Person: AKYÜZ, GÜLSEREN DERYA
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AKYÜZ
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GÜLSEREN DERYA
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Publication Metadata only The Efficacy of Tai Chi and Yoga in Rheumatoid Arthritis and Spondyloarthropathies: A narrative biomedical review(SPRINGER HEIDELBERG, 2018) AKYÜZ, GÜLSEREN DERYA; Akyuz, Gulseren; Kenis-Coskun, OzgeRheumatoid arthritis (RA) and spondyloarthropathies (SpA) are among the most common inflammatory rheumatic diseases, which might induce chronic pain for their sufferers. Mind-body interventions like Tai Chi and yoga are among the many alternative therapies for combatting chronic pain. This review aims to overview the articles about their effectiveness in RA and SpA. We searched PubMed/MEDLINE, Scopus, and Web of Science for English-language sources from their inception through September 2017. Case-control studies, interventional studies, and case series that included more than three cases and randomized crossover studies were included. The literature search retrieved 133 non-duplicate records, and 15 of them were eligible and were included in this review. The influence of Tai Chi remains debatable in RA, while there is only one study that investigated its efficacy in SpA. Yoga seems effective in decreasing pain and inflammation while increasing quality of life. There are no data available about its effect on SpA. Even after a thorough research, the number of articles is quite limited on the effectiveness of Tai Chi and yoga in RA and SpA. While these complementary approaches still show some promise as alternative therapies in RA and SpA, the literature lacks long-term studies with larger patient groups.Publication Open Access Assessment of the Relationships Between Spinopelvic Radiologic Parameters and Balance, Gait and Falls Efficacy in Patients with Postmenopausal Osteoporosis(GALENOS YAYINCILIK, 2018-12-01) AKYÜZ, GÜLSEREN DERYA; Giray, Esra; Akyuz, GulserenObjective: The aim of this study is to investigate the relationship between sagittal balance, spinopelvic parameters, bone mineral density, balance, and falls efficacy in postmenopausal osteoporosis patients. Materials and Methods: Forty patients between the ages of 40-80 with a diagnosis of postmenopausal osteoporosis were included in the study. Spinopelvic parameters (sagittal vertical axis (SVA), thoracic kyphosis, lumbar lordosis, pelvic tilt, pelvic incidence, sacral slope) were calculated from spine radiographs. Patients were applied Tinetti Balance and Gait Assessment and Falls Efficacy Scale. Relationship between bone mineral density measurements, clinical parameters, spinopelvic parameters, balance and gait, and falls efficacy were investigated. Results: Mean age of the patients was 63.42 +/- 8.98 and the mean L1-L4 T score was 2.5 +/- 0.68. Statistically significant negative correlation was found between the L1-L4 and L2-L4 vertebrae bone mineral density and T score, and sacral slope. Negative statistical correlations were found between SVA and Tinetti Balance and Gait Assessment balance subtest and total scores. There was no statistically significant relationship with other spinopelvic parameters. There was no significant correlation between SVA and spinopelvic parameters and Falls Efficacy Scale, while a statistically significant negative correlation detected between Falls Efficacy Scale and Tinetti Balance and Gait Assessment balance and gait subtests and total scores. Among the patients with normal, mild and severe deformity sagittal balance, there was statistically significant difference in terms of Tinetti Balance and Gait Assessment balance and gait subtests scores and total scores, while there was no difference with regards to Falls Efficacy Scale. Conclusion: In postmenopausal women with osteoporosis, SVA, sagittal balance parameters, and balance and gait functions were found to be associated.Publication Metadata only The relationships of motor-evoked potentials to hand dexterity, motor function, and spasticity in chronic stroke patients: a transcranial magnetic stimulation study(SPRINGER HEIDELBERG, 2016) AKYÜZ, GÜLSEREN DERYA; Cakar, Engin; Akyuz, Gulseren; Durmus, Oguz; Bayman, Levent; Yagci, Ilker; Karadag-Saygi, Evrim; Gunduz, Osman HakanThe standardization of patient evaluation and monitoring methods has a special importance in evaluating the effectiveness of therapeutic methods using drugs or rehabilitative techniques in stroke rehabilitation. The aim of this study was to investigate the relationships between clinical instruments and transcranial magnetic stimulation (TMS)-evoked neurophysiological parameters in stroke patients. This study included 22 chronic post-stroke patients who were clinically assessed using the Motricity Index (MI), finger-tapping test (FTT), Motor Activity Log (MAL) 28, Brunnstrom motor staging and Ashworth Scale (ASH). Motor-evoked potential (MEP) latency and amplitude, resting motor threshold (rMT) and central motor conduction time (CMCT) were measured with TMS. Shorter MEP-latency, shorter CMCT, higher motor-evoked potential amplitude, and diminished rMT exhibited significant correlations with clinical measures evaluating motor stage, dexterity, and daily life functionality. rMT exhibited a negative correlation with hand and lower extremity Brunnstrom stages (r = -0.64, r = -0.51, respectively), MI score (r = -0.48), FTT score (r = -0.69), and also with amount of use scale and quality of movement scale of MAL 28 scores (r = -0.61, r = -0.62, respectively). Higher MEP amplitude and diminished rMT showed positive correlations with reduced ASH score (r = -0.65, r = 0.44, respectively). The TMS-evoked neurophysiologic parameters including MEP latency, amplitude, rMT and CMCT generally have positive correlation with clinical measures which evaluate motor stage, dexterity and daily life functionality. Additionally, spasticity has also remarkable relationships with MEP amplitude and rMT. These results suggest that TMS-evoked neurophysiological parameters were useful measures for monitoring post-stroke patients.Publication Open Access Fracture History in Osteoporosis: Risk Factors and its Effect on Quality of Life(AVES, 2015-01-15) AKYÜZ, GÜLSEREN DERYA; Kuru, Pinar; Akyuz, Gulseren; Cersit, Hulya Peynirci; Celenlioglu, Alp Eren; Cumhur, Ahmet; Biricik, Sefikcan; Kozan, Seda; Goksen, Aylin; Ozdemir, Mikail; Luleci, EmelBackground: Fractures are one of the main outcomes in osteoporosis and have an important effect on the general health status. Aims: The purpose of this study was to determine the effect of major fracture history on quality of life. We also investigated the important risk factors and their effect on bone mineral density and fracture history. Study Design: Cross-sectional study. Methods: We recruited 105 patients who were admitted to an osteoporosis outpatient clinic. Medical history, family history, calcium intake, physical activity level and biochemical tests were evaluated. Lumbar spine and femur neck bone mineral density were measured. The Qualeffo-41 questionnaire was also used for evaluating quality of life. Results: The average age of the 105 patients included in the study was 56.04 +/- 13.73 and 89% of them were post-menopausal women. The average body mass index was 26.84 +/- 5.99, which means that the women were overweight. Also, 48.5% of the patients were diagnosed with osteoporosis and 51.5% of them were diagnosed as low bone density. A total of 34 patients had a fracture history with minor trauma and some of the patients had more than one fracture (12 ankle and foot, 10 forearm, 9 vertebral, 4 hand, 3 hip, 2 rib, 1 tibial). When the patients with and without fracture history were compared, the mean Qualeffo-41 score in patients with fracture was 43.85 +/- 2.57 and in the non-fracture group was 36.27 +/- 2.01. Conclusion: Forearm, ankle and foot fractures can be commonly seen in osteoporosis patients with fracture history. We suggest that it is important to recognise osteoporosis prior to first fracture and disease-specific quality of life assessment should be done.Publication Metadata only Anatomy and Assessment of the Autonomic Nervous System(AVES, 2012) AKYÜZ, GÜLSEREN DERYA; Akyuz, Gulseren; Akdeniz Leblebicier, MerveAutonomic Nervous System (ANS) is responsible for the vegetative functions of the body. It is composed of many ganglions, plexi, cerebrospinal nuclei and nerves. ANS, which is also known as visceral or vegetative nervous system, helps to control many functions, such as blood pressure, gastrointestinal motility, glands, bladder functions, sweating and body temperature. ANS innervates all the smooth muscles and the heart, and keeps to stabilize body functions within certain limits. ANS is composed of 3 components: sympathetic system (thoracolomber-adrenergic), parasympathetic system (craniosacral- cholinergic) and enteric system (nonadrenergic- noncholinergic). Autonomic nerves are classified with regard to their origin from central nervous system, the distribution of peripheral ganglions, their various physiological effects on visceral organs, and response to pharmacological agents. It is essential to know the anatomy and the physiology of the ANS, in order to evaluate disorders, achieve the correct diagnosis and to plan accurate treatment.Publication Metadata only Comparison of the effectiveness of orthotic intervention, kinesiotaping, and paraffin treatments in patients with carpal tunnel syndrome: A single-blind and randomized controlled study(HANLEY & BELFUS-ELSEVIER INC, 2019) AKYÜZ, GÜLSEREN DERYA; Kaplan, Basak Mansiz; Akyuz, Gulseren; Kokar, Serdar; Yagci, IlkerPurpose: The aim of the study was to compare different conservative treatments in patients with carpal tunnel syndrome (CTS). Study Design: A single-blind randomized controlled study. Methods: Patients (n = 169) diagnosed with mild or moderate CTS were screened; 110 met study requirements. The patients were randomized into 3 groups. The control (CON) comparison provided to all patients was a fabricated night orthotic which held the wrist in a neutral position. The second group received adjunctive kinesiotaping (KIN) and the third group received paraffin (PARA). All patients were evaluated clinically, electrophysiologically, and ultrasonographically before treatment and at 3 weeks, 3 months, and 6 months. Results: There were 36 patients in CON, 37 in KIN, and 37 in PARA. Pain reduction in KIN was better than the other groups at 3 weeks (mean difference [MD] in CON 2.4 +/- 2.5, KIN 3.7 +/- 2.0, PARA 2.7 +/- 2.3; P < .01) and 6 months (MD in CON 3.4 +/- 3.0, KIN 4.9 +/- 3.1, PARA 3.7 +/- 2.9: P < .05). KIN pain reduction was better than CON at 3 months (MD in CON 3.8 +/- 2.8, KIN 5.0 +/- 2.5: P <.05). Reduction of the cross-sectional area of median nerve at the level of radioulnar joint was greater for KIN than CON at 3 weeks (MD in CON 0.0 +/- 0.5, KIN 0.3 +/- 0.7; P < .01) than PARA at 3 months (MD in KIN 0.3 +/- 0.8, PARA 0.0 +/- 0.8; P < .05) and both groups at 6 months (MD in CON 0.1 +/- 0.8, KIN 0.5 +/- 0.9, PARA 0.0 +/- 1.0 P < .05). Conclusion: Adding KIN to night use of an orthotic was more effective in achieving symptomatic and structural improvements than either the orthotic alone or adjunctive use of paraffin in patients with mild and moderate CTS. (C) 2018 Hanley & Belfus, an imprint of Elsevier Inc. All rights reserved.Publication Metadata only The Effectiveness of Kinesiotaping, Sham Taping or Exercises Only in Lateral Epicondylitis Treatment: A Randomized Controlled Study(WILEY, 2019) AKYÜZ, GÜLSEREN DERYA; Giray, Esra; Karali-Bingul, Duygu; Akyuz, GulserenBackground: Lateral epicondylitis is a common musculoskeletal condition presenting with pain and tenderness over the lateral epicondyle and dorsal forearm, pain and weakness in gripping and limitations in daily activities. It is proposed that kinesiotaping, a new application of adhesive taping, reduces pain and improves muscle function. Objective: To compare efficacy of kinesiotaping, sham taping, or exercises only in the treatment of lateral epicondylitis. Design: Double-blind, randomized, controlled trial. Setting: Tertiary medical center, university hospital. Participants: Thirty patients with lateral epicondylitis for less than 12weeks. Methods or Interventions: Patients were randomized into three groups: kinesiotaping plus exercises (n = 10), sham taping plus exercises (n = 10), and control (exercises only) (n = 10) groups. All recipients were provided a home exercise program including strengthening and stretching exercises. In kinesiotaping and sham taping groups, tapings were performed and changed every 3-4 d for 2 weeks. Main Outcome Measure(s): The primary outcome was the patient-rated tennis elbow evaluation (PRTEE). Pain visual analogue scale (VAS), grip strength, and the disabilities of the arm, shoulder and hand (QuickDASH) scales were secondary outcomes. Evaluations were done at baseline, posttreatment, and at 4 weeks after treatment. The immediate effect was also assessed by VAS and grip strength immediately after real and sham tapings. Results: PRTEE total scores at posttreatment and at 4 weeks after treatment were statistically significantly lower in kinesiotaping plus exercises group compared to sham taping plus exercises group and exercises only group. The effects of kinesiotaping were larger than sham taping and only exercises at posttreatment (d = -1.21, d = -1.33) and at 4 weeks after treatment (d = -1.39, d = -1.34). Repeated-measures anova showed a significant interaction between the time and the groups (F 2950 = 4849; P = .006). Significant between-group differences were found in QuickDASH score and VAS at rest at 4 weeks after treatment, VAS at daily activity at posttreatment and 4 weeks after treatment when kinesiotaping plus exercises and sham taping plus exercises groups and kinesiotaping plus exercises and exercises only groups were compared. Real taping but not sham taping immediately led to an increase in grip strength, decrease in VAS at rest and VAS at daily activity (P = .0017, P = .041, P = .028; respectively). Conclusions: Kinesiotaping in addition to exercises is more effective than sham taping and exercises only in improving pain in daily activities and arm disability due to lateral epicondylitis.Publication Metadata only Comparison of Conventional Pulmonary Rehabilitation and High-Frequency Chest Wall Oscillation In Primary Ciliary Dyskinesia(WILEY-BLACKWELL, 2014) KARADAĞ, BÜLENT TANER; Gokdemir, Yasemin; Karadag-Saygi, Evrim; Erdem, Ela; Bayindir, Ozun; Ersu, Refika; Karadag, Bulent; Sekban, Nimet; Akyuz, Gulseren; Karakoc, FaziletBackgroundEnhancement of mucociliary clearance by pulmonary rehabilitation (PR) is advocated in primary ciliary dyskinesia (PCD). Our primary aim was to compare the efficacy and safety of postural drainage, percussion and vibration [conventional PR (CPR)], and high frequency chest wall oscillation (HFCWO) by studying change in pulmonary function. Our secondary aim was to evaluate patient preferences regarding the two methods. MethodsThis was a controlled randomized crossover study. PCD patients between the ages of 7 and 18 years were assigned to two groups, first group performed airway clearance with CPR at hospital for 5 days and after a 2-day washout period HFCWO was applied to the same group at home. HFCWO was applied first to the other group and then these patients were hospitalized for CPR. The primary outcome measure of the study was pulmonary function test (PFT). The secondary outcomes were pulse arterial oxygen saturation (SpO(2)) and the perceived efficiency and comfort level. ResultsPFT values of patients increased significantly after both PR methods (before/after): CPR: FVC: 77.014.1/81.8 +/- 13.0 (P=0.002); FEV1: 72.9 +/- 14.8/78.7 +/- 13.5 (P=0.001); PEF: 73.8 +/- 14.5/82.5 +/- 14.5 (P=0.001); FEF25-75: 68.6 +/- 27.6/74.9 +/- 29.3 (P=0.007). HFCWO: FVC: 75.1 +/- 15.3/80.3 +/- 13.9 (P=0.002); FEV1: 71.4 +/- 16/77.4 +/- 14.6 (P=0.001); PEF: 70.9 +/- 18.0/78.3 +/- 17.7 (P=0.002); FEF25-75: 70.5 +/- 23.4/76.4 +/- 25.6 (P=0.006). There were no significant differences in % predicted FVC, FEV1, PEF, and FEF25-75 increased values with CPR and HFCWO. HFCWO was found more comfortable (P=0.04). Two PR methods were found efficient and no desaturation occurred during PR. ConclusionsPFTs were significantly increased after both PR methods. There were no differences in PFTs and SpO(2) between the CPR and HFCWO groups. Both PR methods were found efficient. HFCWO was found more comfortable. HFCWO may be an option in patients with chronic pulmonary disease and low adherence to PR. Pediatr Pulmonol. 2014; 49:611-616. (c) 2013 Wiley Periodicals, Inc.Publication Metadata only Does the Provocation Maneuvers Increase the Sensitivity of Sensory Nerve Conduction Studies in Diagnosis of Carpal Tunnel Syndrome?(GALENOS YAYINCILIK, 2012-12-15) İŞAK, BARIŞ; Aktas, Ilknur; Sunter, Gulin; Uluc, Kayihan; Isak, Baris; Tanridag, Tulin; Akyuz, Gulseren; Us, OnderObjective: The aim of this study was to determine the sensitivity of sensory nerve conduction study (NCS) parameters in the diagnosis of carpal tunnel syndrome (CTS) and to explore if the use of provocative maneuvers improves their sensitivity Materials and Methods: In this prospective study, we included 85 consecutive cases (135 hands) that had signs and symptoms of CTS, and 100 control hands. Sensory NCS was performed in the neutral position and then the wrist was placed in flexion and 90 degrees of extension for 1 min. Onset and peak latencies and velocities, negative peak duration and area, and peak amplitude were measured. Results: The most sensitive parameters were onset latency (77%), and onset (72%) and peak velocities (72%) in neutral position. The flexion maneuver did not increase their sensitivity, however, negative peak area (10%) and amplitude (24%) sensitivities were higher in extended position than in neutral position. Conclusion: The most sensitive NCS parameters were onset latency, and onset and peak velocities in neutral position. The extension maneuver was more sensitive than neutral position. Turk J Phys Med Rehab 2012;58:307-71.Publication Metadata only Hypovitaminosis D in widespread pain: its effect on pain perception, quality of life and nerve conduction studies(SPRINGER HEIDELBERG, 2015) AKYÜZ, GÜLSEREN DERYA; Kuru, Pinar; Akyuz, Gulseren; Yagci, Ilker; Giray, EsraThe aim of the study was to investigate the effects of hypovitaminosis D on pain, quality of life (QoL) and nerve conduction studies (NCSs) in patients with chronic widespread pain (CWP). We randomly selected 83 female patients with CWP according to their vitamin D levels in this cross-sectional study. Patients were divided into two groups as sufficient vitamin D level (above 20 ng/ml) and deficient vitamin D level (below 20 ng/ml, hypovitaminosis D). Various pain scales and Nottingham Health Profile (NHP) were used. NCSs were also done. In patients with hypovitaminosis D, there were significantly higher pain scores for all scales (p value range 0.002-0.027). The subscale and total NHP scores were significantly higher in hypovitaminosis D group (p = 0.048-0.001) except social isolation subscale (p = 0.553). Vitamin D levels were in negative correlation with right and left median and/or ulnar motor nerve amplitudes, left tibial motor amplitude. This study confirm that hypovitaminosis D is related with higher pain intensity and lower QoL scores in patients with CWP when compared with control group. Additionally, we identified for the first time that there were negative correlations between vitamin D levels and some findings of NCSs.
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