Person: DERİCİOĞLU, VOLKAN
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DERİCİOĞLU
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VOLKAN
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Publication Metadata only How do presentation age and CSF opening pressure level affect long-term prognosis of pseudotumor cerebri syndrome in children? Experience of a single tertiary clinic(Springer Science and Business Media Deutschland GmbH, 2021) DAĞÇINAR, ADNAN; Ozturk G., Turkdogan D., Unver O., Dericioglu V., Aslan B., Dagcinar A.Background: Diagnosis and treatment of pseudotumor cerebri syndrome in children is still a challenge for clinicians. The aim of this study is to reveal the influence of presentation age and CSF opening pressure on long-term prognosis of pseudotumor cerebri and share our clinical data of the very young age (≤ 5-year) group. Method: This retrospective study includes the patients followed by the Marmara University Pediatric Neurology Clinic between years 2012 and 2020 diagnosed with definite, probable, or suggestive pseudotumor cerebri syndrome according to modified Friedman criteria. Patients were classified into three groups according to presentation age: group 1: ≤ 5 years old; group 2: 6–10 years; and group 3 > 10 years old. CSF opening pressure was also categorized into three groups as CSF < 20 cmH20; CSF 20–30 cmH20; and CSF > 30 cmH20. Results: One hundred three patients, 62.1% female (n = 64), were enrolled in the study. Group 1 consisted of 16 patients (60% male), group 2 consisted of 30 patients (63.3% female), and group 3 consisted of 57 patients (66.7% female). The mean CSF opening pressure did not differ between the three age groups in our study (p > 0.05). Treatment response was not correlated with CSF opening pressure. Papilledema presence and level of CSF opening pressure were independent of age (p > 0.05). Conclusions: Age at presentation and CSF opening pressure at diagnosis are not any predictive factors that influence long-term prognosis of pseudotumor cerebri syndrome in children. Evaluation and follow-up of children should be done in personalized approach. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Publication Metadata only Pediatrik optik gliom olgularının görme keskinlikleri ile elektofizyolojik ve radyolojik bulgularının değerlendirilmesi(2022-04-23) DERİCİOĞLU, VOLKAN; EKER, NURŞAH; BUĞDAYCI, ONUR; YARGI, BERRU; KURŞUN, MELTEM; SEVİK, MEHMET ORKUN; TOKUÇ, AYŞE GÜLNUR; ŞAHİN, ÖZLEM; Dericioğlu V., Eker N., Buğdayci O., Yargi B., Kurşun M., Sevik M. O. , Tokuç A. G. , Şahin Ö.Amaç:Optik gliom nedeniyle takip edilen pediatrik hastaların en iyi düzeltilmiş görme keskinliği (EİDGK, logMAR), flaş görsel uyarılmış potansiyeller (fVEP) ve manyetik rezonans görüntüleme (MRG) sonuçlarının karşılaştırılması.Yöntem:Marmara Üniversitesi Göz Hastalıkları, Pediatrik Onkoloji ve Radyoloji bölümlerince takip edilen 22 pediatrik optik gliom hastasının 38 gözü çalışmaya dahil edildi. Hastaların başlangıç ve son takipteki EİDGK’leri, MRG’deki optik sinir kalınlıkları (OSK), kontrast tutulumları, sinyal değişimleri ve fVEP’te P2 dalgasının amplitüd ve latansları değerlendirildi.Bulgular:Hastaların yaş ortalamaları 12±5.7 yıl ve kız/erkek oranı 13/9 idi. Ortalama takip süresi 63.95±24.5 ay olarak bulundu. Gözlerin ilk ve son EİDGK’leri sırasıyla, ortanca (1.ve 3. çeyrekler aralığı) 0.2 (0-2.18) ve 0.2 (0-2.3) logMAR (p=0.586); MRG’de ölçülen ortalama OSK’leri sırasıyla, 6.51±6.03 ve 6.31±7.84 mm (p=0.650); fVEP P2 dalga ortalama amplitüdleri sırasıyla, 16.68±14.21 ve 17.93±11.96 mV (p=0.577) ve ortalama latansları sırasıyla, 149.38±50.30 ve 133.39±29.78 ms (p=0.009) olarak saptandı. Son logMAR EİDGK ile OSK (r=0.434, p=0.015), P2 amplitüdü (r=-0.432, p=0.014)) ve P2 latansı (r=0.614, p<0.001) arasında anlamlı orta düzeyde korelasyon olduğu görüldü. fVEP P2 dalga parametreleri ile OSK arasında korelasyon saptanmadı (p>0.05). P2 latansı ile MRG’de görülen sinyal (r=0.426, p=0.013) ve kontrast tutulumu (r=0.386, p=0.027) değişiklikleri arasında anlamlı korelasyon olduğu görüldü.Sonuç:Optik gliom hastalarında fVEP P2 dalga amplitüdleri ve latansları EİDGK ile ilişkili gözükmektedir. Ayrıca, P2 dalga latansının MRG’de görülen sinyal ve kontast tutulumu değişiklikleri ile de ilişkili olduğu görülmektedir. Bu bulgular, özellikle preverbal yaştaki optik gliom hastalarının değerlendirilmesinde ve hastalık ilerlemesinin takibinde fVEP’in kulanılabileceğini göstermektedir.Publication Metadata only Accuracy and reliability of magnetic resonance imaging in the diagnosis of idiopathic intracranial hypertension(2022-10-01) ULUÇ, KAYIHAN; ÇİMŞİT, NURİ ÇAGATAY; ILGIN, CAN; DERİCİOĞLU, VOLKAN; KAHRAMAN KOYTAK, PINAR; Kuzan B. N. , ILGIN C., Kuzan T. Y. , DERİCİOĞLU V., KAHRAMAN KOYTAK P., ULUÇ K., ÇİMŞİT N. Ç.© 2022 Elsevier B.V.Purpose: To determine the diagnostic utility of brain magnetic resonance imaging (MRI) findings in patients with idiopathic intracranial hypertension (IIH) and to investigate the significance of evaluating radiological findings together with neurological and ophthalmological data in the diagnosis of IIH. Materials and Methods: All consecutive patients diagnosed with IIH in our tertiary neuro-ophthalmology center between January 1, 2018 and March 15, 2020, were included in the study. The clinical, radiological, and ophthalmological findings of IIH patients were compared with the control group with similar demographic characteristics. Results: A total of 98 patients, 49 cases and 49 controls, were included in the study. Lateral ventricular index had the highest area under the curve (AUC) value (0.945) for prediction of disease group followed by sella height category (AUC = 0.915) and optic nerve tortuosity (AUC = 0.855) According to the multivariate model we developed, caudate index (OR = 0.572, 95% CI 0.329–0.996), lateral ventricle index (OR = 3.969, 95% CI 1.851–8.509) and bilateral optic nerve tortuosity (OR = 22,784, 95% CI 2.432–213.450) were significant predictors for disease group. Conclusion: Tortuosity in the optic nerve, lateral ventricular index and caudate index can be used as MRI parameters supporting the diagnosis of IIH in clinically suspicious cases. A holistic approach to the clinical and radiological findings of the cases in the diagnosis of IIH can prevent overdiagnosis and enable early correct diagnosis.Publication Metadata only Elaborated analysis of short and long term results of skin blepharoplasty versus skin+muscle blepharoplasty(2022-09-15) DERİCİOĞLU, VOLKAN; ŞAN, BURÇİN; Dericioğlu V., Şan B.Objective:Blepharoplasty surgery is one of the world\"s most commonly performed surgical procedures; however, the effects of including muscle excision in routine skin removal are unclear. It was aimed to evaluate the short and long-term effects of skin only andskin+ muscle excision blepharoplasty on corneal nerves, dry eye parameters, meibomian glands, and eyebrow height.Materials and Methods: Twenty-four eyes (Group-S) of 12 patients who underwent skin excision and 24 eyes (Group-M) of 12 patients who underwent skin+muscle excision were included in the study. Preoperative, 1st week, 1st month, and 1st year Schirmer test, corneal confocal microscopy (CCM) parameters, non-invasive tear break-up time (NTBUT), meibomian gland area (MGA) analysis with infrared meibography, and lateral (LBH) and central (CBH) eyebrow heights were evaluated.Results:There was no significant difference between the two groups regarding age, gender, and preoperatively evaluated parameters (p>0.05). According to the preoperative values, a significant decrease was observed in the CCM parameter of nerve branch density in Group-S at week 1 (19.50±7.88 vs. 16.70±7.72 branches/mm2, p=0.026), and a significant decrease was observed in nerve fiber density in Group-M (19.98 ±7.59 vs. 17.11±7.16 fibers/mm2, p=0.006). A non-significant increase was observed in corneal nerve parameters in the 1st month; however, there was a slight decrease in the 1st year compared to baseline in both groups (p>0.05). Regarding Schimmer and NTBUT, there was no significant change from baseline in all visits in both groups (p>0.05). According to preoperative MGA values, a significant increase was observed in Group-S (18.84±6.02 vs. 21.18± vs.6.10, p=0.005) and Group-M (18.25±8.45 vs. 20.21±8.02, p=0.001) at 1 year. While no significant change was observed in eyebrow height in Group-S, a significant increase was observed in Group-M at 1 year in LBH (16.50±2.81 vs. 17.19±2.40 mm, p=0.007) and 1 month (17.31±2.77 vs. 18.00±2.50 mm, p=0.007) and 1 year (17.31±2.77 vs. 18.13±2.71 mm, p=0.001) in CBH compared to baseline.Conclusion:Elaborated analysis of this cohort showed that both surgical methods had similar effects on corneal nerves and dry eye parameters. Both approaches provided a significant increase in MGA. In addition, including muscle excision in the routine blepharoplasty operation has been found to be a reliable method that will also give a slight elevation in eyebrow position.Publication Metadata only Multicenter case series of standalone XEN implant vs. combination with phacoemulsification in Turkish patients(SPRINGER, 2021) ERASLAN, MUHSİN; Eraslan, Muhsin; Ozcan, Altan Atakan; Dericioglu, Volkan; Ciloglu, EminePurpose To evaluate and compare the efficacy, safety and needling timing and rates of standalone XEN implant vs. combination with phacoemulsification in Turkish patients. Methods Retrospective, multicenter study which included the data of patients, who had open angle glaucoma including primary open angle glaucoma and pseudoexfoliation glaucoma, underwent standalone XEN implantation (XEN alone) and combined surgery with phacoemulsification (XEN + Phaco) between 2016 and 2018. Results The study included 26 eyes of 24 patients in XEN alone group and 32 eyes of 30 patients in XEN + Phaco group. The mean intraocular pressure (IOP) was 23.3 +/- 6.0 mmHg and 24.4 +/- 7.4 mmHg at baseline (p = 0.838), and it reduced to 16.3 +/- 3.0 mmHg and 16.4 +/- 2.3 mmHg at 12-month follow-up (p = 0.436) in XEN alone and XEN + Phaco groups, respectively (reduction: %30 and %33, P = 0.642). The mean number of medications reduced from 2.9 + 0.7 before surgery to 0.9 + 0.9 on month 12. In XEN alone and XEN + Phaco groups, the needling rates were 42.3% and 31.2% (p = 0.491), and the mean time to needling was 3.7 +/- 3.2 months and 4.9 +/- 8.0 months (p = 0.696), respectively. Hypotonia (17.2%) and hyphema (10.3%) were the most frequent complications, respectively. In XEN alone and XEN + Phaco groups, partial success was achieved in 73.1% and 71.9% of eyes when defined as IOP < 18 mmHg with any medication, respectively (p = 0.920). Conclusion The XEN implant provides significant reduction in IOP and number of medications, either standalone or combination with phacoemulsification. Both procedures need intensive postoperative care, requiring needling in approximately one-third of patients.Publication Metadata only Choroidal varix elevates macula following Valsalva manoeuvre(BMJ PUBLISHING GROUP, 2014) ÇERMAN, EREN; Cerman, Eren; Eraslan, Muhsin; Dericioglu, Volkan; Sahin, Ozlem; Cekic, Osman; Mahmutyazicioglu, KamranPublication Metadata only Quantitative measurement of horizontal strabismus with digital photography(MOSBY-ELSEVIER, 2019) ÇERMAN, EREN; Dericioglu, Volkan; Cerman, ErenPURPOSE To develop a method to calculate the gaze angle in photographs and to determine its validity and reliability in real strabismus patients. METHODS Photographs of eyes from 15 orthophoric subjects (n = 1,022) with known gaze angle and imaging distance were investigated with the help of a smartphone application developed by the authors. The application provided measurements of the distance from the geometrical center of the cornea to the light reflex (RD) and corneal diameter (CD). The RD/CD ratio of each gaze angle was recorded. To estimate the eyes' gaze angle, an equation to determine the best-fit line for the gaze angle data according to each RD/CD ratio was created. In a second clinical analysis, this equation was applied to photographs of real strabismus patients (n = 72), and the results were compared with measurements taken by a double-masked strabismus specialist. Separately, an equation was created to calculate the imaging distance using the given interpupillary distance. RESULTS There was a high correlation between the real and estimated gaze angles (r = 0.990, P < 0.001). The mean error of the estimated gaze angle was found to be 0.03(Delta) +/- 4.60(Delta). There was a high correlation between the real and estimated imaging distance (r = 0.997, P < 0.001) and a high correlation between the measurements of the application and the specialist (r = 0.966, P < 0.001). The average error was -0.68(Delta) +/- 6.1(Delta), and the reliability was high (Cronbach's alpha = 0.983). CONCLUSIONS The application measured horizontal strabismus in photographs with high reliability.Publication Metadata only Incidence, Risk Factors and Screening Evaluation of Retinopathy of Prematurity in High Birthweight Infants: A Large Cohort Study in Turkey(TAYLOR & FRANCIS INC) ŞAHİN, ÖZLEM; Dericioglu, Volkan; Butur, Sedat; Celiker, Hande; Sahin, OzlemPurpose: To report and evaluate the incidence and risk factors of retinopathy of prematurity (ROP) and to assess the sensitivity and specificity of Turkish national screening guideline (NSG) in heavier infants with a birth weight (BW) of >1500 g. Methods: The data of 1784 preterm infants with BW>1500 g, who were screened between 2009 and 2016 in a university hospital in Turkey, were analyzed retrospectively. The rates of any stage and severe (treatment-requiring) ROP incidence were investigated. The possible protective and risk factors were evaluated with univariate analyses and logistic regression analysis. Results: The rate of any stage ROP was 14.1% (n = 251). Severe ROP was observed in 11 infants (0.6%), and 2 of the infants (0.1%) had a gestational age (GA)>32 weeks, which fell outside of the NSG. In logistic regression analysis, BW, GA, O-2 therapy duration, and exchange transfusion were determined to be independent risk factors (respectively, p < .001, p < .001, P = .055, and P = .033). Furthermore, antenatal steroid therapy was determined to have a highly significant protective effect on ROP development (p < .001). The sensitivity of Turkish NSG in identifying severe ROP increased from 82% to 100% with the inclusion of risk factors in addition to GA and BW. Conclusion: This study shows the presence of severe ROP in mature and heavy infants in Turkey. The positive effect of antenatal steroid use and the negative impact of exchange transfusion have been demonstrated for ROP development in mature infants. Possible risk factors should be evaluated with GA and BW to avoid missing severe ROP.Publication Metadata only Results of Simultaneous Bilateral Endoscopic Dacryocystorhinostomy, Duration of Surgery, and Evaluation of Success and Complications(2022-09-17) DERİCİOĞLU, VOLKAN; Dericioğlu V.Purpose: It was aimed to evaluate the results of simultaneous bilateral endoscopic dacryocystorhinostomy (DCR).Method: Simultaneous bilateral endoscopic DCR was applied to patients with bilateral acquired nasolacrimal duct obstruction who applied to Marmara University, Department of Ophthalmology between 2020-2022. Patients with punctal - canaliculi occlusion and a history of previous DCR were excluded from the study. Only Kerrison punch and curettes were used for bone excision in all cases, and lacrimal intubation was applied to all eyes. History of dacryocystitis, duration of symptoms and surgery, complications, and functional and anatomical success parameters were evaluated.Results: Twenty-four eyes of 12 patients were included in the study. The female ratio was 4/12 (33.3%), and the mean age of the patients was 50.9±9.1 years. Six eyes (25%) had a history of dacryocystitis. The mean time to development of symptoms was 9.21±4.14 months. The mean operation time per eye was 37.08±6.41 (min:25-max:50) minutes. The functional and anatomical success rates at 3 months were 91.7% (n=22) and 95.8% (n=23), respectively; and 6 months success rates were 87.5% (n=21) and 91.7% (n=22), respectively. While no perioperative complication was observed, the hematoma was seen in 4 eyes (16.6%), and intranasal bleeding occurred in 2 eyes (8.3%) postoperatively. In one of the anatomically unsuccessful eyes, the lacrimal intubation tube extruded on the 3rd postoperative day, and another eye had a history of dacryocystitis.Conclusion: Simultaneous endoscopic DCR can be applied as a useful method in bilateral acquired nasolacrimal duct obstructions with its high anatomical and functional success rate, short operation time, and low complication rates.Publication Metadata only Akut görme kaybı ile başvuran pediatrik hastalardaki bulgularımız(2022-04-23) TIRAŞ, NİMET ZEYNEP; DERİCİOĞLU, VOLKAN; AKBEYAZ, İSMAİL HAKKI; ÜNVER, OLCAY; Tiraş N. Z. , Dericioğlu V., Akbeyaz I. H. , Ünver O.GİRİŞVE AMAÇ:Görme kaybı ile başvuran pediatrik hastaların demografik verileri, verilen tedavileri ve tanılarını incelemek.YÖNTEM:Marmara Üniversitesi Hastanesi acil servisine 2021 yılı içerisinde optik sinir veya nörolojik kaynaklı görme keskinliği veya görme alanı kaybı ile başvuran hastalar çalışmaya dahil edildi. Diğer oftalmolojik nedenli görme kayıpları çalışmadan dışlandı. Hastaların demografik verileri, manyetik rezonans görüntülemeleri (MRG), en iyi düzeltilmişgörme keskinlikleri (EİDGK) (logMAR), oftalmolojik ve nörolojik muayenelerine ek olarak verilen tedaviler ve sonuç tanıları incelendi.BULGULAR:Çalışmaya 25 hasta dahil edildi. Hastaların ortalama yaşı 13.8±3.2 yıldı ve 15 (%60) hasta kız çocuğuydu. Hastalardan 11’i (%44) unilateral, 14’ü (%56) bilateral görme kaybı ile başvurdu. Hastaların %28’inde (n=7) ağrılı görme kaybı bulunurken, %44’ünde (n=11) eşlik eden ek nörolojik semptomlar vardı.İlk başvuru anında 15 hastada (%60) optik disk kabarıklığı mevcuttu. Beyin MRG değerlendirilmesinde 9 hastada (%36) optik sinirin orbital kısmında kontrast tutulumu izlenirken, ek kraniyal patolojik bulgu 11 hastada (%44) görüldü. Onbeşhastaya (%60) uygulanan lomber ponksiyonda ortalama açılışbasıncı 28.27 ± 23 cmH2O olarak bulundu. Hastaların 14’üne (%56) intravenöz metilprednizolon, 5’ine (%20) asetazolomid ve boşaltıcı LP uygulanırken, 6 hasta (%24) destek tedavisi ile takip edildi. Toplam 41 gözün başvuru anındaki ortalama EİDGK 1.02±1.09 logMAR ve sonuç EİDGK 0.48±0.79 logMAR olarak bulundu (p=0.001). Takiplerde hastaların 8’ine (%32) idiyopatik optik nörit, 5’ine (%20) idiyopatik intrakraniyal hipertansiyon (IIH), 4’üne (%16) multiple skleroz (MS), 3’er hasta (%12) metabolik ve herediter optik nöropati, 1 hastaya (%4) MOG ilişkili optik nörit ve 1 hastaya (%4) iskemik optik nöropati nedeniyle görme kaybı tanısı konuldu.TARTIŞMA VE SONUÇ:Acil servise başvuran pediyatrik görme kayıplarının en sık nedenini idiyopatik optik nörit oluşturmakta ve bunu IIH ve MS takip etmektedir.