daily and every other day alendronate and calcitonin groups there was a significant increase in BMD at lumbar spine (p = 0.004, p = 0.001, p = 0.04), but no difference at the femoral neck (p > 0.05) at the end of twelve months. When the groups were compared with each other, no significant differences in BMD levels at lumbar spine, femoral neck and Ward's triangle were found (p > 0.05).Publication Metadata only KID syndrome patient with toe walking: A case report(INFORMA HEALTHCARE, 2009) EROL, BÜLENT; Karadag-Saygi, Evrim; Ustun, Isil; Erol, Bulent; Yucelten, DenizObjective: To report on a 10-year-old boy with KID syndrome who presented with a new onset unilateral toe walking. Method: This patient's equinus contracture was evaluated clinically. The patient underwent to surgical lengthening of Achilles tendon. After the surgery, the patient was placed in a short-leg walking cast for 6 weeks and then received a rehabilitation programme involving stretching exercises. Results: Successful heel-to-toe gait was achieved in 3 weeks following surgery and rehabilitation. Conclusion: Surgical intervention and postsurgical rehabilitation may be indicated for children who present with toe walking attributed to contracture in the Achilles tendon.Publication Metadata only Early effect of nasal salmon calcitonin on the bone marker Crosslaps(SPRINGER HEIDELBERG, 2006) AKYÜZ, GÜLSEREN DERYA; Ofluoglu, D; Karadag-Saygi, E; Canbulat, C; Gunduz, OH; KUL-Panza, E; Akyuz, GThe aim of this study was to investigate the early effect of nasal salmon calcitonin on a bone-resorption marker, Crosslaps, in postmenopausal osteoporotic women. In this randomized, single-blind and placebo-controlled study we included 78 postmenopausal women with osteoporosis, between 45 and 65 years of age, with at least 5 years duration of menopause. Patients were randomly divided into two groups, the treatment and the placebo groups. Patients in the treatment group were given 100 IU day(-1)nasal salmon calcitonin, 1,000 mg day(-1)s elemental calcium, and 400 IU day(-1) vitamin D. Patients in the placebo group took only 1,000 mg day(-1)elemental calcium, and 400 IU day(-1) vitamin D. The outcome measurements were urinary deoxypyridinoline, serum alkaline phosphatase, osteocalcin, and Crosslaps. The treatment group consisted of 39 patients whose mean age was 60.4 +/- 6 years and the placebo group included 39 patients with a mean age of 60.5 +/- 4.9 years. There was no significant difference between two groups in terms of demographic characteristics. The results of bone marker measurements were analyzed statistically. Crosslaps levels in the treatment group were significantly lower (P < 0.05) than in the placebo group. Other bone marker levels at the end of the study were not significantly lower (P > 0.05) than those at baseline in both treatment and placebo groups, however. Salmon calcitonin affects bone turnover within a few months and bone-resorption markers such as Crosslaps can be used to monitor the effect of nasal salmon calcitonin in the early phase of treatment for postmenopausal osteoporosis.Publication Metadata only Evaluation of the neurosensory function of the medial meniscus in humans(W B SAUNDERS CO-ELSEVIER INC, 2005) KARADAĞ SAYGI, NAİME EVRİM; Saygi, B; Yildirim, Y; Berker, N; Ofluoglu, D; Karadag-Saygi, E; Karahan, MPurpose: Menisci are known to have receptors mainly concentrated at the anterior and posterior horns. Although they are purported to send afferent impulses to the central nervous system, this function has not been thoroughly evaluated. The purpose of the study was to investigate whether stimulation of the menisci initiates a cortical response. The reaction of the end organ to the reflex are is also evaluated. Type of Study: Prospective case series. Methods: Fourteen patients with normal medial menisci were included in the study. Different parts of the knee joint (the posterior horn and the body of the medial meniscus, the medial femoral condyle, the capsule, and the joint space) were electrically stimulated by a probe during arthroscopy. The cortical response was monitored with somatosensory-evoked potentials (SEPs). The compound muscle action potentials (CMAPs) of the semi membranosus, quadriceps, and biceps femoris muscles were also monitored with electroneuromyography (ENMG). Results: Among the stimulated parts, only the posterior horn of the meniscus produced cortical responses. No response was obtained with stimulation of the medial femoral condyle, the body of the medial meniscus, the capsule, or the joint space. Stimulation of the posterior horn of the medial meniscus produced a measurable amount of CMAP latency for the semimembranosus muscle, but not for the quadriceps and biceps femoris muscles. Conclusions: Stimulation of the posterior horn of the medial meniscus produces reproducible cortical SEPs and results in ENMG-verified response of the semimembranosus muscle where no response of the sernimembranosus muscle is detected with stimulation of the other parts of the knee. Clinical Relevance: The knowledge that only the horns of the medial meniscus have mechanoreceptors in the medial compartment of the knee helps to understand patients' signs and symptoms in medial compartment disease.