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KARGÜL, BETÜL

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KARGÜL

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BETÜL

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Now showing 1 - 10 of 30
  • Publication
    The relation between laser fluorescence scores after caries removal and microtensile bond strength
    (2023-07-04) KANAR, ÖZLEM; TAĞTEKİN, DİLEK; KORKUT, BORA; KARGÜL, BETÜL; KANAR Ö., TAĞTEKİN D., KORKUT B., YANIKOĞLU F., KARGÜL B.
  • Publication
    Effect of biomimetic mineralization on demineralized dentin: a SEM/EDS analysis
    (2021-09-16) KARGÜL, BETÜL; TÜRKMEN, CAFER; atalı p., TÜRKMEN C., kukey p., KARGÜL B.
  • Publication
    The effect of a single application of different fluoride varnishes on enamel subsurface lesions in vitro
    (2022-04-01) ŞEN YAVUZ, BETÜL; YILMAZ, MÜESSER AHU; OKTAY, NİHAL ŞEHKAR; KARGÜL, BETÜL; Yildiz P. K., ŞEN YAVUZ B., YILMAZ M. A., OKTAY N. Ş., KARGÜL B.
    This in vitro study aimed to evaluate the therapeutic effect of different fluoride ion (F) varnish formulations for controlling the carious development of enamel subsurface lesions and the F release into artificial saliva for 2 hr, 24 hr, 48 hr, and 7 days. Artificial enamel carious lesions were created and divided into 6 groups (5 varnish groups and a control group). Varnishes were applied to enamel specimens and then the specimens were incubated in artificial saliva, with the artificial saliva replenished daily. Varnish was removed and lesions were remineralized in artificial saliva for 24 hr. Surface microhardness was measured three times: (i) initially, (ii) after creating the artificial enamel lesions, and (iii) after applying the varnishes. The F release was analyzed after 2 hr, 24 hr, 48 hr, and 7 days of exposure using an ion-selective electrode. Data were analyzed using a One-way Analysis of Variance with the Tukey-Kramer Multiple Comparisons test and the Kruskal-Wallis test with the Dunns Multiple Comparisons test. The highest percentage surface microhardness recovery was found for the treatment with the MI Varnish. According to the percentage surface microhardness recovery results, a statistically significant difference was found between the varnishes and the control group (p < 0.05 and < 0.001). All varnishes released measurable levels of fluoride ions. However, the release of F was the highest in the MI Varnish group (p < 0.01). Duraphat, Enamel Pro Varnish, and MI Varnish released the most F into artificial saliva. Calcium phosphate-based F varnishes improve the capacity of the enamel surface re -hardening. CPP containing F varnish had the highest release of F as compared to the other F releasing varnishes. Further in vivo investigations are also required to prove the clinical applications of the different ingredients containing varnishes.
  • Publication
    Do ginger extract, natural honey and bitter chocolate remineralize enamel surface as fluoride toothpastes? an in-vitro study
    (Wolters Kluwer Medknow Publications, 2021) KARGÜL, BETÜL; Celik Z.C., Yavlal G.O., Yanikoglu F., Kargul B., Tagtekin D., Stookey G.K., Peker S., Hayran O.
    Background: In recent literatures, much attention has been given to natural products for their health benefits. Aims: In this study, the objective was to measure the efficacy of the ginger-honey-chocolate mixture as the remineralization effect has been shown in the literature previously and to evaluate the individual contributions of this mixture; ginger, natural honey, bitter chocolate separately on remineralization of initial enamel caries lesion. Materials and Methods: All specimens were divided into eight groups as: Ginger (Arifoglu®, Turkey) in powder form, (n = 8); Ginger-Honey-Chocolate (n = 8); Natural honey (Balparmak Plateau Blossom Honey®, Turkey) (n = 9); Bitter chocolate (Nestlé®, Switzerland) (n = 8); MI Paste (GC, Japan) (n = 8); Paradontax (Sensodyne, Glaxosmithklein, USA) (n = 9); Pronamel (Sensodyne, Glaxosmithklein, USA) (n = 9); Control (n = 9) groups. Samples were carried out five pH cycles along 7 days at 37°C for each group. During pH cycling, blocks were put in a demineralization (6 h) and a remineralization solution (18 h). The treatment consisted of 1 min. interaction of enamel surfaces with agent/deionized slurries (1:3 w/w) on a daily basis. The surface microhardness (SMH) was determined before and after pH cycling with a Digital Micro-Vickers Hardness Tester (Wilson Wolpert; Europe BV, 401 MVD, Netherlands). Mineral changes were determined by using FluoreCam® and recovery values were calculated as SMHR% and FΔ%, respectively. Results: All groups showed an enhanced remineralization. There was no significant difference in terms of FΔ% (F = 1.223, P = 0.304) and SMHR% (F = 0.709, P = 0.664) between all groups. Conclusion: The herbals (ginger, honey, and bitter chocolate) examined in this study gave promising results with a high remineralization potential. © 2021 Wolters Kluwer Medknow Publications. All rights reserved.
  • Publication
    Association between serum biomarkers and oral health status in children with chronic kidney disease: A cross-sectional study
    (2023-01-01) KAYA, REMZİYE; ALPAY, HARİKA; KARGÜL, BETÜL; SEZER B., Kodaman Dokumacıgil N., KAYA R., Güven S., Türkkan Ö. N., Çiçek N., ALPAY H., KARGÜL B.
    Objectives: The aim of this study was to investigate the association between serum biomarkers and oral health parameters in children with chronic kidney disease (CKD). Materials and methods: Serum hemoglobin, blood urea nitrogen, serum creatinine, calcium, parathormone, magnesium, and phosphorus levels were measured in 62 children with CKD aged between 4 and 17 years. Intraoral examinations of the patients were performed by two different pediatric dentists. Dental caries was assessed using the decayed-missing-filled-teeth (DMFT/dmft) indexes, and oral hygiene was assessed using the debris (DI), calculus (CI), and simplified oral hygiene (OHI-S) indexes. Spearman’s rho coefficient and generalized linear modeling were used to examine the association between serum biomarkers and oral health parameters. Results: The results of the study showed that there were negative and statistically significant correlations between serum hemoglobin and creatinine levels and dmft scores in pediatric patients with CKD (p = 0.021 and p = 0.019, respectively). Furthermore, blood urea nitrogen levels and DI and OHI-S scores (p = 0.047 and p = 0.050, respectively); serum creatinine levels and DI, CI, and OHI-S scores (p = 0.005, p = 0.047, p = 0.043, respectively); and parathormone levels and CI and OHI-S scores (p = 0.001 and p = 0.017, respectively) were found to be positively and statistically significantly related. Conclusions: There are associations between various serum biomarker levels and dental caries and oral hygiene parameters in pediatric patients with CKD. Clinical relevance: The impact of changes in serum biomarkers on oral and dental health is important for dentists’ and medical professionals\" approaches to patients\" oral and systemic health.
  • Publication
    Evaluation of different remineralization agents in the treatment of natural caries-affected dentin in permanent teeth
    (2023-01-01) KARGÜL, BETÜL; Turkay E. Y., KARGÜL B., Aydinoglu A. K., HAZAR A. B.
    BACKGROUND: In the preventive treatment protocol, providing remineralization of the tissue in demineralized dentin caries is an important step. OBJECTIVE: In this in vitro study, the effectiveness of remineralization agents in natural caries-affected dentin (NCAD) were investigated. METHODS: Forty caries slices were prepared from permanent molar dentin with International Caries Detection and Assessment System (ICDAS 2) (Code 3). The interventions with 8 days pH cycling were as follows: Deionized water (DW); 5% Sodium Fluoride (5% NaF) Varnish; Casein Phosphopeptide-Amorphous Calcium Fluoride Phosphate (CPP-ACFP); Calcium Glyserophosphate (CaGP) + Magnesium (Mg) + Xylitol. DIAGNOdent (Laser Fluorescence, LF), Surface Microhardness (SMH), and X-ray Fluorescence (XRF) Spectroscopy measurements were calculated before and after pH cycling. RESULTS: LF values decreased between 5% NaF, CCP-ACFP and CaGP. NCAD treated with 5% NaF, CaGP and CCP-ACFP exhibited statistically higher hardness compared to the control group. After 5% NaF application, SMH values were significantly higher than the others. There was no statistically significant difference between baseline and after pH cycling hardness of the control group. After cycling, XRF showed that Ca and P concentrations were increased in all groups. CONCLUSION: The application of agents used in the study could be recommended and promoted as a treatment option of caries dentin for conventional management of caries.
  • Publication
    Effect of casein phosphopeptide amorphous calcium fluoride phosphate and calcium glycerophosphate on incisors with molar-incisor hypomineralization: A cross-over, randomized clinical trial
    (2022-01-01) TUĞCU, NİHAN; DURMUŞ, BAŞAK; KARGÜL, BETÜL; BEKİROĞLU, GÜLNAZ NURAL; SEZER B., Tugcu N., Caliskan C., DURMUŞ B., Kupets T., BEKİROĞLU G. N., KARGÜL B., Bourgeois D.
    BACKGROUND:Within the scope of minimally invasive dentistry, the use of different biocompatible remineralization agents on incisors affected by molar-incisor hypomineralization (MIH) gains importance. OBJECTIVE:To evaluate the effect of casein phosphopeptide amorphous calcium fluoride phosphate (CPP-ACFP) and calcium glycerophosphate (CaGP) in mineral density (MD) of white/creamy and yellow/brown demarcated opacities on incisors affected by MIH by means laser fluorescence (LF). METHODS:As a cross-over, randomized trial, twenty-two children with 167 incisors affected by MIH were recruited and randomly assigned to one of the two different agents and crossed over to other agents with two weeks washout in between. Incisors were examined by using LF at all before and after three months periods. RESULTS:The results of the paired t-tests for determining the period effect between the baseline findings showed significant difference in white/creamy and yellow/brown demarcated opacities of LF values for both groups (p < 0.05). The difference between both groups according to after categorization of 20% increasing in MD in the percent of change before and after application on LF values; was not found statistically significant in white/creamy (p = 0.970) and yellow/brown (p = 0.948) opacities. CONCLUSIONS:The primary outcome was CPP-ACFP and CaGP had a positive effect in decreasing hypomineralization on MIH-affected enamel for three months period. Keywords: Molar incisor hypomineralization, minimally invasive dentistry, remineralization, preventive dentistry, casein phosphopeptide amorphous calcium fluoride phosphate, calcium glycerophosphate
  • Publication
    Molar-İncisiv Hipomineralizasyonu olan çocuklarda Türk çocuk ağız sağlığı etki profili kısa formunun (COHIP-SF 19) doğrulaması
    (2023-07-06) TUĞCU, NİHAN; KARGÜL, BETÜL; DURMUŞ, BAŞAK; BEKİROĞLU, GÜLNAZ NURAL; Tuğcu N., Bekiroğlu G. N., Kargül B., Durmuş B.
  • Publication
    Effect of Different Pastes on Remineralization of Initial Enamel Lesion: An in vitro Study
    (2020-11-13) AKBEYAZ ŞİVET, ECEM; KARGÜL, BETÜL; AKBEYAZ ŞİVET E., Parlakyıldız Gokce A. N., KARGÜL B.
  • Publication
    Süt dişlerinde dentin çürüğü tedavisinde farklı remineralizasyon ajanlarının etkisi
    (2021-10-07) KARGÜL, BETÜL; Yilmazkasapoglu E., AYDINOĞLU A., HAZAR A. B., KARGÜL B.