Person: OKTAR, FAİK NÜZHET
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OKTAR
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FAİK NÜZHET
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Publication Metadata only Fabrication and characterization of pla/sa/ha composite nanofiber by electrospinning for bone tissue engineering applications(2018-07-18) CESUR, SÜMEYYE; EKREN, NAZMİ; KILIÇ, OSMAN; OKTAR, FAİK NÜZHET; BİLĞİÇ ALKAYA, DİLEK; AYAZ SEYHAN, SERAP; GÜNDÜZ, OĞUZHAN; Cesur S., Ekren N., Kılıç O., Oktar F. N., Bilğiç Alkaya D., Ayaz Seyhan S., Ege Z. R., Gündüz O.Publication Metadata only Part 2: biocompatibility evaluation of hydroxyapatite-based clinoptilolite and Al2O3 composites(SPRINGER, 2017) OKTAR, FAİK NÜZHET; Kalkandelen, C.; Suleymanoglu, M.; Kuruca, S. E.; Akan, A.; Oktar, F. N.; Gunduz, O.The biocompatibility of clinoptilolite/alumina/bovine hydroxyapatite (Cp - Al2O3 - BHA) composite, at different ratio obtained by powder pressing process, were investigated studying the behavior of osteosarcoma (SAOS-2) cells. The biocompatibility was examined by means of cytotoxicity and cytocompatibility tests. The structure and morphology of bioceramic composites were studied by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) technique. The results showed that these materials have no toxic effects. The natural composite that fabricated in this study may be a promising approach for bone engineering applications.Publication Metadata only Studies on goat hydroxyapatite/commercial inert glass biocomposites(SPRINGER, 2019) OKTAR, FAİK NÜZHET; Akyurt, N.; Yetmez, M.; Oktar, F. N.In this study, mechanical properties and microstructural analysis of goat-derived hydroxyapatite/commercial inert glass biocomposites are considered in the temperature range between 1000 and 1300 degrees C. The results indicate that the best values of maximum compressive strength and microhardness are achieved in the samples sintered at 1200 degrees C for the glass in the weight of 5 and 10%. Moreover, above 1000 degrees C, decomposition of hydroxyapatite and new phase formations such as whitlockite and silicocarnotite play also a major role in the hardness and strength for goat hydroxyapatite/commercial inert glass biocomposites.Publication Metadata only Preparation and characterization of silver-doped hydroxyapatite from seashell by different methods(2018-09-08) AYAZ SEYHAN, SERAP; BİLĞİÇ ALKAYA, DİLEK; CESUR, SÜMEYYE; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; , Ayaz Seyhan S., Bilğiç Alkaya D., Öztürk B. N., Cesur S., Topsakal A., Oktar F. N., Gündüz O.Publication Metadata only Hydroxyapatıte is bıomaterıals: its chemıcal synthesıs characterızatıon shell of cypaea annulus(2018-09-08) BİLĞİÇ ALKAYA, DİLEK; AYAZ SEYHAN, SERAP; CESUR, SÜMEYYE; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; Bilğiç Alkaya D., Ayaz Seyhan S., Öztürk B. N., Cesur S., Topsakal A., Oktar F. N., Gündüz O.Publication Metadata only The natural nano-bioceramic powder production from organ pipe red coral (Tubipora musica) by a simple chemical conversion method(AUSTRALIAN CERAMIC SOCIETY, 2018) OKTAR, FAİK NÜZHET; Karacan, Ipek; Gunduz, Oguzhan; Ozyegin, L. Sevgi; Gokce, Hasan; Ben-Nissan, Besim; Akyol, Sibel; Oktar, Faik N.The marine species are especially suited for the production of bioceramic nano-powders with natural methods for their use in the biomedical field. However, there are only very limited studies regarding the production and synthesis of hydroxyapatite (HAp) and tricalcium phosphate (TCP) nanomaterials from the marine structures. The structure of coral is very unique due to its similarity to bone because their structure consists of calcium carbonate that is the precursor for the synthesis of HAp. In this research, nano-bioceramic powders were produced from the organ pipe red coral (Tubipora musica) by two different simple chemical conversion methods under two different synthesis methods rather than the common hydrothermal method. The main advantages of these two methods are that they are simple and more economical in comparison to other methods used. All samples were analyzed by X-ray diffraction (XRD) and scanning electron microscope (SEM), respectively. The size and shape of converted particles and structures were controlled by adjusting the calcination temperature and most importantly the agitation-mixing rate. According to XRD and SEM results, it can be concluded that the nano-scale monetite and other calcium phosphate powders were successfully obtained by these simple methods although retained calcium carbonate also observed due to the partial conversion.Publication Metadata only Production and Characterization of Antimicrobial Electrospun Nanofibers Containing Polyurethane, Zirconium Oxide and Zeolite(SPRINGER, 2018) OKTAR, FAİK NÜZHET; Aydogdu, Mehmet Onur; Oprea, Alexandra Elena; Trusca, Roxana; Surdu, Adrian Vasile; Ficai, Anton; Holban, Alina Maria; Iordache, Florin; Paduraru, Andrei Viorel; Filip, Diana Georgiana; Altun, Esra; Ekren, Nazmi; Oktar, Faik Nuzhet; Gunduz, OguzhanIn this study, electrospinning technique has been utilized to prepare composite nanofiber mats of polyurethane (PU)/zirconium dioxide (ZrO2) and PU/zeolite, consisted by antimicrobial properties. Tensile strength measurement test was performed for the mechanical analysis of the nanofibers. Scanning electron microscopy (SEM) were performed for displaying the morphological features of the fiber structure. XRD tests were performed for revealing the chemical structure. Antimicrobial tests were also performed to display antimicrobial effects of the produced materials. In vitro test was also performed to determine cytotoxicity and biocompatibility. The present PU/ZrO2 and PU/zeolite composite nanofibers resulted with improved mechanical properties and good antimicrobial properties against either their pure forms or other studies. Cell proliferation and viability also increased significantly with increase in zeolite and ZrO2 ratio. It is concluded that this composition provides a novel alternative as an antimicrobial material which can be suitable as a wound dressing or a coating material for various healthcare engineering applications.Publication Metadata only Preparatıon of hydroxyapatıte biomaterıals for benzoic acid delıvery from scotch bonnets seashell by microwave processing(2018-09-08) BİLĞİÇ ALKAYA, DİLEK; AYAZ SEYHAN, SERAP; CESUR, SÜMEYYE; OKTAR, FAİK NÜZHET; GÜNDÜZ, OĞUZHAN; Öztürk B. N., Bilğiç Alkaya D., Ayaz Seyhan S., Cesur S., Topsakal A., Oktar F. N., Gündüz O.Publication Metadata only Preparation and evaluation of cerium oxide-bovine hydroxyapatite composites for biomedical engineering applications(ELSEVIER SCIENCE BV, 2014) OKTAR, FAİK NÜZHET; Gunduz, O.; Gode, C.; Ahmad, Z.; Gokce, H.; Yetmez, M.; Kalkandelen, C.; Sahin, Y. M.; Oktar, F. N.The fabrication and characterization of bovine hydroxyapatite (BHA) and cerium oxide (CeO2) composites are presented. CeO2 (at varying concentrations 1, 5 and 10 wt%) were added to calcinated BHA powder. The resulting mixtures were shaped into green cylindrical samples by powder pressing (350 MPa) followed by sintering in air (1000-1300 degrees C for 4 h). Density, Vickers microhardness (HV), compression strength, scanning electron microscopy (SEM) and X-ray diffraction (XRD) studies were performed on the products. The sintering behavior, microstructural characteristics and mechanical properties were evaluated. Differences in the sintering temperature (for 1 wt% CeO2 composites) between 1200 and 1300 degrees C, show a 3.3% increase in the microhardness (564 and 582.75 HV, respectively). Composites prepared at 1300 degrees C demonstrate the greatest compression strength with comparable results for 5 and 10 wt% CeO2 content (106 and 107 MPa) which are significantly better than those for 1 wt% and those that do not include any CeO2 (90 and below 60 MPa, respectively). The results obtained suggest optimal parameters to be used in preparation of BHA and CeO2 composites, while also highlighting the potential of such materials in several biomedical engineering applications. (C) 2014 Elsevier Ltd. All rights reserved.Publication Metadata only Electrospun multilayer nanofiber based intelligent drug delivery and release system(2018-07-18) OKTAR, FAİK NÜZHET; YILMAZ, BETÜL; CESUR, SÜMEYYE; GÜNDÜZ, OĞUZHAN; Ege Z. R., Oktar F. N., Akan A., Kuruca D. S., Yılmaz B., Erdemir G., Cesur S., Gündüz O.