Person: KARGÜL, BETÜL
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KARGÜL
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BETÜL
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Publication Metadata only The effect of a single application of different fluoride varnishes on enamel subsurface lesions in vitro(2022-04-01) ŞEN YAVUZ, BETÜL; YILMAZ, MÜESSER AHU; OKTAY, NİHAL ŞEHKAR; KARGÜL, BETÜL; Yildiz P. K., ŞEN YAVUZ B., YILMAZ M. A., OKTAY N. Ş., KARGÜL B.This in vitro study aimed to evaluate the therapeutic effect of different fluoride ion (F) varnish formulations for controlling the carious development of enamel subsurface lesions and the F release into artificial saliva for 2 hr, 24 hr, 48 hr, and 7 days. Artificial enamel carious lesions were created and divided into 6 groups (5 varnish groups and a control group). Varnishes were applied to enamel specimens and then the specimens were incubated in artificial saliva, with the artificial saliva replenished daily. Varnish was removed and lesions were remineralized in artificial saliva for 24 hr. Surface microhardness was measured three times: (i) initially, (ii) after creating the artificial enamel lesions, and (iii) after applying the varnishes. The F release was analyzed after 2 hr, 24 hr, 48 hr, and 7 days of exposure using an ion-selective electrode. Data were analyzed using a One-way Analysis of Variance with the Tukey-Kramer Multiple Comparisons test and the Kruskal-Wallis test with the Dunns Multiple Comparisons test. The highest percentage surface microhardness recovery was found for the treatment with the MI Varnish. According to the percentage surface microhardness recovery results, a statistically significant difference was found between the varnishes and the control group (p < 0.05 and < 0.001). All varnishes released measurable levels of fluoride ions. However, the release of F was the highest in the MI Varnish group (p < 0.01). Duraphat, Enamel Pro Varnish, and MI Varnish released the most F into artificial saliva. Calcium phosphate-based F varnishes improve the capacity of the enamel surface re -hardening. CPP containing F varnish had the highest release of F as compared to the other F releasing varnishes. Further in vivo investigations are also required to prove the clinical applications of the different ingredients containing varnishes.Publication Metadata only Effect of mobile phones as a magnetic field on the microhardness of human teeth(2016-06-05) KARGÜL, BETÜL; YILMAZ, MÜESSER AHU; YAVUZ İ., AKDAĞ M. Z., DAŞDAĞ S., DURHAN M. A., KARGÜL B.To investigate the effect of radiofrequency (RF) radiation emitted from 900 MHz mobile phones on the enamel and cementum microhardness of human teeth. Methods A number of sources emit electromagnetic fields especially radiofrequencies are growing rapidly in the world we live today. A total of 32 freshly extracted human premolar teeth were prepared for the study group. A generator which produces 900 MHz radiofrequency radiation was used in this study to represent exposure of global systems for mobile communication (GSM). Teeth were exposed to the radiation for 2 h per day (7 days a week) for 12 months. Digital micro-Vickers hardness tester (Wilson Wolpert Europe BV, 401 MVD, Netherlands) fitted with a Vickers diamond and a 200 N load was used to make indentations in the enamel and cementum surfaces. Data were analysed using SPSS 16.0 software. Paired sample t test was used (p\0.05). Results The mean baseline microhardness in enamel (165.82 ± 56.63) was found to be lower than after exposure (163.80 ± 24.53). However, difference between baseline and after exposure were not found to be statistically significant (p = 0.855). The mean value of baseline cementum surface was 41.15 ± 13.81 and after radiation was 26.16 ± 8.13. There were statistically significant differences between pre- and post-radiation in cementum (p = 0.000). Conclusions Despite this result of this study, it can be considered that long term exposure of 900 MHz radiofrequencies emitted from mobile phones may decrease the microhardness of teeth.Publication Metadata only Farklı remineralizasyon ajanlarının yapay mine lezyonları üzerinde iki farklı kantitatif floresan sistemine göre etkisi(2023-07-07) ÖZSALİH BİLSEL, SEDA; KARGÜL, BETÜL; BEKİROĞLU, GÜLNAZ NURAL; YILMAZ, MÜESSER AHU; Özsalih Bilsel S., Kargül B., Doğan S., Bekiroğlu G. N., Yılmaz M. A.Publication Metadata only Viability of fibroblasts in a novel probiotic storage media(WILEY, 2010) KARGÜL, BETÜL; Caglar, E.; Sandalli, N.; Kuscu, O. O.; Durhan, M. A.; Pisiriciler, R.; Caliskan, E. Ak; Kargul, B.A number of storage media have been investigated as to their ability to maintain the viability of the periodontal ligament (PDL) cells and thus to permit longer extra-alveolar periods prior to replantation of avulsed teeth. The aim of the present in vitro study was to evaluate the number of viable PDL cells of avulsed teeth treated by Hank's Balanced Salt Solutions (HBSS), saline, a novel probiotic solution and milk. Thirty-six freshly extracted single-rooted human teeth with closed apices were divided into one of the four experimental groups and two control groups (N = 6 each). The positive and negative controls corresponded to 0 min and an 8-h dry time respectively. Following extraction, the coronal 3 mm of PDL tissue was scraped with a #15 scalpel to remove cells that might have been damaged. The experimental teeth were dried for 30 min followed by a 45 min immersion in one of the four experimental media. Each experimental tooth, after drying and soaking, was incubated for 30 min with a 2.5 ml solution of 0.2 mg ml(-1) of collagenase CLS II and a 2.4 mg ml(-1) solution of dispase grade II in phosphate buffer saline (PBS). The cells were then labelled with 0.4% Trypan blue for determination of viability. The teeth stored in positive control demonstrated the highest number of viable PDL cells followed in rank order by HBSS, saline, Lactobacillus reuteri solution and milk. There was no significant difference in the number of viable PDL cells between HBSS, milk, L. reuteri solution and saline. Within the parameters of this study, it appears that probiotic may be able to maintain PDL cell viability as HBSS, milk, or saline.Publication Metadata only Pandemi döneminde acil kliniğine gelen travma olgularının değerlendirilmesi(2021-10-07) KARGÜL, BETÜL; YILMAZ, MÜESSER AHU; kodaman n., DURHAN M. A., KARGÜL B.