Person: AKYÜZ, GÜLSEREN DERYA
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AKYÜZ
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GÜLSEREN DERYA
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Publication Open Access Can assessment of disease burden and quality of life based on mobility level in patients with end-stage cancer provide an insight into unmet needs? An exploratory cross-sectional study(2022-02-01) AKYÜZ, GÜLSEREN DERYA; Bahar-Ozdemir Y., Kaya S., Akgul-Babacan N., Al T., Albayrak E., Coskun N., Akyuz G.Purpose The purpose of this study was to: 1) investigate the differences in the needs of end-stage cancer who can move independently, using mobility aids (MA), or are bedridden; and 2) determine the effects of these different mobility levels on the patients\" current quality of life (QoL), fatigue, and mental conditions. Methods The study employed an exploratory prospective cross-sectional study design, which was carried out in two hospitals. The study included 99 end-stage cancer. The mobility levels of the patients were evaluated in three groups: Group 1: bedridden; Group 2: mobile with MA; and Group 3: ambulatory (under supervision or fully independent). A core cancer-specific questionnaire-integrating system for assessing health-related QOL (EORTC-QLQ-C15-PAL), the Piper Fatigue Scale (PFS), and the Hospital Anxiety-Depression scale were utilized. The median age was 60years (31-83). Cancer types were as follows: gastrointestinal (45.5%), lung (38.4%), breast (4%), genitourinary system (4%), and others (8%). Forty-two percent of the patients were completely bedridden, 42.2% used MA, and 15.2% were independently ambulatory. The EORTC QLQ-C15-PAL physical (=.000) and emotional function values (=.029) differed among mobilization statuses. There was a significant difference among mobilization groups, in terms of behavioral values, in the PFS (=.006). The depression rate in the independent ambulatory group was lower than in the bedridden and MA groups (=0.011; =0.004). p p p p1 p2 Conclusion Health-related QoL, fatigue level, and emotional state vary in end-stage cancer who undergo evaluations according to their mobility levels. These patients should be assessed comprehensively, and treatment plans should be organized carefully, with a multidisciplinary approach.Publication Open Access The effect of adding robot-assisted hand rehabilitation to conventional rehabilitation program following stroke: A randomized-controlled study(2022-01-01) AKYÜZ, GÜLSEREN DERYA; Bayındır O., Akyüz G., Sekban N.© 2022 All right reserved by the Turkish Society of Physical Medicine and Rehabilitation.Objectives: This study aimed to investigate the effectiveness of adding robot-assisted hand therapy (HandTutor) to conventional rehabilitation program compared to a conventional rehabilitation program alone in stroke survivors. Patients and methods: Between March 2012 and December 2012, a total of 33 stroke patients (21 males, 12 females; median age: 56 years; range, 38 to 73 years) were included in this prospective, randomized-controlled study. The patients were randomly divided into two groups as experimental (n=16) and control (n=17). Both groups received conventional rehabilitation for 3 h/day, for two days/week, totally for five weeks, while the experimental group received additional 1-hour robot-assisted hand therapy during each session. Outcome measures were the Fugl-Meyer Assessment, Box and Block Test, Nine-Hole Peg Test, Jebsen-Taylor Hand Function Test, grip strength, and pinch strength. All patients were assessed at baseline, at the end of the treatment, and three months after the treatment. Results: Both groups showed statistically significant improvements in all the parameters (p0.05). The changes between baseline and three-month follow-up after the treatment revealed that adding robot-aided hand therapy led to greater changes in all the parameters related to functional activities and muscle strength, except for the Fugl-Meyer Assessment. Conclusion: Adding robot-assisted therapy to conventional rehabilitation may provide greater changes in upper extremity rehabilitation of subacute stroke patients compared to conventional rehabilitation program alone.Publication Open Access The reliability and validity of the Turkish version of the brief pain inventory-short form in patients with cancer pain(2022-01-01) AKYÜZ, GÜLSEREN DERYA; Balta S., Ünal-Ulutatar Ç., Mirzayeva S., Başkaya M. Ç. , Akyüz G.© 2022 All right reserved by the Turkish Society of Physical Medicine and Rehabilitation.Objectives: The aim of this study was to evaluate the reliability and validity of the Turkish version of the Brief Pain Inventory (BPI-TR) in patients with cancer pain. Patients and methods: The study included 130 patients (70 females, 60 males; mean age: 56.1±13.3 years; range, 18 to 87 years) diagnosed with any type and stage of cancer between April 2017 and March 2018. Brief Pain Inventory, Pain Disability Index, EORTC QLQ C30 and Pain Management Index were used to collect data. The reliability of the scale was tested with \"internal consistency\" and its validity with \"construct validity\". Cronbach’s alpha values of >0.70 were accepted as the threshold for internal consistency. Construct validity was tested in the context of structural validity with factor analysis and also tested in terms of convergent construct validity by investigating its correlation with the Pain Disability Index (PDI) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30). Results: The internal consistency of pain severity and pain-related interference was found as 0.91 and 0.95, respectively. The alpha coefficient was found to be between 0.795 and 0.873 for the pain severity index and between 0.729 and 0.861 for the pain-related interference index. There was a clear link between the BPI-TR pain severity index and the ninth question in the EORTC QLQ-C30 (rho=0.66, p<0.05). The association between the BPI-TR interference index and the 19th question in the EORTC QLQ-C30 was also strong (rho=0.77, p<0.05). The correlation between the BPI-TR interference index and the PDI was found to be moderate (rho=0.50, p<0.05). Conclusion: The BPI-TR was found to be a reliable and legitimate tool to evaluate cancer pain in the Turkish population.