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AKYÜZ, GÜLSEREN DERYA

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AKYÜZ

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GÜLSEREN DERYA

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Now showing 1 - 6 of 6
  • Publication
    The relationships of motor-evoked potentials to hand dexterity, motor function, and spasticity in chronic stroke patients: a transcranial magnetic stimulation study
    (SPRINGER HEIDELBERG, 2016) AKYÜZ, GÜLSEREN DERYA; Cakar, Engin; Akyuz, Gulseren; Durmus, Oguz; Bayman, Levent; Yagci, Ilker; Karadag-Saygi, Evrim; Gunduz, Osman Hakan
    The standardization of patient evaluation and monitoring methods has a special importance in evaluating the effectiveness of therapeutic methods using drugs or rehabilitative techniques in stroke rehabilitation. The aim of this study was to investigate the relationships between clinical instruments and transcranial magnetic stimulation (TMS)-evoked neurophysiological parameters in stroke patients. This study included 22 chronic post-stroke patients who were clinically assessed using the Motricity Index (MI), finger-tapping test (FTT), Motor Activity Log (MAL) 28, Brunnstrom motor staging and Ashworth Scale (ASH). Motor-evoked potential (MEP) latency and amplitude, resting motor threshold (rMT) and central motor conduction time (CMCT) were measured with TMS. Shorter MEP-latency, shorter CMCT, higher motor-evoked potential amplitude, and diminished rMT exhibited significant correlations with clinical measures evaluating motor stage, dexterity, and daily life functionality. rMT exhibited a negative correlation with hand and lower extremity Brunnstrom stages (r = -0.64, r = -0.51, respectively), MI score (r = -0.48), FTT score (r = -0.69), and also with amount of use scale and quality of movement scale of MAL 28 scores (r = -0.61, r = -0.62, respectively). Higher MEP amplitude and diminished rMT showed positive correlations with reduced ASH score (r = -0.65, r = 0.44, respectively). The TMS-evoked neurophysiologic parameters including MEP latency, amplitude, rMT and CMCT generally have positive correlation with clinical measures which evaluate motor stage, dexterity and daily life functionality. Additionally, spasticity has also remarkable relationships with MEP amplitude and rMT. These results suggest that TMS-evoked neurophysiological parameters were useful measures for monitoring post-stroke patients.
  • Publication
    Comparison of the effectiveness of orthotic intervention, kinesiotaping, and paraffin treatments in patients with carpal tunnel syndrome: A single-blind and randomized controlled study
    (HANLEY & BELFUS-ELSEVIER INC, 2019) AKYÜZ, GÜLSEREN DERYA; Kaplan, Basak Mansiz; Akyuz, Gulseren; Kokar, Serdar; Yagci, Ilker
    Purpose: The aim of the study was to compare different conservative treatments in patients with carpal tunnel syndrome (CTS). Study Design: A single-blind randomized controlled study. Methods: Patients (n = 169) diagnosed with mild or moderate CTS were screened; 110 met study requirements. The patients were randomized into 3 groups. The control (CON) comparison provided to all patients was a fabricated night orthotic which held the wrist in a neutral position. The second group received adjunctive kinesiotaping (KIN) and the third group received paraffin (PARA). All patients were evaluated clinically, electrophysiologically, and ultrasonographically before treatment and at 3 weeks, 3 months, and 6 months. Results: There were 36 patients in CON, 37 in KIN, and 37 in PARA. Pain reduction in KIN was better than the other groups at 3 weeks (mean difference [MD] in CON 2.4 +/- 2.5, KIN 3.7 +/- 2.0, PARA 2.7 +/- 2.3; P < .01) and 6 months (MD in CON 3.4 +/- 3.0, KIN 4.9 +/- 3.1, PARA 3.7 +/- 2.9: P < .05). KIN pain reduction was better than CON at 3 months (MD in CON 3.8 +/- 2.8, KIN 5.0 +/- 2.5: P <.05). Reduction of the cross-sectional area of median nerve at the level of radioulnar joint was greater for KIN than CON at 3 weeks (MD in CON 0.0 +/- 0.5, KIN 0.3 +/- 0.7; P < .01) than PARA at 3 months (MD in KIN 0.3 +/- 0.8, PARA 0.0 +/- 0.8; P < .05) and both groups at 6 months (MD in CON 0.1 +/- 0.8, KIN 0.5 +/- 0.9, PARA 0.0 +/- 1.0 P < .05). Conclusion: Adding KIN to night use of an orthotic was more effective in achieving symptomatic and structural improvements than either the orthotic alone or adjunctive use of paraffin in patients with mild and moderate CTS. (C) 2018 Hanley & Belfus, an imprint of Elsevier Inc. All rights reserved.
  • Publication
    Hypovitaminosis D in widespread pain: its effect on pain perception, quality of life and nerve conduction studies
    (SPRINGER HEIDELBERG, 2015) AKYÜZ, GÜLSEREN DERYA; Kuru, Pinar; Akyuz, Gulseren; Yagci, Ilker; Giray, Esra
    The aim of the study was to investigate the effects of hypovitaminosis D on pain, quality of life (QoL) and nerve conduction studies (NCSs) in patients with chronic widespread pain (CWP). We randomly selected 83 female patients with CWP according to their vitamin D levels in this cross-sectional study. Patients were divided into two groups as sufficient vitamin D level (above 20 ng/ml) and deficient vitamin D level (below 20 ng/ml, hypovitaminosis D). Various pain scales and Nottingham Health Profile (NHP) were used. NCSs were also done. In patients with hypovitaminosis D, there were significantly higher pain scores for all scales (p value range 0.002-0.027). The subscale and total NHP scores were significantly higher in hypovitaminosis D group (p = 0.048-0.001) except social isolation subscale (p = 0.553). Vitamin D levels were in negative correlation with right and left median and/or ulnar motor nerve amplitudes, left tibial motor amplitude. This study confirm that hypovitaminosis D is related with higher pain intensity and lower QoL scores in patients with CWP when compared with control group. Additionally, we identified for the first time that there were negative correlations between vitamin D levels and some findings of NCSs.
  • Publication
    Bilateral Brachial Neuritis Following Diphtheria, Tetanus and Pertussis Vaccination: Case Report
    (ORTADOGU AD PRES & PUBL CO, 2010) AKYÜZ, GÜLSEREN DERYA; Yagci, Ilker; Ofluoglu, Demet; Akyuz, Gulseren
    Brachial plexopathy in children is commonly caused by obstetrical complications. Only few cases were reported as brachial neuritis which is also known as Personage Turner disease. Antecedent infection, viral diseases, trauma, surgery, and immunization may be the possible etiologic factors causing brachial neuritis. In this case report, a 6 months old child who was referred to our outpatient clinic with bilateral hand, arm and shoulder weakness which occurred after immunization with diphtheria, tetanus and pertussis (DTP) vaccine at 5 months of age is presented. The case was diagnosed as bilateral brachial neuritis according to clinical and electrophysiological data and no possible etiologic factors could be associated with the clinical condition except DTP vaccination.
  • Publication
    Challenges in the treatment of fibrodysplasia ossificans progressiva
    (SPRINGER HEIDELBERG, 2019) AKYÜZ, GÜLSEREN DERYA; Gencer-Atalay, Kardelen; Ozturk, Ekim Can; Yagci, Ilker; Ata, Pinar; Delil, Kenan; Ozgen, Zerrin; Akyuz, Gulseren
    Fibrodysplasia ossificans progressiva (FOP), is a rare autosomal dominant connective tissue disease with a prevalence of 1 in 2 million. It is characterized by congenital foot deformities and multiple heterotopic ossifications in fibrous tissue. It usually starts with painful soft tissue swellings occurring with attacks at the ages of three or four. The attacks develop spontaneously or after minor trauma, and gradually turn into heterotopic ossifications that cause joint limitations, growth defects, skeletal deformities and chronic pain. The average life expectancy is forthy, and most of the patients are lost due to pulmonary complications. FOP is often misdiagnosed as fibromatosis, desmoid tumour or cancer, bunion, myositis, arthritis and rheumatic diseases. After clinical suspicion, confirmatory genetic analysis should be used for the diagnosis. The treatment of FOP is currently supportive. An effective, proven method has not yet been established. Herein, we present an 18-year-old female patient with FOP who underwent different treatment modalities in a 5-year period. This case-based review reveals all available treatment approaches with at least 6-month follow-up for FOP in the literature.
  • Publication
    Comparative electrophysiological techniques in the diagnosis of carpal tunnel syndrome in patients with diabetic polyneuropathy
    (ELSEVIER IRELAND LTD, 2010) AKYÜZ, GÜLSEREN DERYA; Yagci, Ilker; Gunduz, Osman Hakan; Sancak, Seda; Agirman, Mehmet; Mesci, Erkan; Akyuz, Gulseren
    Objective: To determine utility of comparative electrophysiological techniques in differentiating carpal tunnel syndrome (CTS) in the background of diabetic polyneuropathy (DPN). Design: Ninety diabetic patients were classified into three groups: normal, CTS, and DPN according to nerve conduction studies (NCSs). The patients in the DPN group were divided into two subgroups of DPN and DPN-CTS according to clinical criteria. The comparative electrophysiological parameters including median-radial sensory distal latency difference (M-RSLD), median-ulnar sensory distal latency difference (M-USLD) and lumbrical-interosseous median-ulnar distal latency difference (LIMULD) were compared in subgroups of DPN, DPN-CTS and CTS. Results: Thirty-five (38.8%), 47(52.3%), and 8(8.9%) patients were diagnosed as CTS, DPN, and normal, respectively, according to NCS. After clinical stratification, 25 patients were diagnosed as DPN and 22 patients were diagnosed as DPN-CTS. The mean M-USLD and LIMULD values were similar in CTS and DPN-CTS groups, but larger than DPN statistically (p < 0.05 for all). LIMULD, M-RSLD and M-USLD were positive in 88.4, 73 and 54% in the DPN-CTS group, respectively. Conclusions: Electrophysiological abnormalities were common in diabetic patients and LIMULD can identify CTS in diabetic DPN patients better than M-RSLD and M-USLD. (C) 2010 Elsevier Ireland Ltd. All rights reserved.