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KEPEZ, ALPER

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KEPEZ

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ALPER

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Author: TİGEN, ELİF × Subject: Klinik Tıp ×

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    PublicationOpen Access
    Belirgin kardiyovasküler hastalığı olmayan hastalarda COVID-19 mRNA aşısının elektrokar-diyografik parametreler üzerinde herhangi bir etkisi var mı?
    (2022-09-01) KEPEZ, ALPER; TİGEN, ELİF; Küp A., Çelik M., Uslu A., Külahçıoğlu Ş., Tükenmez Tigen E., Demir S., Gülşen K., İzci S., Uygun Kızmaz Y., Kepez A.
    Objective: Electrocardiographic alterations were investigated following the second dosage of COVID-19 mRNA vaccination. Methods: A total of 260 individuals after two doses of COVID-19 vaccine with Pfizer-BioNTech were included in the study. The electrocardiographic parameters recorded at baseline and approximately one week later after two doses of Pfizer-BioNTech vaccine were compared for all patients. Results: PR interval was increased and QTc maximum interval was decreased significantly after second dose COVID-19 mRNA vaccination. Baseline and post-second dose vaccination states regarding P wave dispersion and QT dispersion/Tp-e interval which have been recognized to imply inhomogeneous atrial conduction and heterogeneity in ventricular repolarization were similar between groups. Conclusion: Our findings suggest that there should be no concern related to asymptomatic involvement of the myocardium subsequent the second dose of COVID-19 mRNA vaccination.