Publication: Çocuklarda renal östeodistrofi
Abstract
Çocuklarda renal osteodistrofi (ROD), kalsiyum, fosfor metabolizmasında değişiklikler ile paratiroid hormonu ve D vitamini arasındaki karmaşık ilişki sonucu gelişen bir komplikasyondur. Erişkinlerden farklı olarak, böbrek yetersizliği olan çocuklarda görülen ROD, büyüme geriliği ve kalıcı kemik deformiteleri ile birlikte ileride fiziksel özürlere neden olabilir. Bu derlemede, böbrek yetersizliği olan çocuklarda ROD’de yaklaşım ve tedavi sunulmuştur.
Childhood renal osteodystrophy (ROD) is the consequence of disturbances in calcium and phosphorus metabolism and their complex interrelationship with parathyroid hormone and vitamin D. Unlike adults, ROD in children may lead to growth failure and permanent bone deformities which may cause disabling complications. In this review, an approach to the management and treatment of ROD in children with chronic renal failure is presented.
Childhood renal osteodystrophy (ROD) is the consequence of disturbances in calcium and phosphorus metabolism and their complex interrelationship with parathyroid hormone and vitamin D. Unlike adults, ROD in children may lead to growth failure and permanent bone deformities which may cause disabling complications. In this review, an approach to the management and treatment of ROD in children with chronic renal failure is presented.