Person: DERİCİOĞLU, VOLKAN
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DERİCİOĞLU
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VOLKAN
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Publication Open Access Predictive factors of complications and visual outcomes after pediatric cataract surgery: A single referral center study from Türkiye(2023-10-01) DERİCİOĞLU, VOLKAN; SEVİK, MEHMET ORKUN; BAĞATUR VURGUN, ELİF; ÇERMAN, EREN; DERİCİOĞLU V., SEVİK M. O., BAĞATUR VURGUN E., ÇERMAN E.Objectives: To evaluate the predictive factors of complications and visual acuity outcomes in pediatric cataract patients. Materials and Methods: This retrospective, observational clinical study included 80 eyes of 50 patients treated for pediatric cataracts between 2010 and 2020. The eyes were divided into Group I (congenital cataracts, n=38) and Group II (developmental cataracts, n=42). Group II was also divided into Group IIA (aphakic, n=21) and Group IIB (pseudophakic, n=21). The effects of the age, laterality, cataract morphology, intraocular lens implantation, preoperative nystagmus/strabismus, and intraoperative anterior hyaloid rupture on complications and final best-corrected visual acuity (BCVA; logMAR) were evaluated. Results: The median (interquartile range) age and follow-up time were 28 (5-79) months and 60 (29-84) months, respectively. There was a significant difference in mean final BCVA between Group I (0.79±0.46) and Group II (0.57±0.51) (p=0.047); however, no difference was observed between Group IIA and Group IIB (p=0.541). Having congenital cataract (p=0.045), preoperative nystagmus/strabismus (p=0.042), total/ mature cataract (p<0.001), and postoperative complications (p=0.07) were significantly associated with final BCVA. However, in multivariate analysis, only total/mature cataract (β: 0.52, p<0.001) and having any complication (β: 0.24, p=0.018) were associated with final BCVA. Congenital cataract and intraoperative anterior hyaloid rupture were the only significant risk factors of postoperative complications on univariate (p=0.027 and p=0.003, respectively) and binary logistic regression analysis (odds ratio [OR]: 2.95 [95% confidence interval: 1.07-8.15], p=0.036 and OR: 4.28 [95% confidence interval: 1.55-11.77], p=0.005, respectively). Conclusion: Total/mature cataract and the presence of any postoperative complication adversely affected the final BCVA. Having a congenital cataract and intraoperative anterior hyaloid membrane rupture increased the risk of complications.Publication Open Access Juvenile Xanthogranuloma Presented with Buphthalmos and Corneal Clouding in Neonatal Period: A Case Report(2022-05-01) DERİCİOĞLU, VOLKAN; SEVİK, MEHMET ORKUN; ERASLAN, MUHSİN; DERİCİOĞLU V., SEVİK M. O. , ERASLAN M., Dirican B., Yücelten D., Cinel L.Aim: To report an ocular juvenile xanthogranuloma (JXG) case presented with buphthalmos, corneal cloudiness, and normal intraocular pressure (IOP) in the neonatal period and treated with Ahmed glaucoma valve (AGV) implantation. Background: JXG is a rare disorder predominantly seen in infants, but the neonatal presentation is extraordinary. Although spontaneous hyphema is a common presenting sign in JXG, buphthalmos and corneal opacity in the neonatal period were reported only in one case, which had high IOP values at presentation. Case presentation: Sixteen-day-old male patient presented with buphthalmos, diffuse corneal clouding, and 11 mm Hg of IOP value in the right eye. IOP increased to 28 mm Hg three weeks later, and spontaneous hyphema developed, which did not respond to antiglaucomatous medications and topical corticosteroids. AGV was implanted, and the IOP decreased to 13 mm Hg postoperatively. In the follow-ups, numerous firm yellowish nodules were noticed on the patient’s skin during the examination under general anesthesia. Histopathological examination of the skin nodules was compatible with the diagnosis of JXG. Lens subluxation and phacodonesis were developed during the follow-up and were managed with pars plana lensectomy. After a silent period of 3 months, epithelial ingrowth was determined around the side port entrance. Unfortunately, the ingrowth did not respond to cryotherapy and resulted in phthisis bulbi. Pathological evaluation of the enucleated phthisic eye revealed posterior segment involvement. Conclusion: Ocular JXG can be present with buphthalmos, corneal opacity, and normal IOP values without any skin lesions in the neonatal period. Neonatal presentation of JXG may be associated with limited medical therapy response and aggressive disease course. Clinical significance: This case report introduces the second ocular JXG case, which presented with buphthalmos and corneal cloudiness, and the third pathologically proven posterior segment involvement of JXG in the literature.Publication Metadata only Pediatrik optik gliom olgularının görme keskinlikleri ile elektofizyolojik ve radyolojik bulgularının değerlendirilmesi(2022-04-23) DERİCİOĞLU, VOLKAN; EKER, NURŞAH; BUĞDAYCI, ONUR; YARGI, BERRU; KURŞUN, MELTEM; SEVİK, MEHMET ORKUN; TOKUÇ, AYŞE GÜLNUR; ŞAHİN, ÖZLEM; Dericioğlu V., Eker N., Buğdayci O., Yargi B., Kurşun M., Sevik M. O. , Tokuç A. G. , Şahin Ö.Amaç:Optik gliom nedeniyle takip edilen pediatrik hastaların en iyi düzeltilmiş görme keskinliği (EİDGK, logMAR), flaş görsel uyarılmış potansiyeller (fVEP) ve manyetik rezonans görüntüleme (MRG) sonuçlarının karşılaştırılması.Yöntem:Marmara Üniversitesi Göz Hastalıkları, Pediatrik Onkoloji ve Radyoloji bölümlerince takip edilen 22 pediatrik optik gliom hastasının 38 gözü çalışmaya dahil edildi. Hastaların başlangıç ve son takipteki EİDGK’leri, MRG’deki optik sinir kalınlıkları (OSK), kontrast tutulumları, sinyal değişimleri ve fVEP’te P2 dalgasının amplitüd ve latansları değerlendirildi.Bulgular:Hastaların yaş ortalamaları 12±5.7 yıl ve kız/erkek oranı 13/9 idi. Ortalama takip süresi 63.95±24.5 ay olarak bulundu. Gözlerin ilk ve son EİDGK’leri sırasıyla, ortanca (1.ve 3. çeyrekler aralığı) 0.2 (0-2.18) ve 0.2 (0-2.3) logMAR (p=0.586); MRG’de ölçülen ortalama OSK’leri sırasıyla, 6.51±6.03 ve 6.31±7.84 mm (p=0.650); fVEP P2 dalga ortalama amplitüdleri sırasıyla, 16.68±14.21 ve 17.93±11.96 mV (p=0.577) ve ortalama latansları sırasıyla, 149.38±50.30 ve 133.39±29.78 ms (p=0.009) olarak saptandı. Son logMAR EİDGK ile OSK (r=0.434, p=0.015), P2 amplitüdü (r=-0.432, p=0.014)) ve P2 latansı (r=0.614, p<0.001) arasında anlamlı orta düzeyde korelasyon olduğu görüldü. fVEP P2 dalga parametreleri ile OSK arasında korelasyon saptanmadı (p>0.05). P2 latansı ile MRG’de görülen sinyal (r=0.426, p=0.013) ve kontrast tutulumu (r=0.386, p=0.027) değişiklikleri arasında anlamlı korelasyon olduğu görüldü.Sonuç:Optik gliom hastalarında fVEP P2 dalga amplitüdleri ve latansları EİDGK ile ilişkili gözükmektedir. Ayrıca, P2 dalga latansının MRG’de görülen sinyal ve kontast tutulumu değişiklikleri ile de ilişkili olduğu görülmektedir. Bu bulgular, özellikle preverbal yaştaki optik gliom hastalarının değerlendirilmesinde ve hastalık ilerlemesinin takibinde fVEP’in kulanılabileceğini göstermektedir.Publication Metadata only Accuracy and reliability of magnetic resonance imaging in the diagnosis of idiopathic intracranial hypertension(2022-10-01) ULUÇ, KAYIHAN; ÇİMŞİT, NURİ ÇAGATAY; ILGIN, CAN; DERİCİOĞLU, VOLKAN; KAHRAMAN KOYTAK, PINAR; Kuzan B. N. , ILGIN C., Kuzan T. Y. , DERİCİOĞLU V., KAHRAMAN KOYTAK P., ULUÇ K., ÇİMŞİT N. Ç.© 2022 Elsevier B.V.Purpose: To determine the diagnostic utility of brain magnetic resonance imaging (MRI) findings in patients with idiopathic intracranial hypertension (IIH) and to investigate the significance of evaluating radiological findings together with neurological and ophthalmological data in the diagnosis of IIH. Materials and Methods: All consecutive patients diagnosed with IIH in our tertiary neuro-ophthalmology center between January 1, 2018 and March 15, 2020, were included in the study. The clinical, radiological, and ophthalmological findings of IIH patients were compared with the control group with similar demographic characteristics. Results: A total of 98 patients, 49 cases and 49 controls, were included in the study. Lateral ventricular index had the highest area under the curve (AUC) value (0.945) for prediction of disease group followed by sella height category (AUC = 0.915) and optic nerve tortuosity (AUC = 0.855) According to the multivariate model we developed, caudate index (OR = 0.572, 95% CI 0.329–0.996), lateral ventricle index (OR = 3.969, 95% CI 1.851–8.509) and bilateral optic nerve tortuosity (OR = 22,784, 95% CI 2.432–213.450) were significant predictors for disease group. Conclusion: Tortuosity in the optic nerve, lateral ventricular index and caudate index can be used as MRI parameters supporting the diagnosis of IIH in clinically suspicious cases. A holistic approach to the clinical and radiological findings of the cases in the diagnosis of IIH can prevent overdiagnosis and enable early correct diagnosis.Publication Metadata only Elaborated analysis of short and long term results of skin blepharoplasty versus skin+muscle blepharoplasty(2022-09-15) DERİCİOĞLU, VOLKAN; ŞAN, BURÇİN; Dericioğlu V., Şan B.Objective:Blepharoplasty surgery is one of the world\"s most commonly performed surgical procedures; however, the effects of including muscle excision in routine skin removal are unclear. It was aimed to evaluate the short and long-term effects of skin only andskin+ muscle excision blepharoplasty on corneal nerves, dry eye parameters, meibomian glands, and eyebrow height.Materials and Methods: Twenty-four eyes (Group-S) of 12 patients who underwent skin excision and 24 eyes (Group-M) of 12 patients who underwent skin+muscle excision were included in the study. Preoperative, 1st week, 1st month, and 1st year Schirmer test, corneal confocal microscopy (CCM) parameters, non-invasive tear break-up time (NTBUT), meibomian gland area (MGA) analysis with infrared meibography, and lateral (LBH) and central (CBH) eyebrow heights were evaluated.Results:There was no significant difference between the two groups regarding age, gender, and preoperatively evaluated parameters (p>0.05). According to the preoperative values, a significant decrease was observed in the CCM parameter of nerve branch density in Group-S at week 1 (19.50±7.88 vs. 16.70±7.72 branches/mm2, p=0.026), and a significant decrease was observed in nerve fiber density in Group-M (19.98 ±7.59 vs. 17.11±7.16 fibers/mm2, p=0.006). A non-significant increase was observed in corneal nerve parameters in the 1st month; however, there was a slight decrease in the 1st year compared to baseline in both groups (p>0.05). Regarding Schimmer and NTBUT, there was no significant change from baseline in all visits in both groups (p>0.05). According to preoperative MGA values, a significant increase was observed in Group-S (18.84±6.02 vs. 21.18± vs.6.10, p=0.005) and Group-M (18.25±8.45 vs. 20.21±8.02, p=0.001) at 1 year. While no significant change was observed in eyebrow height in Group-S, a significant increase was observed in Group-M at 1 year in LBH (16.50±2.81 vs. 17.19±2.40 mm, p=0.007) and 1 month (17.31±2.77 vs. 18.00±2.50 mm, p=0.007) and 1 year (17.31±2.77 vs. 18.13±2.71 mm, p=0.001) in CBH compared to baseline.Conclusion:Elaborated analysis of this cohort showed that both surgical methods had similar effects on corneal nerves and dry eye parameters. Both approaches provided a significant increase in MGA. In addition, including muscle excision in the routine blepharoplasty operation has been found to be a reliable method that will also give a slight elevation in eyebrow position.Publication Open Access A useful method for the practice of pneumatic retinopexy: Slit-lamp laser photocoagulation through the gas bubble(2023-05-01) SEVİK, MEHMET ORKUN; KUBAT, BETÜL; DERİCİOĞLU, VOLKAN; ŞAHİN, ÖZLEM; Aykut A., SEVİK M. O., KUBAT B., DERİCİOĞLU V., ŞAHİN Ö.This study aimed to demonstrate the laser retinopexy method through the gas bubble under a slit-lamp biomicroscope using a wide-field contact lens to treat rhegmatogenous retinal detachment (RRD) with pneumatic retinopexy (PR) and report its anatomical and functional results. This single-center, retrospective case series included RRD patients treated with PR using sulfur hexafluoride (SF6). The demographics, preoperative factors, and anatomical and functional outcomes were collected from the patient files. The single-procedure success rate of PR at postoperative 6th months was 70.8% (17/24 eyes), and the final success rate after secondary surgeries was 100%. The BCVA was better in the successful PR eyes at postoperative 3rd (p = 0.011) and 6th month (p = 0.016) than in failed eyes. No single preoperative factor was associated with PR success. The single-procedure success rate of PR using the laser retinopexy method through the gas bubble with a wide-field contact lens system seems comparable to the PR literature.Publication Open Access Choroidal vascularity index as an activity criterion and a treatment response measure in chronic central serous chorioretinopathy(2023-01-01) ŞAHİN, ÖZLEM; SEVİK, MEHMET ORKUN; ÇAM, FURKAN; DERİCİOĞLU, VOLKAN; SEVİK M. O., Aykut A., ÇAM F., DERİCİOĞLU V., ŞAHİN Ö.Purpose: This study aimed to evaluate the choroidal vascularity index (CVI) as an activity criterion in chronic central serous chorioretinopathy (CSC) and as a measure of treatment response after full-dose-full-fluence photodynamic therapy (fd-ff-PDT). Methods: This fellow-eye-controlled, retrospective cohort study included 23 patients with unilateral chronic CSC treated with fd-ff-PDT (6 mg/m2; 50 μcm2; 83 s). Subfoveal choroidal thickness (SFCT, μm) and CVI (%) of the affected and fellow eyes at baseline as well as at 1, 3 and 6 months after fd-ff-PDT were compared. Results: The patients\" mean age was 43.4 ± 7.3 years, and 18 (78.3%) were male. CVI was comparable between the affected and fellow eyes at baseline (66.09 ± 1.56 vs. 65.84 ± 1.57, p = 0.59). However, it became significantly lower in the affected eyes 1 (64.45 ± 1.68 vs. 65.87 ± 1.19, p = 0.002), 3 (64.21 ± 2.08 vs. 65.71 ± 1.59, p = 0.009) and 6 (64.47 ± 2.19 vs. 65.62 ± 1.52, p = 0.045) months after fd-ff-PDT. The mean SFCT and the mean CVI were significantly decreased in the affected eyes at all follow-up visits compared with baseline after fd-ff-PDT (p < 0.001). Conclusion: At baseline, CVI was comparable between affected and fellow eyes. Therefore, its use as an activity criterion in chronic CSC patients is questionable. However, it was significantly decreased in fd-ff-PDT-treated eyes, supporting its role as a measure of treatment response in chronic CSC.Publication Open Access Effect of age on primary balloon dacryocystoplasty and probing success in congenital nasolacrimal duct obstruction(2022-11-01) ÇERMAN, EREN; SEVİK, MEHMET ORKUN; ERASLAN, MUHSİN; DERİCİOĞLU, VOLKAN; DERİCİOĞLU V., Sevik M. O., Sacu S. S., ERASLAN M., ÇERMAN E.Purpose To compare the success rates of balloon dacryocystoplasty (BDP) and probing as a primary procedure in congenital nasolacrimal duct obstruction (CNLDO) and investigate the effect of age on both procedures. Methods A total of 135 patients (171 eyes) with simple and incomplete complex CNLDO were included in this retrospective study; complete complex CNLDO cases were excluded. The success rates for primary BDP (118 eyes) and for probing (53 eyes) were compared overall and among the age groups; Group 1 (12-24 months old), Group 2 (25-36 months old), and Group 3 (> 36 months old). Results Mean age of the patients was 41.5 +/- 27.2 months for primary BDP, and 21.8 +/- 10.8 months for probing (p < 0.001). Overall success rates for primary BDP and probing were 81.1% (43/53) and 76.3% (90/118), respectively (p = 0.481). Success rates for BDP and probing among age groups were 93.8% and 85.3% in Group 1 (p = 0.360), 93.3% and 50.0% in Group 2 (p = 0.012), and 63.6% and 27.3% in Group 3 (p = 0.052), respectively. Cox regression analysis showed that the median ages were 18 months for probing and 36 months for primary BDP. The Poisson regression model showed that for every 1-month increase in patients\" age, the success rate of probing decreased by 9.7%. Conclusion Probing success decreased to a point where different treatment options such as primary BDP can be discussed with the patients\" parents after 18 months of age. The success of BDP decreased after 36 months, while it maintained a high success rate between 24 and 36 months as primary treatment.Publication Metadata only Results of Simultaneous Bilateral Endoscopic Dacryocystorhinostomy, Duration of Surgery, and Evaluation of Success and Complications(2022-09-17) DERİCİOĞLU, VOLKAN; Dericioğlu V.Purpose: It was aimed to evaluate the results of simultaneous bilateral endoscopic dacryocystorhinostomy (DCR).Method: Simultaneous bilateral endoscopic DCR was applied to patients with bilateral acquired nasolacrimal duct obstruction who applied to Marmara University, Department of Ophthalmology between 2020-2022. Patients with punctal - canaliculi occlusion and a history of previous DCR were excluded from the study. Only Kerrison punch and curettes were used for bone excision in all cases, and lacrimal intubation was applied to all eyes. History of dacryocystitis, duration of symptoms and surgery, complications, and functional and anatomical success parameters were evaluated.Results: Twenty-four eyes of 12 patients were included in the study. The female ratio was 4/12 (33.3%), and the mean age of the patients was 50.9±9.1 years. Six eyes (25%) had a history of dacryocystitis. The mean time to development of symptoms was 9.21±4.14 months. The mean operation time per eye was 37.08±6.41 (min:25-max:50) minutes. The functional and anatomical success rates at 3 months were 91.7% (n=22) and 95.8% (n=23), respectively; and 6 months success rates were 87.5% (n=21) and 91.7% (n=22), respectively. While no perioperative complication was observed, the hematoma was seen in 4 eyes (16.6%), and intranasal bleeding occurred in 2 eyes (8.3%) postoperatively. In one of the anatomically unsuccessful eyes, the lacrimal intubation tube extruded on the 3rd postoperative day, and another eye had a history of dacryocystitis.Conclusion: Simultaneous endoscopic DCR can be applied as a useful method in bilateral acquired nasolacrimal duct obstructions with its high anatomical and functional success rate, short operation time, and low complication rates.Publication Open Access Untitled reply(2022-07-01) SEVİK, MEHMET ORKUN; ÇAM, FURKAN; ŞAHİN, ÖZLEM; DERİCİOĞLU, VOLKAN; SEVİK M. O., ÇAM F., Aykut A., DERİCİOĞLU V., ŞAHİN Ö.