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KEPENEKLİ KADAYİFCİ, EDA

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KEPENEKLİ KADAYİFCİ

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Now showing 1 - 4 of 4
  • Publication
    Kronik granülomatöz hastalıklı olgularda küf ilişkili invaziv enfeksiyonlar: Tek merkez deneyimi
    (2022-03-17) AYDINER, ELİF; KEPENEKLİ KADAYİFCİ, EDA; ÖZEN, AHMET OĞUZHAN; BARIŞ, SAFA; Ergenç Z., Bilgiç Ertan S., Barış S., Aydıner E., Özen A. O., Aslan S., Yılmaz S., Parlak B., Kepenekli Kadayifci E.
  • PublicationOpen Access
    COVID-19 disease characteristics in different pediatric age groups
    (2022-01-01) ŞENYÜREK, BETÜL; BORAN, PERRAN; KEPENEKLİ KADAYİFCİ, EDA; YAKUT, NURHAYAT; KARAHASAN, AYŞEGÜL; AYDINER, ELİF; MEMİŞOĞLU, ASLI; GÖKDEMİR, YASEMİN; ERDEM ERALP, ELA; KARADAĞ, BÜLENT TANER; KEPENEKLİ KADAYİFCİ E., YAKUT N., Ergenc Z., Aydiner O., Sarinoglu R. C., KARAHASAN A., Karakoc-Aydiner E., MEMİŞOĞLU A., GÖKDEMİR Y., ERDEM ERALP E., et al.
    Introduction: Little is known about the COVID-19 disease characteristics and differences between different pediatric age groups. This study aimed to investigate the disease characteristics according to age groups. Methodology: We conducted a retrospective, single-center study of pediatric COVID-19 in a tertiary care hospital in Turkey. The patients were divided into three groups: 15 days-24 months old (Group 1), 25-144 months old (Group 2), and 145-210 months old (Group 3) according to age. Results: A total of 139 pediatric patients with COVID-19 were examined. Twenty-nine patients (20.9%) were in Group 1, 52 (37.4%) were in Group 2, 58 (41.7%) were in Group 3. Thirty-nine patients (28.1%) were hospitalized. The most common symptoms were cough (55.4%) and fever (51.8%). The median chest X-ray (CXR) score of hospitalized patients was 1 (min 0-max 7), and the median CXR score of outpatients was 1 (min 0-max 6). Fever was significantly more frequent in Group 1, and chest pain was more frequent in Group 3. Group 1 had significantly higher WBC, lymphocyte, thrombocyte counts, AST, LDH, D-dimer, and Troponin T levels but lower hemoglobin, total protein, and albumin levels. The treatment included antibiotics, oseltamivir, hydroxychloroquine, and supportive therapy. Only one patient (0.7%) received noninvasive mechanical ventilatory support. Conclusions: As we know the clinical course of COVID-19 in children is less severe than in adults. We also found significant differences in both clinical and laboratory findings between different pediatric age groups which supports the theory that disease pathogenesis is highly variable according to age.
  • Publication
    Invasive mold infections in chronic granulomatous disease: a single-center retrospective cohort
    (2022-05-09) AYDINER, ELİF; BARIŞ, SAFA; ÖZEN, AHMET OĞUZHAN; KEPENEKLİ KADAYİFCİ, EDA; Ergenç Z., Eltan S., Aydıner E., Barış S., Özen A. O. , Aslan S., Yılmaz S., Parlak B., Kepenekli Kadayifci E.
  • PublicationOpen Access
    Single-center experience in vaccination of children in special risk groups: A multidisciplinary institutional consensus protocol
    (2023-09-01) BARIŞ, HATİCE EZGİ; KEPENEKLİ KADAYİFCİ, EDA; ÜTÜK, BURAK; ŞAHİN, PINAR; TOKUÇ, AYŞE GÜLNUR; KOÇ, AHMET; AYDINER, ELİF; BORAN, PERRAN; BARIŞ H. E., Kepenekli E., Sakar F. İ. A., ÜTÜK B., ŞAHİN P., Ergenç Z., TOKUÇ A. G., KOÇ A., Karakoç-Aydıner E., BORAN P.
    Objective: Despite marked improvements in the accessibility of childhood vaccines, knowledge gaps remain about the vaccination of children in special risk groups (SRG). This study aimed to analyze the clinical data of children vaccinated in SRG in a single-center unit to contribute to the clinical evidence for the specific planning of immunization of children in SRG. The secondary aim is to present institutional consensus on the vaccination of children in SRG. Materials and Methods: This retrospective study was conducted at a single-center pediatric vaccination clinic. Patient charts between 2018 and 2021 were retrospectively reviewed, and clinical and laboratory data were extracted. Serial joint meetings with multiple healthcare pro-fessionals were performed to develop an institutional protocol for vaccination. Results: There were 479 children vaccinated between 2018 and 2021 for reasons such as post-chemotherapy, after hematopoietic stem cell transplantation, before/after solid organ trans-plantation, allergies, and chronic diseases. Of these, 298 (62.2%) children vaccinated in the unit due to a history of food or vaccine allergies were excluded. One hundred eighty-one children were vaccinated at a median age of 11 [7-15] years. Most children were vaccinated after treatment for malignancies. Solid tumors were the most frequent malignancy (67%), followed by acute lymphoblastic leukemia (29.0%) and acute myeloid leukemia (4.0%). Institutional vaccination protocols for cancer survivors, hematopoietic stem cells, and solid organ recipient children were developed and presented. Conclusion: There is a need to prepare national guidelines for vaccinating children with altered immunocompetence. Sharing vaccination practices by multidisciplinary vaccination units might increase and provide knowledge to develop national policies.